20 Citations
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Basic Description
| Product Name | Albumin solution human, CAS No.70024-90-7 |
|---|---|
| Product Description |
Human serum albumin (HSA) is a monomeric, globular, and α-helical protein that constitutes a major part of human blood plasma proteins. This single-chain polypeptide protein contains 585 amino acid residues and 17 internal disulfide bridges and one free cysteine. Human serum albumin undergoes three different post-translational modifications: oxidation, glycation, and S-nitrosylation. Modifications usually occur on the surface of the globular protein, and do not significantly affect conformation. However, modification strongly affects binding of fatty acids and drug molecules. Application: Albumin solution human has been used as a supplement in RPMI 1640 media during polymorphonuclear cell (PMN) incubation. It has also been used as a culture media for the differentiation and maturation of monocyte-derived dendritic cells. |
| Specifications & Purity | 10% in 0.85% sodium chloride and 0.05% sodium azide, aseptically filled |
| Biochemical and Physiological Mechanisms | Human serum albumin (HSA) plays a vital role in the regulation of the colloidal osmotic pressure of blood. It also aids in the maintenance of metal ion homeostasis, including the transport and storage of transition metals. The high binding capacity of HSA |
Storage and Shipping
| Concentration | 10% in 0.85% sodium chloride and 0.05% sodium azide, aseptically filled |
|---|---|
| Storage Temp | Store at 2-8°C |
| Shipped In | Wet ice |
| CAS | 70024-90-7 |
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Citations of This Product
| 1. Bei Kang, Haobo Wang, Huaqing Jing, Yunsheng Dou, Sona Krizkova, Zbynek Heger, Vojtech Adam, Nan Li. (2024) “Golgi-customized Trojan horse” nanodiamonds impair GLUT1 plasma membrane localization and inhibit tumor glycolysis. JOURNAL OF CONTROLLED RELEASE, 371 (338). |
| 2. Yan Xu, Weitao Yang, Zhuoyao Wu, Hui Wang, Tianming Cui, Weiwei Zeng, Yanjing Yun, Bingbo Zhang. (2024) A Chromium-Based magnetic resonance probe for in situ gastric pH imaging. CHEMICAL ENGINEERING JOURNAL, (154269). |
| 3. Jintao Liang, Shuaikang Dong, Xiaohong Tan, Junyan Gong, Xuyang Chen, Zhide Zhou, Guiyin Li. (2025) A high-sensitivity label-free electrochemical aptasensor for point-of-care measurements of low-density lipoprotein in plasma based on aptamer and MXene-CMCS-Hemin nanocomposites. BIOELECTROCHEMISTRY, (108972). |
| 4. Ting Yang, Zihan Liu, Zixuan Fu, Xiaojie Zhang, Yongjin Cao, Qiangwei Liang, Jiale Miao, Hao Yang, Tong Zhang, Jing Hei, Weiqing Ni, Yanhua Liu. (2024) Albumin nanoassembly bi-directionally manipulated ferroptosis in tumor and CD8+ T cells for triple-negative breast cancer therapy. Asian Journal of Pharmaceutical Sciences, (100970). |
| 5. Xiaohui Meng, Zhangchen Xia, Junwen Cheng, Yanbin Wang, Xueyong Ren, Liang He, Dan Liu. (2025) Assessment of the binding mechanism of ergothioneine to human serum albumin: Multi-spectroscopy, molecular docking and molecular dynamic simulation. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 327 (125368). |
| 6. Mingguo Peng, Yang Xu, Yao Wu, Xuewen Cai, Weihua Zhang, Lu Zheng, Erdeng Du, Jiajun Fu. (2024) Binding Affinity and Mechanism of Six PFAS with Human Serum Albumin: Insights from Multi-Spectroscopy, DFT and Molecular Dynamics Approaches. Toxics, 12 (1): (43). |
| 7. Guiyin Li, Bo Wang, Shengnan Li, Xinhao Li, Ruijie Yan, Xiaohong Tan, Jintao Liang, Zhide Zhou. (2024) Competitive electrochemical aptasensor for high sensitivity detection of liver cancer marker GP73 based on rGO-Fc-PANi nanocomposites. BIOELECTROCHEMISTRY, 160 (108767). |
