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8-Bromo-GTP (aqueous solution) - ≥95%, high purity , CAS No.23197-98-0

    Grade & Purity:
  • ≥95%
In stock
Item Number
B276307
Grouped product items
SKU Size
Availability
Price Qty
B276307-50μl
50μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$403.90

GTP analog. RNA triphosphatase and GTP-hydrolase inhibitor.

View related series
Bacterial (3013)

Basic Description

Synonyms 8-Bromo-GTP | Guanosine 5'-(tetrahydrogen triphosphate), 8-bromo- | [[(2R,3S,4R,5R)-5-(2-amino-1-bromo-6-oxopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate | DTXSID10177777 | 8-Bromoguanosine triphosphate
Specifications & Purity ≥95%
Biochemical and Physiological Mechanisms GTP analog. RNA triphosphatase and GTP-hydrolase inhibitor. Competitive FtsZ polymerization and GTPase inhibitor (IC 50 = 32 μM). Competes with ATP but not UTP for the binding center of RNA-polymerase.
Storage Temp Store at -20°C,Desiccated
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Note Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Store at -20°C (desiccating conditions).

Names and Identifiers

IUPAC Name [[(2R,3S,4R,5R)-5-(2-amino-1-bromo-6-oxopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
INCHI InChI=1S/C10H15BrN5O14P3/c11-16-8(19)4-7(14-10(16)12)15(2-13-4)9-6(18)5(17)3(28-9)1-27-32(23,24)30-33(25,26)29-31(20,21)22/h2-3,5-6,9,17-18H,1H2,(H2,12,14)(H,23,24)(H,25,26)(H2,20,21,22)/t3-,5-,6-,9-/m1/s1
InChIKey LFZGZIRXCAZYFU-UUOKFMHZSA-N
Smiles C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N=C(N(C2=O)Br)N
Isomeric SMILES C1=NC2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N=C(N(C2=O)Br)N
PubChem CID 3082215
Molecular Weight 602.08

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Solubility Supplied in water (10 mM)

Solution Calculators

Reviews

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