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Basic Description
| Synonyms | alpha-D-glucose | alpha-D-Glucopyranose | 492-62-6 | alpha-glucose | alpha-Dextrose | Glucopyranose, alpha-D- | a-Dextrose | (2S,3R,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol | a-D-Glucose | alpha-D-Glc | CHEBI:17925 | (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran |
|---|---|
| Specifications & Purity | 10mM in DMSO |
| Storage Temp | Store at -80°C |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Product Description |
Application α-D-Glucose is used: ·As a reducing agent in the preparation superparamagnetic ferrous oxide (Fe3O4) nanoparticles and silver nanocrystals. ·As an additive for the formation of isoporous polystyrene-block-poly(4-vinylpyridine) (PS-b-P4VP) diblock copolymer membranes. ·For glycosylation of cell-penetrating poly(disulfide)s (CPDs) with improved solubility to achieve multifunctional cellular uptake. ·As a precursor in the synthesis of metal/carbon nanohybrids under hydrothermal conditions. |
Taxonomic Classification
Taxonomy Tree
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Kingdom
Organic compounds
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Superclass
Organic oxygen compounds
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Class
Organooxygen compounds
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Subclass
Carbohydrates and carbohydrate conjugates
- Level5 Monosaccharides
- Level6 Hexoses
- Level5 Monosaccharides
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Subclass
Carbohydrates and carbohydrate conjugates
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Class
Organooxygen compounds
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Superclass
Organic oxygen compounds
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic oxygen compounds |
| Class | Organooxygen compounds |
| Subclass | Carbohydrates and carbohydrate conjugates |
| Intermediate Tree Nodes | Monosaccharides |
| Direct Parent | Hexoses |
| Alternative Parents | Oxanes Secondary alcohols Hemiacetals Polyols Oxacyclic compounds Primary alcohols Hydrocarbon derivatives |
| Molecular Framework | Aliphatic heteromonocyclic compounds |
| Substituents | Hexose monosaccharide - Oxane - Secondary alcohol - Hemiacetal - Oxacycle - Organoheterocyclic compound - Polyol - Hydrocarbon derivative - Primary alcohol - Alcohol - Aliphatic heteromonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as hexoses. These are monosaccharides in which the sugar unit is a is a six-carbon containing moeity. |
| External Descriptors | D-glucopyranose |
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Associated Targets(Human)
PYGM
Tchem
Muscle glycogen phosphorylase (197 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Associated Targets(non-human)
Pygl
Liver glycogen phosphorylase (81 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Hdac6
Histone deacetylase 6 (222 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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3T3-L1 (3664 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Calf thymus DNA (4845 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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PYGM
Glycogen phosphorylase, muscle form (1331 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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rep
Replicase polyprotein 1ab (378 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Names and Identifiers
| IUPAC Name | (2S,3R,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol |
|---|---|
| INCHI | InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1 |
| InChIKey | WQZGKKKJIJFFOK-DVKNGEFBSA-N |
| Smiles | C(C1C(C(C(C(O1)O)O)O)O)O |
| Isomeric SMILES | C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O |
| WGK Germany | 3 |
