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7-Amino-4-trifluoromethylcoumarin - 10mM in DMSO, high purity , CAS No.53518-15-3
Fluorescent marker. Substrate for fluorogenic enzyme assays.
Basic Description
Synonyms
7-amino-4-(trifluoromethyl)-1-benzopyran-2-one | 7-Amino-4-(trifluoromethyl)-2-benzopyrone | BDBM83209 | HY-D0981 | A15632 | CCG-245871 | Coumarin 490 | SMR000034073 | 7-Amino-4-(trifluoromethyl)coumarin | 7-amino-4-trifluoromethylcumarin | 7-Amino-4-trif
Specifications & Purity
10mM in DMSO
Biochemical and Physiological Mechanisms
Fluorescent marker. Substrate for fluorogenic enzyme assays. Calibration standard.
Storage Temp
Store at -80°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description
Product Application:
7-Amino-4-(trifluoromethyl)coumarin is used in the synthesis of substrates for the fluorometric assay of proteolytic enzymes in biological fluids. It is suitable as laser dye.
Taxonomic Classification
Kingdom
Organic compounds
Superclass
Phenylpropanoids and polyketides
Class
Coumarins and derivatives
Subclass
Not available
Intermediate Tree Nodes
Not available
Direct Parent
Coumarins and derivatives
Alternative Parents
1-benzopyrans Pyranones and derivatives Benzenoids Heteroaromatic compounds Lactones Oxacyclic compounds Primary amines Organopnictogen compounds Organooxygen compounds Organofluorides Organic oxides Hydrocarbon derivatives Alkyl fluorides
Molecular Framework
Aromatic heteropolycyclic compounds
Substituents
Coumarin - Benzopyran - 1-benzopyran - Pyranone - Pyran - Benzenoid - Heteroaromatic compound - Lactone - Organoheterocyclic compound - Oxacycle - Alkyl fluoride - Organic oxide - Organopnictogen compound - Primary amine - Organooxygen compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Hydrocarbon derivative - Organic oxygen compound - Organic nitrogen compound - Amine - Alkyl halide - Aromatic heteropolycyclic compound
Description
This compound belongs to the class of organic compounds known as coumarins and derivatives. These are polycyclic aromatic compounds containing a 1-benzopyran moiety with a ketone group at the C2 carbon atom (1-benzopyran-2-one).
External Descriptors
7-aminocoumarins
Data sources
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Associated Targets(Human)
Associated Targets(non-human)
Mechanisms of Action
Mechanism of Action
Action Type
target ID
Target Name
Target Type
Target Organism
Binding Site Name
References
Names and Identifiers
IUPAC Name
7-amino-4-(trifluoromethyl)chromen-2-one
INCHI
InChI=1S/C10H6F3NO2/c11-10(12,13)7-4-9(15)16-8-3-5(14)1-2-6(7)8/h1-4H,14H2
InChIKey
JBNOVHJXQSHGRL-UHFFFAOYSA-N
Smiles
C1=CC2=C(C=C1N)OC(=O)C=C2C(F)(F)F
Isomeric SMILES
C1=CC2=C(C=C1N)OC(=O)C=C2C(F)(F)F
WGK Germany
3
Molecular Weight
229.16
Beilstein
4456797
Reaxy-Rn
4456797
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4456797&ln=
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
Chemical and Physical Properties
Melt Point(°C)
222-223°C
Molecular Weight
229.150 g/mol
XLogP3
2.100
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Rotatable Bond Count
0
Exact Mass
229.035 Da
Monoisotopic Mass
229.035 Da
Topological Polar Surface Area
52.300 Ų
Heavy Atom Count
16
Formal Charge
0
Complexity
337.000
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
The total count of all stereochemical bonds
0
Covalently-Bonded Unit Count
1
Citations of This Product
1.
Yi Sun, Wei Zhang, Shan Lu, Wenhua Miao, Meiling Chen, Fei Liu, Haining Na, Jin Zhu.
(2023)
Cellulose-based fluorescent materials fabricated in CO2 switchable solvent for freshness monitoring. CARBOHYDRATE POLYMERS,
301
(120346).
2.
Zirui Zheng, Ziyun Yang, Zehua Meng, Siyang Liu, Tianyue Wu, Chengyi He, Chenhui Zhang, Ma Chen, Yuxia Gao, Fengpei Du.
(2024)
Sustainable nanocarriers fabricated by the dipeptide-based co-assemblies for enhancing the delivery and translocation of herbicide. Environmental Science-Nano,
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2 Citations