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AdipoRon hydrochloride - ≥98%(HPLC), high purity , CAS No.1781835-20-8

COA

Grade & Purity:

≥98%(HPLC)

Cas Number: 1781835-20-8
Molecular Weight: 464.98
PubChem CID: 78243714
PubChem SID: 504772421

In stock

Item Number

A287846

Grouped product items
SKU	Size	Availability	Price
A287846-5mg	5mg	3	$138.90
A287846-10mg	10mg	3	$213.90
A287846-25mg	25mg	3	$480.90
A287846-50mg	50mg	3	$881.90
A287846-100mg	100mg	2	$1,586.90

Orally active AdipoR1 and AdipoR2 agonist; antidiabetic

View related series

Adiponectin Receptor (5) Lipid metabolism (1912) Metabolic Enzyme/Protease (4860)

Basic Description

Synonyms	2-(4-Benzyoylphenoxy)-N-[1-(phenylmethyl)-4-piperidinyl]acetamide hydrochloride
Specifications & Purity	≥98%(HPLC)
Biochemical and Physiological Mechanisms	Agonist of adiponectin receptors AdipoR1 and AdipoR2 (Kdvalues are 1.8 and 3.1μM respectively). Activates AMPK and PPARαsignaling; ameliorates insulin resistance, dyslipidemia and glucose intolerance indb/dbmice. Orally active antidiabetic agent.
Storage Temp	Store at -20°C,Desiccated
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - Class Benzene and substituted derivatives
    - Subclass Benzophenones

Kingdom	Organic compounds
Superclass	Benzenoids
Class	Benzene and substituted derivatives
Subclass	Benzophenones
Intermediate Tree Nodes	Not available
Direct Parent	Benzophenones
Alternative Parents	N-benzylpiperidines Diphenylmethanes Aryl-phenylketones Phenylmethylamines Phenoxy compounds Phenol ethers Benzylamines Benzoyl derivatives Alkyl aryl ethers Aralkylamines Trialkylamines Secondary carboxylic acid amides Amino acids and derivatives Azacyclic compounds Hydrocarbon derivatives Hydrochlorides Organic oxides
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	Benzophenone - Aryl-phenylketone - Diphenylmethane - N-benzylpiperidine - Benzylpiperidine - Phenoxy compound - Benzoyl - Benzylamine - Phenol ether - Phenylmethylamine - Aryl ketone - Alkyl aryl ether - Aralkylamine - Piperidine - Tertiary amine - Secondary carboxylic acid amide - Tertiary aliphatic amine - Amino acid or derivatives - Carboxamide group - Ketone - Organoheterocyclic compound - Azacycle - Ether - Carboxylic acid derivative - Amine - Hydrocarbon derivative - Organonitrogen compound - Carbonyl group - Organic oxide - Organic oxygen compound - Organic nitrogen compound - Organooxygen compound - Hydrochloride - Aromatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as benzophenones. These are organic compounds containing a ketone attached to two phenyl groups.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

Pubchem Sid	504772421
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504772421
IUPAC Name	2-(4-benzoylphenoxy)-N-(1-benzylpiperidin-4-yl)acetamide;hydrochloride
INCHI	InChI=1S/C27H28N2O3.ClH/c30-26(28-24-15-17-29(18-16-24)19-21-7-3-1-4-8-21)20-32-25-13-11-23(12-14-25)27(31)22-9-5-2-6-10-22;/h1-14,24H,15-20H2,(H,28,30);1H
InChIKey	TZVJQEGKRLDTHQ-UHFFFAOYSA-N
Smiles	C1CN(CCC1NC(=O)COC2=CC=C(C=C2)C(=O)C3=CC=CC=C3)CC4=CC=CC=C4.Cl
Isomeric SMILES	C1CN(CCC1NC(=O)COC2=CC=C(C=C2)C(=O)C3=CC=CC=C3)CC4=CC=CC=C4.Cl
Molecular Weight	464.98
Reaxy-Rn	58435054
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=58435054&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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8 results found

Lot Number	Certificate Type	Date	Item
H2223088	Certificate of Analysis	Jun 09, 2025	A287846
H2223087	Certificate of Analysis	Jun 09, 2025	A287846
H2223089	Certificate of Analysis	Jun 09, 2025	A287846
G2226166	Certificate of Analysis	May 09, 2025	A287846
G2226015	Certificate of Analysis	May 09, 2025	A287846
G2226018	Certificate of Analysis	May 09, 2025	A287846
G2226019	Certificate of Analysis	May 09, 2025	A287846
G2226020	Certificate of Analysis	May 09, 2025	A287846

Chemical and Physical Properties

Solubility	Solvent:DMSO, Max Conc. mg/mL: 46.5, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 4.65, Max Conc. mM: 10
Molecular Weight	465.000 g/mol
XLogP3
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	8
Exact Mass	464.187 Da
Monoisotopic Mass	464.187 Da
Topological Polar Surface Area	58.600 Å²
Heavy Atom Count	33
Formal Charge	0
Complexity	582.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	2

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