| Molecular Weight | 180.16 |
| Reaxy-Rn | 1907357 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1907357&ln= |
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
| Sensitivity | Moisture sensitive. |
|---|---|
| Specific Rotation[α] | [α]20/D +52°, c = 10 in H2O |
| Melt Point(°C) | 153-156 °C |
| Molecular Weight | 180.160 g/mol |
| XLogP3 | -2.600 |
| Hydrogen Bond Donor Count | 5 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 1 |
| Exact Mass | 180.063 Da |
| Monoisotopic Mass | 180.063 Da |
| Topological Polar Surface Area | 110.000 Ų |
| Heavy Atom Count | 12 |
| Formal Charge | 0 |
| Complexity | 151.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 5 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
Citations of This Product
| 1. Lingling Zhang, Ying Yang, Yongxing Zhu, Haijun Hu, Qie Jia, Chong Sun, Xuedong Zhu, Yiqing Liu. (2024) Antifungal activity and mechanism of chitosan against Fusarium solani caused ginger soft rot during postharvest storage. POSTHARVEST BIOLOGY AND TECHNOLOGY, 208 (112680). |
| 2. Peng Xia, Shilan Li, Long Yuan, Shengdong Jing, Xiaoli Peng, Shengjun Lu, Yufei Zhang, Haosen Fan. (2024) Encapsulating CoRu alloy nanocrystals into nitrogen-doped carbon nanotubes to synergistically modify lithium-sulfur batteries separator. JOURNAL OF MEMBRANE SCIENCE, 694 (122395). |
| 3. Jiansen Lie, Feili Luo, Yafang Liu, Yixuan Yang, Qingling Nie, Xiaochuan Chen, Ruiyun You, Yunzhen Liu, Xiufeng Xiao, Yudong Lu. (2024) Recyclable magnetic nanoparticles combined with TiO2 enrichment and “Off” to “On” SERS assay for sensitive detection of alkaline phosphatase. CHEMICAL ENGINEERING JOURNAL, 479 (147241). |
| 4. Peng-Fang Zhang, Jia-Hui Li, Shao-Jian Zhang, Da-Cheng Li, Su-Yuan Zeng, Shu-Ling Xu, Qing-Xia Yao, Ling-Yang Liu, Lei Ding, Heng-Xiang Li, Yi-Yang Hu, Jun-Tao Li, Yao Zhou. (2023) Toward Shuttle-Free Zn–I2 Battery: Anchoring and Catalyzing Iodine Conversion by High-Density P-Doping Sites in Carbon Host. ADVANCED FUNCTIONAL MATERIALS, (2306359). |
| 5. Lujie Zhang, Xing Liu, Jian Mao, Yangyang Sun, Yanni Gao, Juan Bai, Ping Jiang. (2023) Porcine reproductive and respiratory syndrome virus-mediated lactate facilitates virus replication by targeting MAVS. VETERINARY MICROBIOLOGY, |
| 6. Zhihao Liu, Qixiang Shang, Haimeng Li, Daozheng Fang, Zhuohuan Li, Yuqi Huang, Mimi Zhang, Kam Ming Ko, Jihang Chen. (2023) Exploring the possible mechanism(s) underlying the nephroprotective effect of Zhenwu Decoction in Diabetic Kidney Disease: An Integrated Analysis. PHYTOMEDICINE, (154988). |
| 7. Zhi-Yong Guo, Chen Zhang, Lin-min Chen, Mei-huang Zeng, Qiu-hong Yao, Ting-Xiu Ye, He-zhou Luo, Xiao-mei Chen, Xi Chen. (2023) Design of competition nanoreactor with shell-isolated colloidal plasmonic nanomaterials for quantitative sensor platform. TALANTA, 265 (124861). |
| 8. Qian Wang, Yuzhe Wang, Guiyong Xiao, Xinde Zhu. (2023) Electrophoretic Deposition of Co3O4 Particles/Reduced Graphene Oxide Composites for Efficient Non-Enzymatic H2O2 Sensing. Materials, 16 (3): (1261). |
| 9. Ruizhi Hu, Chen Dai, Xinyue Dai, Caihong Dong, Hui Huang, Xinran Song, Wei Feng, Li Ding, Yu Chen, Bo Zhang. (2023) Topology regulation of nanomedicine for autophagy-augmented ferroptosis and cancer immunotherapy. Science Bulletin, 68 (77). |
| 10. Ruizhi Hu, Chen Dai, Caihong Dong, Li Ding, Hui Huang, Yu Chen, Bo Zhang. (2022) Living Macrophage-Delivered Tetrapod PdH Nanoenzyme for Targeted Atherosclerosis Management by ROS Scavenging, Hydrogen Anti-inflammation, and Autophagy Activation. ACS Nano, 16 (10): (15959–15976). |
| 11. Jingjing Zhao, Jingjing Zhao, Shaohua Lu, Shaohua Lu, Julio Bastos-Arrieta, Julio Bastos-Arrieta, Cristina Palet, Yiling Sun, Renheng Wang, Zhengfang Qian, Shuting Fan. (2022) Enhanced terahertz sensitivity for glucose detection with a hydrogel platform embedded with Au nanoparticles. Biomedical Optics Express, 13 (7): (4021-4031). |
