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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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H338882-1mg
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1mg |
3
|
$165.90
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|
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H338882-5mg
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5mg |
1
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$799.90
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|
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H338882-10mg
|
10mg |
2
|
$1,149.90
|
|
a 7-hydroxycoumarin phase II metabolite that can be used as a standard for the analysis of 7-hydroxy coumari
| Synonyms | 7-Hydroxycoumarin glucuronide sodium salt | 7-Hydroxy coumarin glucuronide (sodium salt) | A-D-Glucuronide Sodium Salt | MFCD00674902 | 7-Hydroxy Coumarin beta-D-Glucuronide Sodium Salt | 7-Hydroxycoumarin glucuronide sodium salt is known as a 7-hydroxy c |
|---|---|
| Specifications & Purity | ≥98% |
| Storage Temp | Store at 2-8°C,Argon charged |
| Shipped In |
Wet ice This product requires cold chain shipping. Ground and other economy services are not available. |
| Product Description |
7-Hydroxycoumarin glucuronide sodium salt is a labelled metabolite of Coumarin and 7-hydroxycoumarin phase II. 7-Hydroxycoumarin glucuronide sodium salt can be used as a standard for the analysis of 7-hydroxy coumarin metabolism. 7-Hydroxycoumarin glucuronide sodium salt was one of the eventually formed metabolites following a 1 hour incubation experiment with individual probe substrates, such as Chlorzoxazone and 7-hydroxycoumarin. The measured concentration of formed 7-Hydroxycoumarin glucuronide sodium salt can be indicative of the presence of UGT enzyme after exposure of HepaRG to the original probe substrate. 7-Hydroxycoumarin glucuronide sodium salt was undetectable in an LC-MS/MS analysis test in AR-CALUX. Application: 7-Hydroxycoumarin glucuronide sodium salt can be used as a standard for the analysis of 7-hydroxycoumarin metabolites;Phase II (UDP-GT) metabolite of 7-hydroxycoumarin;Useful as a pharmacokinetic standard in metabolic studies. |
Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Phenylpropanoids and polyketides |
| Class | Coumarins and derivatives |
| Subclass | Coumarin glycosides |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Coumarin glycosides |
| Alternative Parents | Phenolic glycosides O-glucuronides O-glycosyl compounds 1-benzopyrans Pyranones and derivatives Beta hydroxy acids and derivatives Benzenoids Oxanes Monosaccharides Heteroaromatic compounds Secondary alcohols Carboxylic acid salts Lactones Polyols Carboxylic acids Acetals Oxacyclic compounds Monocarboxylic acids and derivatives Hydrocarbon derivatives Organic sodium salts Carbonyl compounds Organic oxides Organic cations |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Coumarin-7-o-glycoside - Coumarin o-glycoside - Phenolic glycoside - 1-o-glucuronide - O-glucuronide - Glucuronic acid or derivatives - Glycosyl compound - O-glycosyl compound - Benzopyran - 1-benzopyran - Beta-hydroxy acid - Pyranone - Benzenoid - Pyran - Hydroxy acid - Oxane - Monosaccharide - Heteroaromatic compound - Carboxylic acid salt - Secondary alcohol - Lactone - Organic alkali metal salt - Organoheterocyclic compound - Carboxylic acid derivative - Carboxylic acid - Acetal - Polyol - Monocarboxylic acid or derivatives - Oxacycle - Organic oxygen compound - Organic sodium salt - Organic oxide - Hydrocarbon derivative - Organic salt - Carbonyl group - Organooxygen compound - Alcohol - Organic cation - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as coumarin glycosides. These are aromatic compounds containing a carbohydrate moiety glycosidically bound to a coumarin moiety. |
| External Descriptors | Not available |
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| Pubchem Sid | 504769604 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504769604 |
| IUPAC Name | sodium;(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(2-oxochromen-7-yl)oxyoxane-2-carboxylate |
| INCHI | InChI=1S/C15H14O9.Na/c16-9-4-2-6-1-3-7(5-8(6)23-9)22-15-12(19)10(17)11(18)13(24-15)14(20)21;/h1-5,10-13,15,17-19H,(H,20,21);/q;+1/p-1/t10-,11-,12+,13-,15+;/m0./s1 |
| InChIKey | SKHLGBDGEPDEME-KSOKONAESA-M |
| Smiles | C1=CC(=CC2=C1C=CC(=O)O2)OC3C(C(C(C(O3)C(=O)[O-])O)O)O.[Na+] |
| Isomeric SMILES | C1=CC(=CC2=C1C=CC(=O)O2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)C(=O)[O-])O)O)O.[Na+] |
| WGK Germany | 3 |
| PubChem CID | 23675380 |
| Molecular Weight | 360.25 |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Nov 16, 2023 | H338882 | |
| Certificate of Analysis | Nov 16, 2023 | H338882 | |
| Certificate of Analysis | Nov 16, 2023 | H338882 | |
| Certificate of Analysis | Nov 16, 2023 | H338882 |
| Solubility | DMSO, Water (Slightly, Heated, Sonicated) |
|---|---|
| Sensitivity | Moisture Sensitive |
| Molecular Weight | 360.250 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 9 |
| Rotatable Bond Count | 3 |
| Exact Mass | 360.046 Da |
| Monoisotopic Mass | 360.046 Da |
| Topological Polar Surface Area | 146.000 Ų |
| Heavy Atom Count | 25 |
| Formal Charge | 0 |
| Complexity | 539.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 5 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 2 |