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7-Hydroxycoumarin glucuronide sodium salt - 98%, high purity , CAS No.168286-98-4

    Grade & Purity:
  • ≥98%
In stock
Item Number
H338882
Grouped product items
SKU Size
Availability
Price Qty
H338882-1mg
1mg
3
$165.90
H338882-5mg
5mg
1
$799.90
H338882-10mg
10mg
2
$1,149.90

a 7-hydroxycoumarin phase II metabolite that can be used as a standard for the analysis of 7-hydroxy coumari

View related series
Metabolite (5307)

Basic Description

Synonyms 7-Hydroxycoumarin glucuronide sodium salt | 7-Hydroxy coumarin glucuronide (sodium salt) | A-D-Glucuronide Sodium Salt | MFCD00674902 | 7-Hydroxy Coumarin beta-D-Glucuronide Sodium Salt | 7-Hydroxycoumarin glucuronide sodium salt is known as a 7-hydroxy c
Specifications & Purity ≥98%
Storage Temp Store at 2-8°C,Argon charged
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

7-Hydroxycoumarin glucuronide sodium salt is a labelled metabolite of Coumarin and 7-hydroxycoumarin phase II. 7-Hydroxycoumarin glucuronide sodium salt can be used as a standard for the analysis of 7-hydroxy coumarin metabolism. 7-Hydroxycoumarin glucuronide sodium salt was one of the eventually formed metabolites following a 1 hour incubation experiment with individual probe substrates, such as Chlorzoxazone and 7-hydroxycoumarin. The measured concentration of formed 7-Hydroxycoumarin glucuronide sodium salt can be indicative of the presence of UGT enzyme after exposure of HepaRG to the original probe substrate. 7-Hydroxycoumarin glucuronide sodium salt was undetectable in an LC-MS/MS analysis test in AR-CALUX.

Application:

7-Hydroxycoumarin glucuronide sodium salt can be used as a standard for the analysis of 7-hydroxycoumarin metabolites;Phase II (UDP-GT) metabolite of 7-hydroxycoumarin;Useful as a pharmacokinetic standard in metabolic studies.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Phenylpropanoids and polyketides
Class Coumarins and derivatives
Subclass Coumarin glycosides
Intermediate Tree Nodes Not available
Direct Parent Coumarin glycosides
Alternative Parents Phenolic glycosides  O-glucuronides  O-glycosyl compounds  1-benzopyrans  Pyranones and derivatives  Beta hydroxy acids and derivatives  Benzenoids  Oxanes  Monosaccharides  Heteroaromatic compounds  Secondary alcohols  Carboxylic acid salts  Lactones  Polyols  Carboxylic acids  Acetals  Oxacyclic compounds  Monocarboxylic acids and derivatives  Hydrocarbon derivatives  Organic sodium salts  Carbonyl compounds  Organic oxides  Organic cations  
Molecular Framework Aromatic heteropolycyclic compounds
Substituents Coumarin-7-o-glycoside - Coumarin o-glycoside - Phenolic glycoside - 1-o-glucuronide - O-glucuronide - Glucuronic acid or derivatives - Glycosyl compound - O-glycosyl compound - Benzopyran - 1-benzopyran - Beta-hydroxy acid - Pyranone - Benzenoid - Pyran - Hydroxy acid - Oxane - Monosaccharide - Heteroaromatic compound - Carboxylic acid salt - Secondary alcohol - Lactone - Organic alkali metal salt - Organoheterocyclic compound - Carboxylic acid derivative - Carboxylic acid - Acetal - Polyol - Monocarboxylic acid or derivatives - Oxacycle - Organic oxygen compound - Organic sodium salt - Organic oxide - Hydrocarbon derivative - Organic salt - Carbonyl group - Organooxygen compound - Alcohol - Organic cation - Aromatic heteropolycyclic compound
Description This compound belongs to the class of organic compounds known as coumarin glycosides. These are aromatic compounds containing a carbohydrate moiety glycosidically bound to a coumarin moiety.
External Descriptors Not available

Names and Identifiers

Pubchem Sid 504769604
Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504769604
IUPAC Name sodium;(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(2-oxochromen-7-yl)oxyoxane-2-carboxylate
INCHI InChI=1S/C15H14O9.Na/c16-9-4-2-6-1-3-7(5-8(6)23-9)22-15-12(19)10(17)11(18)13(24-15)14(20)21;/h1-5,10-13,15,17-19H,(H,20,21);/q;+1/p-1/t10-,11-,12+,13-,15+;/m0./s1
InChIKey SKHLGBDGEPDEME-KSOKONAESA-M
Smiles C1=CC(=CC2=C1C=CC(=O)O2)OC3C(C(C(C(O3)C(=O)[O-])O)O)O.[Na+]
Isomeric SMILES C1=CC(=CC2=C1C=CC(=O)O2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)C(=O)[O-])O)O)O.[Na+]
WGK Germany 3
PubChem CID 23675380
Molecular Weight 360.25

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot Number Certificate Type Date Item
K2324260 Certificate of Analysis Nov 16, 2023 H338882
K2324261 Certificate of Analysis Nov 16, 2023 H338882
K2324262 Certificate of Analysis Nov 16, 2023 H338882
K2324263 Certificate of Analysis Nov 16, 2023 H338882

Chemical and Physical Properties

Solubility DMSO, Water (Slightly, Heated, Sonicated)
Sensitivity Moisture Sensitive
Molecular Weight 360.250 g/mol
XLogP3
Hydrogen Bond Donor Count 3
Hydrogen Bond Acceptor Count 9
Rotatable Bond Count 3
Exact Mass 360.046 Da
Monoisotopic Mass 360.046 Da
Topological Polar Surface Area 146.000 Ų
Heavy Atom Count 25
Formal Charge 0
Complexity 539.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 5
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 2

Solution Calculators

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