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7-Ethylcamptothecin - ≥96.0%(HPLC), high purity , CAS No.78287-27-1

COA

Grade & Purity:

≥96%(HPLC)

Cas Number: 78287-27-1
Molecular Weight: 376.41
MDL number: MFCD06657922
PubChem CID: 127584
PubChem SID: 488187797

In stock

Item Number

E134852

Grouped product items
SKU	Size	Availability	Price
E134852-50mg	50mg	2	$13.90
E134852-250mg	250mg	3	$51.90
E134852-1g	1g	3	$159.90
E134852-5g	5g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$718.90
E134852-25g	25g	3	$3,231.90

View related series

quinolines (133)

Basic Description

Synonyms	3,3,5-Trimethylcyclohexyl hydroxy(phenyl)acetate \| 7-ETHYLCAMPTOTHECIN [USP IMPURITY] \| Proeptatriene [Italian] \| 4,11-diethyl-4,9-dihydroxy-(4S)-3,4,12,14-tetrahydro-1H-pyrano[3'',4'':6,7]indolizino[1,2-b]quinoline-3,14-dione \| E0781 \| 7-Ethyl-20(S)-camp
Specifications & Purity	≥96%(HPLC)
Shipped In	Normal

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Alkaloids and derivatives
  - Class Camptothecins

Kingdom	Organic compounds
Superclass	Alkaloids and derivatives
Class	Camptothecins
Subclass	Not available
Intermediate Tree Nodes	Not available
Direct Parent	Camptothecins
Alternative Parents	Quinolines and derivatives Pyranopyridines Pyridinones Benzenoids Tertiary alcohols Heteroaromatic compounds Carboxylic acid esters Lactams Lactones Azacyclic compounds Oxacyclic compounds Monocarboxylic acids and derivatives Organonitrogen compounds Organopnictogen compounds Hydrocarbon derivatives Organic oxides Carbonyl compounds
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Camptothecin - Pyranopyridine - Quinoline - Pyridinone - Pyridine - Benzenoid - Heteroaromatic compound - Tertiary alcohol - Carboxylic acid ester - Lactam - Lactone - Monocarboxylic acid or derivatives - Carboxylic acid derivative - Oxacycle - Azacycle - Organoheterocyclic compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Alcohol - Carbonyl group - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as camptothecins. These are heterocyclic compounds comprising a planar pentacyclic ring structure, that includes a pyrrolo[3,4-beta]-quinoline moiety (rings A, B and C), conjugated pyridone moiety (ring D) and one chiral center at position 20 within the alpha-hydroxy lactone ring with (S) configuration (the E-ring).
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

Pubchem Sid	488187797
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488187797
IUPAC Name	(19S)-10,19-diethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
INCHI	InChI=1S/C22H20N2O4/c1-3-12-13-7-5-6-8-17(13)23-19-14(12)10-24-18(19)9-16-15(20(24)25)11-28-21(26)22(16,27)4-2/h5-9,27H,3-4,10-11H2,1-2H3/t22-/m0/s1
InChIKey	MYQKIWCVEPUPIL-QFIPXVFZSA-N
Smiles	CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)C4(CC)O)C2=NC5=CC=CC=C51
Isomeric SMILES	CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)O)C2=NC5=CC=CC=C51
Molecular Weight	376.41
Reaxy-Rn	11567758
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=11567758&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

7 results found

Lot Number	Certificate Type	Date	Item
G2308117	Certificate of Analysis	Apr 09, 2025	E134852
G2308111	Certificate of Analysis	Apr 09, 2025	E134852
F2207190	Certificate of Analysis	Mar 14, 2024	E134852
F2207191	Certificate of Analysis	Mar 14, 2024	E134852
F2207193	Certificate of Analysis	Mar 14, 2024	E134852
F2207198	Certificate of Analysis	Mar 14, 2024	E134852
E1703004	Certificate of Analysis	Dec 07, 2022	E134852

Chemical and Physical Properties

Specific Rotation[α]	43° (C=0.4,CHCl3:MeOH=8:2)
Molecular Weight	376.400 g/mol
XLogP3	1.800
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	2
Exact Mass	376.142 Da
Monoisotopic Mass	376.142 Da
Topological Polar Surface Area	79.700 Å²
Heavy Atom Count	28
Formal Charge	0
Complexity	787.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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