| 8. Zhiheng Zhang, Baicun Chen, Qianzhu Lin, Xiaojing Li, Huang Zhang, David Julian McClements, Zhengyu Jin, Chao Qiu. (2025) Cyclodextrin regulates the binding of quercetin to plasma proteins: Potentially enhancing bioavailability and efficacy. Food Bioscience, 63 (105770). |
| 9. Qinglian Liu, Jianglin Wu, Jiajia Zhang, Fuan Wang, Zhongwei Jiang, Yi Wang, Xue Gong, Pu Zhang. (2025) Harnessing a Self-Regenerated Hybridization Circuit for Differentiating Heart Failure Patients of Varied Severity. Small, (2408384). |
| 10. Liang Jintao, Yu Tingting, Tan Xiaohong, Jiang Lizhi, He Wei, Zhan Yulian, Huang Yong, Zhou Zhide, Li Guiyin. (2025) High-Precision Fluorescence Platform for Point-of-Care Measurements of Low-Density Lipoprotein Based on Nitrogen, Sulfur-Doped Graphene Quantum Dots and Ferric Tetroxide @ Reduced Graphene Oxide. BioNanoScience, 15 (1): (1-14). |
| 11. Guobin Huang, Qian Xie, Jinxin Chi, Chenchen Lin, Xucong Lin, Zenghong Xie. (2024) Magneto-fluorescent nanobiosensor with tetrahedral framework nucleic acid-confined aptamer for trace adenosine triphosphate detection. SENSORS AND ACTUATORS B-CHEMICAL, 417 (136129). |
| 12. Yu Chen, Zhentan Lu, Dong Wang. (2024) Multifunctional Nanoplatform for Single NIR Laser-Regulated Efficient PDT/PTT/Chemotherapy. BIOMACROMOLECULES, 25 (2): (1038-1046). |
| 13. Wenli Zhu, Miao Hu, Guanghua Su, Weifang Jiang, Hancong Du, Kaxi Chen, Jinfang Nie, Lang Zhang, Xuehui Tang, Yun Zhang. (2025) Nanoprobe-free nanosensor with Tyndall-effect readout for colorimetric detection of alkaline phosphatase. MICROCHEMICAL JOURNAL, 212 (113295). |
| 14. Wang Jihong, Zhang Min, Yang Yunchu, Dai Gaole, Pan Qiubo, Kong Yuan, Zhou Bo, Dong Haolu, Qu Yixiao, Ma Zhengyuan, Fang Haiping, He Hui, Liu Zheng, Wang Jun, Chen Ruoyang. (2024) One-step detection of multi-pollutants with different sizes in water by using cellulose-based composites. CELLULOSE, (1-12). |
| 15. Wang Xingyi, Fang Hanyi, Hu Wenzhu, Feng Yuan, Zhou Zhangyongxue, Hu Mengyan, Jiang Dawei, Zhang Yongxue, Lan Xiaoli. (2025) Oxygen-delivery nanoparticles enhanced immunotherapy efficacy monitored by granzyme B PET imaging in malignant tumors. JOURNAL OF NANOBIOTECHNOLOGY, 23 (1): (1-15). |
| 16. Jiamin Huang, Hong Zhao, Xinlian Chen, Tianran Lin, Li Hou, Shulin Zhao. (2025) Pt nanoparticles functionalized hydrogen-bonded organic frameworks: A three-in-one nanozyme for colorimetric detection of alkaline phosphatase. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 333 (125894). |
| 17. Lin Yang, Tingwang Guo, Bin Yao, Gang Chen. (2025) Silver amplified enzyme-free colorimetric immunoassay via graphene oxide as AgNPs carrier for sensitive detection of cancer biomarker. MICROCHEMICAL JOURNAL, (112795). |
| 18. Sijun Huang, Liqiang Yu, Kun Zhang, Jiachen Lv, Henglong Xiang, Dongwei Zhu, Huan Li, Shuning Zhang, Xinyu Liu, Ying Wang, Yi Guo, Li Xu. (2025) Tailored protein corona behavior in titanium dioxide nanosheet fluorescence biosensor for protein quantification assays. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 683 (106). |
| 19. Zhijun Miao, Xue Song, Anan Xu, Chang Yao, Peng Li, Yanan Li, Tao Yang, Gang Shen. (2024) Targeted Delivery of STING Agonist via Albumin Nanoreactor Boosts Immunotherapeutic Efficacy against Aggressive Cancers. Pharmaceutics, 16 (9): (1216). |
| 20. Zhiqiang Jia, Dini Lin, Chengxuan Tang, Xiaoliang Sun, Lingling Cao, Liangle Liu. (2024) Zinc-loaded human serum albumin methacryloyl microspheres with growth factors release for infected wound healing. MATERIALS & DESIGN, 239 (112810). |
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