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ALDH1A3-IN-1 - 98%, high purity , CAS No.1695970-90-1

    Grade & Purity:
  • ≥98%
In stock
Item Number
A648564
Grouped product items
SKU Size
Availability
Price Qty
A648564-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$85.90
A648564-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$145.90
A648564-25mg
25mg
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Production requires sourcing of materials. We appreciate your patience and understanding.
$300.90
A648564-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$485.90
A648564-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$780.90

Basic Description

Specifications & Purity ≥98%
Biochemical and Physiological Mechanisms ALDH1A3-IN-1 (Compound 14) is a potent ALDH1A3 inhibitor, with an IC 50 of 0.63 µM and a K i of 0.46 µM. ALDH1A3-IN-1 can be studied in prostate cancer.
Storage Temp Protected from light,Store at -80°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

ALDH1A3-IN-1 (Compound 14) is a potent ALDH1A3 inhibitor, with an IC 50 of 0.63 µM and a K i of 0.46 µM. ALDH1A3-IN-1 can be studied in prostate cancer

In Vitro

ALDH1A3-IN-1 (Compound 14) (0-200 µM, 96 h) shows antiproliferative activity in prostate cancer cell lines. ALDH1A3-IN-1 (0-200 µM, 72 h) reduces cell viability of primary prostate cells in a dose-dependent manner. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Proliferation AssayCell Line: PC3, LNCaP, and DU145 cells Concentration: 12.5-200 µM Incubation Time: 96 h Result: Showed antiproliferative activity with IC 50 values of 47 ± 6, 25 ± 1, and 61 ± 5 µM against PC3, LNCaP, and DU145 cells. Cell Viability AssayCell Line: Primary cells cultured at early passage from human prostate tissue biopsies Concentration: 50 and 200 μM Incubation Time: 72 h Result: Resulted a dose-dependent reduction in percentage cell viability of primary prostate epithelial cultures.

Form:Liquid

IC50& Target:ALDH1A3 0.63 μM (IC 50 ) ALDH1A1 7.08 μM (IC 50 ) ALDH3A1 8.00 μM (IC 50 ) ALDH1A3 0.46 μM (Ki) ALDH1A3 26.92 μM (Km)

Names and Identifiers

Smiles O=CC1=CC(Br)=C(C=C1)N(CCC)CCC
Molecular Weight 284.19

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

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