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Acesulfame K - 98%, high purity , CAS No.55589-62-3

3 Citations COA COA
In stock
Item Number
A113942
Grouped product items
SKU Size
Availability
 Price Qty
A113942-25g
25g
4
$13.90
A113942-100g
100g
9
$27.90
A113942-500g
500g
1
$69.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Synthetic sweetener.

View related series
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Basic Description

Synonyms 4-(1H-Tetrazol-1-yl)benzoic acid, AldrichCPR | INS-950 | 1-Phenyl-3-(pyridin-3-yl)urea | Acesulfame potassium, European Pharmacopoeia (EP) Reference Standard | AKOS001874366 | NCGC00259972-01 | AKOS016015051 | AMY13647 | Acesulfame potassium (NF) | FT-062
Specifications & Purity Moligand™, ≥98%
Biochemical and Physiological Mechanisms Heat-stable synthetic sweetener. Allelic variation of the Tas1r3 gene affects behavioral taste responses to this molecule, suggesting that it is a T1R3 receptor ligand.
Storage Temp Room temperature
Shipped In Normal
Grade Moligand™
Product Description

Acesulfame potassium is a synthetic sweetener. Long-term use of Acesulfame potassium can affect cognitive function, possibly by altering the neurometabolic functions in mice. Acesulfame potassium can suppress autophagic degradation of PD-L1 in RIL-175 and SK-Hep1 cells through the ERK1/2-mTORC1-ULK1 pathway, which may be related to immune evasion in cancer cells. Acesulfame potassium can be used in research on neurological diseases, metabolic disorders, cancer, and immune evasion.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organic acids and derivatives
Class Organic sulfuric acids and derivatives
Subclass Not available
Intermediate Tree Nodes Not available
Direct Parent Organic sulfuric acids and derivatives
Alternative Parents Oxacyclic compounds  Carboxylic acids and derivatives  Carbene-type 1,3-dipolar compounds  Azacyclic compounds  Organopnictogen compounds  Organonitrogen compounds  Organic potassium salts  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular Framework Aliphatic heteromonocyclic compounds
Substituents Organic sulfuric acid or derivatives - Carboxylic acid derivative - Carbene-type 1,3-dipolar compound - Organic 1,3-dipolar compound - Organoheterocyclic compound - Organic alkali metal salt - Azacycle - Oxacycle - Organic potassium salt - Organic nitrogen compound - Organic salt - Organonitrogen compound - Organooxygen compound - Carbonyl group - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Aliphatic heteromonocyclic compound
Description This compound belongs to the class of organic compounds known as organic sulfuric acids and derivatives. These are organic compounds containing the sulfuric acid or a derivative thereof.
External Descriptors Not available

Associated Targets(Human)

CA2 Tclin Carbonic anhydrase II (17698 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
VDR Tclin Vitamin D receptor (26531 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CXCL8 Tchem Interleukin-8 (642 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CA1 Tclin Carbonic anhydrase I (13240 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CA12 Tclin Carbonic anhydrase XII (6231 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CA9 Tclin Carbonic anhydrase IX (8255 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TP53 Tchem Cellular tumor antigen p53 (48468 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Lymphoblastoid cell (5959 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KMT2A Tchem Histone-lysine N-methyltransferase MLL (17327 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TAS2R31 Tchem Taste receptor type 2 member 31 (86 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TAS2R14 Tchem Taste receptor type 2 member 14 (240 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TAS2R16 Tchem Taste receptor type 2 member 16 (102 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TAS2R4 Tchem Taste receptor type 2 member 4 (14 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TAS2R41 Tchem Taste receptor type 2 member 41 (57 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TAS2R60 Tchem Taste receptor type 2 member 60 (8 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TAS2R9 Tchem Taste receptor type 2 member 9 (14 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TAS2R10 Tchem Taste receptor type 2 member 10 (51 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TAS2R20 Tchem Taste receptor type 2 member 20 (10 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TAS2R50 Tchem Taste receptor type 2 member 50 (12 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TAS2R8 Tchem Taste receptor type 2 member 8 (387 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TAS2R38 Tchem Taste receptor type 2 member 38 (37 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TAS2R39 Tchem Taste receptor type 2 member 39 (48 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TAS2R40 Tchem Taste receptor type 2 member 40 (10 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TAS2R43 Tchem Taste receptor type 2 member 43 (15 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TAS2R45 Tchem Taste receptor type 2 member 45 (8 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TAS2R46 Tchem Taste receptor type 2 member 46 (155 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TAS2R30 Tchem Taste receptor type 2 member 30 (12 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TAS2R19 Tchem Taste receptor type 2 member 19 (20 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TAS2R42 Tchem Taste receptor type 2 member 42 (6 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TAS2R13 Tchem Taste receptor type 2 member 13 (13 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TAS2R7 Tchem Taste receptor type 2 member 7 (31 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TAS2R5 Tchem Taste receptor type 2 member 5 (11 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TAS2R3 Tchem Taste receptor type 2 member 3 (12 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Mus musculus (284745 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

