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| SKU | Size | Availability |
Price | Qty |
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B276307-50μl
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50μl |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$403.90
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GTP analog. RNA triphosphatase and GTP-hydrolase inhibitor.
| Synonyms | 8-Bromo-GTP | Guanosine 5'-(tetrahydrogen triphosphate), 8-bromo- | [[(2R,3S,4R,5R)-5-(2-amino-1-bromo-6-oxopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate | DTXSID10177777 | 8-Bromoguanosine triphosphate |
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| Specifications & Purity | ≥95% |
| Biochemical and Physiological Mechanisms | GTP analog. RNA triphosphatase and GTP-hydrolase inhibitor. Competitive FtsZ polymerization and GTPase inhibitor (IC 50 = 32 μM). Competes with ATP but not UTP for the binding center of RNA-polymerase. |
| Storage Temp | Store at -20°C,Desiccated |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Note | Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
| Product Description |
Store at -20°C (desiccating conditions). |
| IUPAC Name | [[(2R,3S,4R,5R)-5-(2-amino-1-bromo-6-oxopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate |
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| INCHI | InChI=1S/C10H15BrN5O14P3/c11-16-8(19)4-7(14-10(16)12)15(2-13-4)9-6(18)5(17)3(28-9)1-27-32(23,24)30-33(25,26)29-31(20,21)22/h2-3,5-6,9,17-18H,1H2,(H2,12,14)(H,23,24)(H,25,26)(H2,20,21,22)/t3-,5-,6-,9-/m1/s1 |
| InChIKey | LFZGZIRXCAZYFU-UUOKFMHZSA-N |
| Smiles | C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N=C(N(C2=O)Br)N |
| Isomeric SMILES | C1=NC2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N=C(N(C2=O)Br)N |
| PubChem CID | 3082215 |
| Molecular Weight | 602.08 |
| Solubility | Supplied in water (10 mM) |
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