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Aleplasinin - 99%, high purity , Plasminogen activator inhibitor-1 inhibitor, CAS No.481629-87-2, Plasminogen activator inhibitor-1 inhibitor

Name: Aleplasinin - 99%, high purity , Plasminogen activator inhibitor-1 inhibitor, CAS No.481629-87-2, Plasminogen activator inhibitor-1 inhibitor
Price: 39.9 USD
Availability: InStock

COA

Grade & Purity:

Moligand™

≥98%

Cas Number: 481629-87-2
Molecular Weight: 425.52
PubChem CID: 10224267

In stock

Item Number

A651846

Grouped product items
SKU	Size	Availability	Price
A651846-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$39.90
A651846-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$105.90
A651846-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$369.90
A651846-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$999.90

View related series

Amino Acid/Protein Metabolism (1836) Amyloid-β (136) Metabolic Enzyme/Protease (4860) Neuronal Signaling (3320) PAI-1 (26)

Synonyms	Aleplasinin \| Q2640993 \| Aleplasinin (USAN/INN) \| CHEMBL325424 \| DB12635 \| Aleplasinin [USAN:INN] \| 1H-INDOL-3-ACETIC ACID, 1-((4-(1,1-DIMETHYLETHYL)PHENYL)METHYL)-5-(3-METHYLPHENYL)-.ALPHA.-OXO- \| HSXLMAFNWCSZGP-UHFFFAOYSA-N \| D08656 \| PAZ-417 \| 2-(1-(4-
Specifications & Purity	Moligand™, ≥98%
Biochemical and Physiological Mechanisms	Aleplasinin is a potent, BBB-penetrated and selectiveSERPINE1 (PAI-1, Plasminogen activator inhibitor-1) inhibitor. Aleplasinin increases amyloid-β (Aβ) catabolism and ameliorates amyloid-related pathology. Aleplasinin improves memory deficiency. Aleplasi
Storage Temp	Protected from light,Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Plasminogen activator inhibitor-1 inhibitor

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Indoles and derivatives
Subclass	Indolyl carboxylic acids and derivatives
Intermediate Tree Nodes	Not available
Direct Parent	Indole-3-acetic acid derivatives
Alternative Parents	N-alkylindoles Phenylpropanes Indoles Aryl ketones Toluenes Substituted pyrroles Alpha-keto acids and derivatives Vinylogous amides Alpha-hydroxy ketones Heteroaromatic compounds Monocarboxylic acids and derivatives Azacyclic compounds Carboxylic acids Organic oxides Organonitrogen compounds Hydrocarbon derivatives
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Indole-3-acetic acid derivative - N-alkylindole - Indole - Phenylpropane - Aryl ketone - Toluene - Monocyclic benzene moiety - Alpha-keto acid - Benzenoid - Substituted pyrrole - Keto acid - Heteroaromatic compound - Vinylogous amide - Pyrrole - Alpha-hydroxy ketone - Ketone - Carboxylic acid derivative - Carboxylic acid - Azacycle - Monocarboxylic acid or derivatives - Organic nitrogen compound - Organic oxygen compound - Organic oxide - Carbonyl group - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as indole-3-acetic acid derivatives. These are compounds containing an acetic acid (or a derivative) linked to the C3 carbon atom of an indole.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

IUPAC Name	2-[1-[(4-tert-butylphenyl)methyl]-5-(3-methylphenyl)indol-3-yl]-2-oxoacetic acid
INCHI	InChI=1S/C28H27NO3/c1-18-6-5-7-20(14-18)21-10-13-25-23(15-21)24(26(30)27(31)32)17-29(25)16-19-8-11-22(12-9-19)28(2,3)4/h5-15,17H,16H2,1-4H3,(H,31,32)
InChIKey	HSXLMAFNWCSZGP-UHFFFAOYSA-N
Smiles	CC1=CC(=CC=C1)C2=CC3=C(C=C2)N(C=C3C(=O)C(=O)O)CC4=CC=C(C=C4)C(C)(C)C
Isomeric SMILES	CC1=CC(=CC=C1)C2=CC3=C(C=C2)N(C=C3C(=O)C(=O)O)CC4=CC=C(C=C4)C(C)(C)C
PubChem CID	10224267
Molecular Weight	425.52

Solubility	DMSO : 250 mg/mL (587.52 mM; Need ultrasonic)
Sensitivity	Light sensitive
Molecular Weight	425.500 g/mol
XLogP3	6.700
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	6
Exact Mass	425.199 Da
Monoisotopic Mass	425.199 Da
Topological Polar Surface Area	59.300 Å²
Heavy Atom Count	32
Formal Charge	0
Complexity	675.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Aleplasinin - 99%, high purity , Plasminogen activator inhibitor-1 inhibitor, CAS No.481629-87-2, Plasminogen activator inhibitor-1 inhibitor

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