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Basic Description
| Product Name | α-helical CRF 9-41, CAS No.90880-23-2 |
|---|---|
| Synonyms | α-helical-Corticotropin-Releasing Factor 9-41 |
| Product Description |
Alpha-helical CRF(9-41) is a competitive CRF2 receptor antagonist with a KB of about 100 nM. Alpha-helical CRF(9-41) is also a partial agonist of the CRF1 receptor with an EC50 of 140 nM Biological activity: Biological Activity for α-helical CRF 9-41 α-helical CRF 9-41 is a corticotropin-releasing factor receptor antagonist (Ki values are 17, 5 and 0.97 at human CRF1, rat CRF2α and mouse CRF2β receptors respectively). |
| Specifications & Purity | ≥98% |
| Biochemical and Physiological Mechanisms | Corticotropin-releasing factor receptor antagonist (Kivalues are 17, 5 and 0.97 at human CRF1, rat CRF2αand mouse CRF2βreceptors respectively). |
| Sequence | DLTFHLLREMLEMAKAEQEAEQAALNRLLLEEA(Modifications: Ala-33 = C-terminal amide) |
Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Storage and Shipping
| Storage Temp | Store at -20°C,Desiccated |
|---|---|
| Shipped In | Ice chest + Ice pads |
| CAS | 90880-23-2 |
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 L2319339 |
Certificate of Analysis | Dec 06, 2023 | H287574 |
| L2319351 |
Certificate of Analysis | Dec 06, 2023 | H287574 |
| L2319331 |
Certificate of Analysis | Dec 06, 2023 | H287574 |
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