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α-Hydroxy-γ-butyrolactone - 99%, high purity , CAS No.19444-84-9

COA

Grade & Purity:

≥99%

Cas Number: 19444-84-9
Molecular Weight: 102.09
Beilstein Registry Number: 80587
MDL number: MFCD00134268
PubChem CID: 545831
PubChem SID: 488190229

In stock

Item Number

H113417

Grouped product items
SKU	Size	Availability	Price
H113417-1g	1g	7	$30.90
H113417-5g	5g	4	$115.90
H113417-10g	10g	2	$177.90
H113417-25g	25g	1	$363.90

View related series

lactone (49) Non heterocyclic block (8163)

Basic Description

Synonyms	3-hydroxydihydrofuran-2-one \| Dihydro-3-hydroxy-2(3H)-furanone \| s8103 \| SY052569 \| 3-Hydroxytetrahydrofuran-2-one \| FT-0605147 \| 2-HYDROXY-.GAMMA.-BUTYROLACTONE, (+/-)- \| Ibrutinib (JAN/USAN) \| DTXSID00941181 \| EC 692-561-9 \| 3-Hydroxydihydro-2(3H)-furan
Specifications & Purity	≥99%
Storage Temp	Store at 2-8°C,Protected from light,Argon charged
Shipped In	Wet ice This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	α-Hydroxy-γ-butyrolactone is used to initiate the synthesis of enantiomerically pure orthogonally protected δ-azaproline, via Mitsunobu reaction. α-Hydroxy-γ-butyrolactone is a 5-membered cyclic ester. It was obtained via tin-conversion of biomass-derived 1,3-dihydroxyacetone (DHA) and formaldehyde. Used to initiate the synthesis of series of seco-pseudonucleoside synthons via aminolysis.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Lactones
    - Subclass Gamma butyrolactones

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Lactones
Subclass	Gamma butyrolactones
Intermediate Tree Nodes	Not available
Direct Parent	Gamma butyrolactones
Alternative Parents	Tetrahydrofurans Secondary alcohols Carboxylic acid esters Oxacyclic compounds Monocarboxylic acids and derivatives Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aliphatic heteromonocyclic compounds
Substituents	Gamma butyrolactone - Tetrahydrofuran - Secondary alcohol - Carboxylic acid ester - Oxacycle - Monocarboxylic acid or derivatives - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Alcohol - Aliphatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as gamma butyrolactones. These are compounds containing a gamma butyrolactone moiety, which consists of an aliphatic five-member ring with four carbon atoms, one oxygen atom, and bears a ketone group on the carbon adjacent to the oxygen atom.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

Pubchem Sid	488190229
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488190229
IUPAC Name	3-hydroxyoxolan-2-one
INCHI	InChI=1S/C4H6O3/c5-3-1-2-7-4(3)6/h3,5H,1-2H2
InChIKey	FWIBCWKHNZBDLS-UHFFFAOYSA-N
Smiles	C1COC(=O)C1O
Isomeric SMILES	C1COC(=O)C1O
WGK Germany	3
Molecular Weight	102.09
Beilstein	80587
Reaxy-Rn	80587
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=80587&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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11 results found

Lot Number	Certificate Type	Date	Item
D2021079	Certificate of Analysis	Feb 21, 2024	H113417
F23131060	Certificate of Analysis	May 26, 2023	H113417
F23131063	Certificate of Analysis	May 26, 2023	H113417
F23131056	Certificate of Analysis	May 26, 2023	H113417
F23131059	Certificate of Analysis	May 26, 2023	H113417
F23131061	Certificate of Analysis	May 26, 2023	H113417
F23131057	Certificate of Analysis	May 26, 2023	H113417
F23131226	Certificate of Analysis	May 26, 2023	H113417
F23131058	Certificate of Analysis	May 26, 2023	H113417
F2411048	Certificate of Analysis	May 26, 2023	H113417
C23101245	Certificate of Analysis	Mar 17, 2023	H113417

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Chemical and Physical Properties

Sensitivity	Moisture sensitive.Light sensitive
Refractive Index	1.476-1.481
Flash Point(°F)	113 °C
Flash Point(°C)	113°C
Boil Point(°C)	133 °C/10 mmHg
Molecular Weight	102.090 g/mol
XLogP3	-0.400
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	0
Exact Mass	102.032 Da
Monoisotopic Mass	102.032 Da
Topological Polar Surface Area	46.500 Å²
Heavy Atom Count	7
Formal Charge	0
Complexity	88.900
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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