Pubchem Sid 488197130
Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488197130
IUPAC Name potassium;6-methyl-2,2-dioxo-1-oxa-2λ6-thia-3-azanidacyclohex-5-en-4-one
INCHI InChI=1S/C4H5NO4S.K/c1-3-2-4(6)5-10(7,8)9-3;/h2H,1H3,(H,5,6);/q;+1/p-1
InChIKey WBZFUFAFFUEMEI-UHFFFAOYSA-M
Smiles CC1=CC(=O)[N-]S(=O)(=O)O1.[K+]
Isomeric SMILES CC1=CC(=O)[N-]S(=O)(=O)O1.[K+]
WGK Germany 1
Alternate CAS 33665-90-6
Molecular Weight 201.24
Beilstein 3637857
Reaxy-Rn 3637857
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3637857&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

17 results found

Lot Number Certificate Type Date Item
E2515121 Certificate of Analysis Apr 27, 2025 A113942
E2515122 Certificate of Analysis Apr 27, 2025 A113942
E2515139 Certificate of Analysis Apr 27, 2025 A113942
I2412149 Certificate of Analysis Jul 27, 2024 A113942
I2412156 Certificate of Analysis Jul 27, 2024 A113942
I2412157 Certificate of Analysis Jul 27, 2024 A113942
I2412162 Certificate of Analysis Jul 27, 2024 A113942
G2204058 Certificate of Analysis Jul 07, 2022 A113942
G2204059 Certificate of Analysis Jul 06, 2022 A113942
B2327256 Certificate of Analysis Jun 23, 2022 A113942
I2201060 Certificate of Analysis Jun 23, 2022 A113942
I2201062 Certificate of Analysis Jun 23, 2022 A113942
I2201069 Certificate of Analysis Jun 23, 2022 A113942
K2329239 Certificate of Analysis Jun 23, 2022 A113942
H1401038 Certificate of Analysis May 06, 2022 A113942
E1821024 Certificate of Analysis Apr 02, 2022 A113942
E2311303 Certificate of Analysis Apr 02, 2022 A113942

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Chemical and Physical Properties

Solubility Soluble in water
Sensitivity Moisture sensitive
Melt Point(°C) 229-232°C
Molecular Weight 201.240 g/mol
XLogP3
Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 5
Rotatable Bond Count 0
Exact Mass 200.95 Da
Monoisotopic Mass 200.95 Da
Topological Polar Surface Area 69.800 Ų
Heavy Atom Count 11
Formal Charge 0
Complexity 288.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 2

Alternative Products

  1. Acesulfame K
    Acesulfame K

    Starting at $68.90

Citations of This Product

How to Cite Aladdin Scientific Products?
1. Ferry Saputra, Yu-Heng Lai, Rey Arturo T. Fernandez, Allan Patrick G. Macabeo, Hong-Thih Lai, Jong-Chin Huang, Chung-Der Hsiao.  (2021)  Acute and Sub-Chronic Exposure to Artificial Sweeteners at the Highest Environmentally Relevant Concentration Induce Less Cardiovascular Physiology Alterations in Zebrafish Larvae.  Biology-Basel,  10  (6): (548). 
2. Shixian Chen, Gaohui Du, Yan Cheng, Di Han, Jiahao Deng, Yunting Wang, Huayu Li, Libing Yao, Dong Wang, Qingmei Su, Bingshe Xu.  (2025)  Dry-processing of VN quantum dots/N, O, S-doped hierarchical porous carbon electrodes with high sulfur-loading for practical lithium-sulfur batteries.  CHEMICAL ENGINEERING JOURNAL,  509  (161440). 
3. Wenjiao Liu, Han wang, Qi Mu, Ting Gong.  (2024)  Taste receptor T1R3 regulates testosterone synthesis via the cAMP-PKA-SP1 pathway in testicular Leydig cells.  THERIOGENOLOGY,     

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