| 12. Shanfu Sun, Ming Zheng, Pengfei Cheng, Fugui Wu, Luping Xu. (2022) Porous bimetallic cobalt-iron phosphide nanofoam for efficient and stable oxygen evolution catalysis. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 626 (515). |
| 13. Yi Wei, Licong Lu, Xudong Zhang, Jianbing Ji. (2022) Hydrogen produced at low temperatures by electrochemically assisted pyrolysis of cellulose in molten carbonate. ENERGY, 254 (124405). |
| 14. Ning Tianxiang, Luo Yinyi, Liu Piao, Lu Anxian. (2022) A novel Ag nanoparticles purification method and the conductive ink based on the purified Ag nanoparticles for printed electronics. JOURNAL OF NANOPARTICLE RESEARCH, 24 (1): (1-18). |
| 15. Qiuting Xu, Jia Lei, Lixi Chen, Jiahui Xu, Guodong Li, Jun Wan, Linfeng He, Yufei Shen, Guangkuo Wei, Guoxun Ji, Duo Zhang, Liang Sun, Shuao Wang. (2024) Biomass-derived ultramicroporous carbon with narrow pore size distribution for record-high radon adsorption. SEPARATION AND PURIFICATION TECHNOLOGY, (126582). |
| 16. Shuaishuai Guo, Guowen Peng, Qingming Zeng, Lulin Guo, Chao Zhang, Qingyan Zhang, Xijun Fu, Junwen Lv, Qingyi Zeng. (2024) Carbon fiber supported and N-doped carbon encapsulated nZVI for synergistically adsorbing and reducing uranium. Journal of Cleaner Production, 448 (141538). |
| 17. Zhihao Liu, Qixiang Shang, Huali Zuo, Haimeng Li, Daozheng Fang, Jiayu Zhang, Hsien-Da Huang, Daniel Granato, Jianping Chen, Jihang Chen. (2024) Cynomorium songaricum: UHPLC/ESI-LTQ-Orbitrap-MS analysis and mechanistic study on insulin sensitivity of a flavonoid-enriched fraction. PHYTOMEDICINE, (155862). |
| 18. Xiaoli Peng, Pengfei Wan, Long Yuan, Shilan Li, Shengdong Jing, Fuyu Xiao, Lingxing Zeng, Yaozhu Tian, Zhu Luo, Haosen Fan. (2025) Duplex core-shell Co@Co9S8@NSC nanocrystals for high-performance lithium-sulfur battery through synergistic capture-catalysis-conversion of polysulfide. JOURNAL OF POWER SOURCES, 631 (236310). |
| 19. Qiangqiang Cui, Jing Yu, Jing Li, Cheng Zeng, Fan Bu, Xiaohong Liao, Hongzhi Hu, Zihui Liang, Chao Chen, Changhai Yi. (2024) Efficient Recycling of Glucose from Cellulose in Textiles Waste by Solid Catalysts. BIOMACROMOLECULES, 26 (1): (591-600). |
| 20. Rongfang Guo, Shuying Zhang, Anyao Li, Ping Zhang, Xin Peng, Xiaoyan Lu, Xiaohui Fan. (2025) Ginsenoside Rb1 and berberine synergistically protect against type 2 diabetes mellitus via GDF15/HAMP pathway throughout the liver lobules: Insights from spatial transcriptomics analysis. PHARMACOLOGICAL RESEARCH, 215 (107711). |
| 21. Youhua Xiao, Xiaodong Lu, Yihang Ma, Zheqi Chen, Xingyu Shang, Ruifeng Hu, Jingwen Ni, Jinfeng Dai, Lina Liu, Jie Mao, Shengxiang Yang, Yingwu Luo. (2024) Highly anisotropic and stretchable birefringent elastomers for multicolored strain displays. CHEMICAL ENGINEERING JOURNAL, 493 (152466). |
| 22. Lingyun Zhang, Xuelei Deng, Jia Xiao, Wei Zhao, Pan Zou, Ruizhe Liao, Keying Xie, Hongdong Liao. (2025) Root metabolites regulated by FERONIA promote phosphorus-solubilizing rhizobacteria enrichment induced by Arabidopsis thaliana coping with phosphorus deficiency. MICROBIOLOGICAL RESEARCH, 292 (128030). |
| 23. Si-wei Rao, Feng-xiang Zhang, Yuan-yuan Duan, Zi-hao Chen, Dong Liang, Wei Shi. (2024) Urea-based deep eutectic solvents enzyme system for high efficiency extraction of alkaloids and flavonoids in plants: Zanthoxylum nitidum (Roxb.) DC. as a case. MICROCHEMICAL JOURNAL, 199 (109964). |
| 24. Yunyun Wang, Wangdi Song, Shengnan Xue, Yue Sheng, Bo Gao, Yanyan Dang, Yan Zhang, Genlin Zhang. (2024) β-Cyclodextrin/dialdehyde glucan-coated keratin nanoparticles for oral delivery of insulin. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, (133805). |
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