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Ac-VLPE-FMK , CAS No.2679825-27-3

COA

Cas Number: 2679825-27-3
Molecular Weight: 528.61

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Item Number

A648229

Grouped product items
SKU	Size	Availability	Price
A648229-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$188.90
A648229-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$414.90
A648229-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$663.90

View related series

Amino Acid/Protein Metabolism (1836) Cathepsin (64) Metabolic Enzyme/Protease (4860)

Basic Description

Biochemical and Physiological Mechanisms	Ac-VLPE-FMK, a tetrapeptidyl mono-fluoromethyl ketone (m-FMK), is a Cat-B and Cat-L inhibitor. Ac-VLPE-FMK can be used for the research of cancer aggressiveness.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Ac-VLPE-FMK, a tetrapeptidyl mono-fluoromethyl ketone (m-FMK), is a Cat-B and Cat-L inhibitor. Ac-VLPE-FMK can be used for the research of cancer aggressiveness In Vitro Ac-VLPE-FMK (2 μM) significantly affects the cleavage of probe Ac-PLVQ-AMC by human recombinant CtsB and L. Ac-VLPE-FMK (30 min) inhibits the generation of the fluorescence derived from the cleavage of the substrate Ac-PLVQ-AMC in 769-p and A498 cells. Ac-VLPE-FMK (2.5-250 μM; 24-72 h) does not affect renal cancer cell viability, but influences cell migration rate, cellular adhesion, colony formation, and markers expression in renal cancer cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:Cathepsin B cathepsin L

Names and Identifiers

Smiles	O=C(N(CCC1)[C@@H]1C(N[C@H](C(CF)=O)CCC(OC)=O)=O)[C@H](CC(C)C)NC([C@H](C(C)C)NC(C)=O)=O
Molecular Weight	528.61

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