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AMG 837 hemicalcium salt - ≥98%(HPLC), high purity , CAS No.1291087-14-3

COA

Grade & Purity:

≥98%(HPLC)

Cas Number: 1291087-14-3
Molecular Weight: 457.47
PubChem CID: 124201854

In stock

Item Number

A286688

Grouped product items
SKU	Size	Availability	Price	Qty
A286688-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$171.90
A286688-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$722.90

Potent FFA1 (GPR40) partial agonist

View related series

Class A GPCR (4138) Free Fatty Acid Receptor (52) GPCR/G Protein (3172)

Basic Description

Synonyms	(βS)-β-1-Propyn-1-yl-4-[[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methoxy]benzenepropanoic acid hemicalcium salt
Specifications & Purity	≥98%(HPLC)
Biochemical and Physiological Mechanisms	Potent free fatty acid receptor 1 (FFA1/GPR40) partial agonist (EC50values are 13.5, 22.6 and 31.7 nM at human, mouse and rat receptors, respectively). Interacts allosterically with full FFA1 agonistDocosahexaenoic acid. Potentiates glucose-dependent stim
Storage Temp	Store at 2-8°C
Shipped In	Wet ice This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

IUPAC Name	calcium;(3S)-3-[4-[[3-[4-(trifluoromethyl)phenyl]phenyl]methoxy]phenyl]hex-4-ynoate
INCHI	InChI=1S/2C26H21F3O3.Ca/c21-2-4-21(16-25(30)31)20-9-13-24(14-10-20)32-17-18-5-3-6-22(15-18)19-7-11-23(12-8-19)26(27,28)29;/h23,5-15,21H,16-17H2,1H3,(H,30,31);/q;;+2/p-2/t2*21-;/m00./s1
InChIKey	WCZAHGONZBHQSA-HRQBZJEISA-L
Smiles	CC#CC(CC(=O)[O-])C1=CC=C(C=C1)OCC2=CC(=CC=C2)C3=CC=C(C=C3)C(F)(F)F.CC#CC(CC(=O)[O-])C1=CC=C(C=C1)OCC2=CC(=CC=C2)C3=CC=C(C=C3)C(F)(F)F.[Ca+2]
PubChem CID	124201854
Molecular Weight	457.47

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Solubility	Solvent:DMSO, Max Conc. mg/mL: 45.75, Max Conc. mM: 100

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