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Acetyl-11-keto-β-Boswellic Acid - ≥98%, high purity , CAS No.67416-61-9

1 Citations COA COA
In stock
Item Number
A329474
Grouped product items
SKU Size
Availability
 Price Qty
A329474-5mg
5mg
3
$72.90
A329474-25mg
25mg
3
$176.90
A329474-100mg
100mg
4
$416.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

a 5-LO and topo I and II inhibitor

View related series
Glucose Metabolism (1943) HIF/HIF Prolyl-Hydroxylase (128) Immunology/Inflammation (1929) Metabolic Enzyme/Protease (4860) Metabolite (5307) NF-κB (747) Reactive Oxygen Species (309)

Basic Description

Synonyms ACETYL-11-OXO-beta-BOSWELLIC ACID | AKBA cpd | 3-Acetyl-11-keto-.beta.-boswellic acid | 3alpha-acetoxy-11-keto-beta-boswellic acid | 3-O-Acetyl-11-keto-b-boswellic acid | FS-1494 | DTXSID601303401 | H-D-Phg(4-Br)-(C#CH2)OH | 3alpha-Acetyl-11-keto-beta-bos
Specifications & Purity Moligand™, ≥98%
Biochemical and Physiological Mechanisms Acetyl-11 keto group- β- Mastic acid (AKBA) has antibacterial and biofilm activity against Staphylococcus epidermidis and Staphylococcus aureus, respectively. It is an activator of nuclear factor E2 related factor (Nrf2) and has neuroprotective properties
Source Boswellia serrata
Storage Temp Store at 2-8°C
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Grade Moligand™
Product Description

AKBA (Acetyl-11-keto-β-boswellic acid) is an active triterpenoid compound from the extract of Boswellia serrate and a novel Nrf2 activator.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Lipids and lipid-like molecules
Class Prenol lipids
Subclass Triterpenoids
Intermediate Tree Nodes Not available
Direct Parent Triterpenoids
Alternative Parents Hydroxysteroids  Cyclohexenones  Dicarboxylic acids and derivatives  Carboxylic acid esters  Carboxylic acids  Organic oxides  Hydrocarbon derivatives  
Molecular Framework Aliphatic homopolycyclic compounds
Substituents Triterpenoid - 15-hydroxysteroid - Hydroxysteroid - Steroid - Cyclohexenone - Dicarboxylic acid or derivatives - Carboxylic acid ester - Ketone - Carboxylic acid derivative - Carboxylic acid - Organic oxide - Carbonyl group - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Aliphatic homopolycyclic compound
Description This compound belongs to the class of organic compounds known as triterpenoids. These are terpene molecules containing six isoprene units.
External Descriptors Not available

Product Properties

pKa pKa: 4.28 (Predicted)

Associated Targets(Human)

ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALOX15B Tchem Arachidonate 15-lipoxygenase, type II (7244 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KDR Tclin Vascular endothelial growth factor receptor 2 (20924 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PIN1 Tchem Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (36611 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Caco-2 (12174 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
COLO 205 (50209 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
DU-145 (51482 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HL-60 (67320 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HT-29 (80576 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MCF7 (126967 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PC-3 (62116 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HEp-2 (3859 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
A2780 (11979 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HUVEC (11049 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
LNCaP (8286 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HeLa (62764 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SW-620 (52400 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PBMC (10003 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Hsd11b1 11-beta-hydroxysteroid dehydrogenase 1 (202 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PTGES Prostaglandin E synthase (10 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PREP Prolyl endopeptidase (14 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Hsd11b2 11-beta-hydroxysteroid dehydrogenase 2 (82 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mus musculus (284745 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
RAW264.7 (28094 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Brain (1 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Plasma (328 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

Pubchem Sid 504766105
Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504766105
IUPAC Name (3R,4R,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bS)-3-acetyloxy-4,6a,6b,8a,11,12,14b-heptamethyl-14-oxo-1,2,3,4a,5,6,7,8,9,10,11,12,12a,14a-tetradecahydropicene-4-carboxylic acid
INCHI InChI=1S/C32H48O5/c1-18-9-12-28(4)15-16-30(6)21(25(28)19(18)2)17-22(34)26-29(5)13-11-24(37-20(3)33)32(8,27(35)36)23(29)10-14-31(26,30)7/h17-19,23-26H,9-16H2,1-8H3,(H,35,36)/t18-,19+,23-,24-,25+,26-,28-,29+,30-,31-,32-/m1/s1
InChIKey HMMGKOVEOFBCAU-BCDBGHSCSA-N
Smiles CC1CCC2(CCC3(C(=CC(=O)C4C3(CCC5C4(CCC(C5(C)C(=O)O)OC(=O)C)C)C)C2C1C)C)C
Isomeric SMILES C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC(=O)[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@H]([C@]5(C)C(=O)O)OC(=O)C)C)C)[C@@H]2[C@H]1C)C)C
WGK Germany 3
Molecular Weight 512.74
Reaxy-Rn 25999391
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25999391&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

7 results found

Lot Number Certificate Type Date Item
E2327746 Certificate of Analysis Apr 27, 2023 A329474
B2506018 Certificate of Analysis Apr 27, 2023 A329474
E2327745 Certificate of Analysis Apr 27, 2023 A329474
E2327741 Certificate of Analysis Apr 27, 2023 A329474
E2327747 Certificate of Analysis Apr 27, 2023 A329474
E2327748 Certificate of Analysis Apr 27, 2023 A329474
E2327749 Certificate of Analysis Apr 27, 2023 A329474

Chemical and Physical Properties

Solubility Soluble in chloroform, alcohol, DMSO (10 mg/ml), acetone, dichloromethane, and diethyl ether.
Refractive Index n20D1.55 (Predicted)
Boil Point(°C) 600.29° C at 760 mmHg (Predicted)
Molecular Weight 512.700 g/mol
XLogP3 7.200
Hydrogen Bond Donor Count 1
Hydrogen Bond Acceptor Count 5
Rotatable Bond Count 3
Exact Mass 512.35 Da
Monoisotopic Mass 512.35 Da
Topological Polar Surface Area 80.700 Ų
Heavy Atom Count 37
Formal Charge 0
Complexity 1060.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 11
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Alternative Products

  1. Acetyl-11-keto-β-Boswellic Acid, Boswellia serrata
    Acetyl-11-keto-β-Boswellic Acid, Boswellia serrata
    • 10mM in DMSO

    Starting at $132.90

Citations of This Product

How to Cite Aladdin Scientific Products?
1. Aiwen Shi, Bin Qi, Xiaolei Tang, Li Liu, Chang Wang, Ziyi Jia.  (2025)  Qualitative and quantitative analysis of the changes in chemical composition of frankincense before and after stir-frying using GC-MS and LC-MS.  Analytical Methods,     

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