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α-Mannosidase from Canavalia ensiformis (Jack bean), CAS No.9025-42-7

COA COA
    Grade & Purity:
  • ammonium sulfate suspension,≥15 units/mg protein (biuret)
In stock
Item Number
M755138
Grouped product items
SKU Size
Availability
 Price Qty
M755138-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$144.90
M755138-5mg
5mg
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Production requires sourcing of materials. We appreciate your patience and understanding.
$522.90
M755138-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,007.90
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View related series
Glucose Metabolism (1943)

Basic Description

Product Name α-Mannosidase from Canavalia ensiformis (Jack bean), CAS No.9025-42-7
Product Description

α−Mannosidase from Canavalia ensiformis is a tretamer composed of two subunits that each contain two components at 44 and 66 kDa.
α-Mannosidase is an exo-glycosidase and an inc metalloenzyme.
Lysosomal α-mannosidases are class II mannosidases that belong to glycoside hydrolase family 38 and play an important role in the degradation of asparagine-linked carbohydrates of glycoproteins.
Application:
α-Mannosidase can be used to liberate mannose from a variety of synthetic and natural α-mannosides. It has also been used in a study to investigate the causes of neurodegeneration in mucolipidosis II ′knock-in′ mice.
α-Mannosidase from Canavalia ensiformis (Jack bean) has been used:
  • for the digestion of neutral glycans.
  • to remove O-glycans from recombinant β-glucosidase
  • for the inhibition of renal fibroblasts proliferation

Liberates mannose from a variety of synthetic and natural α-mannosides.
Specifications & Purity ammonium sulfate suspension,≥15 units/mg protein (biuret)
Biochemical and Physiological Mechanisms α−Mannosidase has been shown to inhibit the proliferation of B-lymphocytes. α-Mannosidase cleaves near α1−2-, α1−3- and α1−6-linked mannose residues.α-Mannosidase is an acid hydrolase which is located in plant vacuoles and is thought to be involved with t

Taxonomic Classification

Taxonomy Tree

Kingdom Inorganic compounds
Superclass Homogeneous metal compounds
Class Homogeneous transition metal compounds
Subclass Not available
Intermediate Tree Nodes Not available
Direct Parent Homogeneous transition metal compounds
Alternative Parents Not available
Molecular Framework Not available
Substituents Homogeneous transition metal
Description This compound belongs to the class of inorganic compounds known as homogeneous transition metal compounds. These are inorganic compounds containing only metal atoms,with the largest atom being a transition metal atom.
External Descriptors a cation

Associated Targets(Human)

GPR83 Tchem Probable G-protein coupled receptor 83 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
TRPM1 Tchem Transient receptor potential cation channel subfamily M member 1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
TRPM2 Tchem Transient receptor potential cation channel subfamily M member 2 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
GLRA2 Tchem Glycine receptor subunit alpha-2 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
TRPA1 Tclin Transient receptor potential cation channel subfamily A member 1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
CLCN4 Tchem H(+)/Cl(-) exchange transporter 4 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
ADRB2 Tclin Beta-2 adrenergic receptor (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
ASIC3 Tchem Acid-sensing ion channel 3 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
ASIC1 Tchem Acid-sensing ion channel 1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
GLRA1 Tclin Glycine receptor subunit alpha-1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
GLRA3 Tchem Glycine receptor subunit alpha-3 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
GLRB Tclin Glycine receptor subunit beta (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Storage and Shipping

Concentration ammonium sulfate suspension,≥15 units/mg protein (biuret)
Storage Temp Store at 2-8°C
Shipped In Wet ice
CAS 9025-42-7

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

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