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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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H754215-25mg
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25mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$79.90
|
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|
H754215-50mg
|
50mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$95.90
|
|
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H754215-100mg
|
100mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$159.90
|
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| Synonyms | 2,4,5-Trihydroxyphenethylamine hydrochloride | 2,5-Dihydroxytyramine hydrochloride | 2-(2,4,5-Trihydroxyphenyl)ethylamine hydrochloride | 6-OHDA |
|---|---|
| Specifications & Purity | ≥95% |
| Biochemical and Physiological Mechanisms | Neurotoxin that destroys catecholaminergic terminals. |
| Storage Temp | Store at 2-8°C,Protected from light,Argon charged |
| Shipped In |
Wet ice This product requires cold chain shipping. Ground and other economy services are not available. |
| Product Description |
6-Hydroxydopamine hydrochloride is a selective catecholaminergic neurotoxin. 6-Hydroxydopamine hydrochloride depletes brain catecholamine levels via uptake and accumulation by a transport mechanism specific to these neurons. Causes almost complete destruction of nigral dopaminergic neurons and their striatal terminals when injected into the substantia nigra of rats, producing an animal model of Parkinson's disease. |
Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Phenols |
| Subclass | Benzenediols |
| Intermediate Tree Nodes | Catechols |
| Direct Parent | Catecholamines and derivatives |
| Alternative Parents | Phenethylamines Hydroxyquinols and derivatives 2-arylethylamines Aralkylamines 1-hydroxy-2-unsubstituted benzenoids Polyols Organopnictogen compounds Monoalkylamines Hydrochlorides Hydrocarbon derivatives |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Catecholamine - Hydroxyquinol derivative - Phenethylamine - 2-arylethylamine - 1-hydroxy-2-unsubstituted benzenoid - Aralkylamine - Monocyclic benzene moiety - Polyol - Primary amine - Amine - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Hydrochloride - Aromatic homomonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as catecholamines and derivatives. These are compounds containing 4-(2-Aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] or a derivative thereof formed by substitution. |
| External Descriptors | Not available |
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| IUPAC Name | 5-(2-aminoethyl)benzene-1,2,4-triol;hydrochloride |
|---|---|
| INCHI | InChI=1S/C8H11NO3.ClH/c9-2-1-5-3-7(11)8(12)4-6(5)10;/h3-4,10-12H,1-2,9H2;1H |
| InChIKey | QLMRJHFAGVFUAC-UHFFFAOYSA-N |
| Smiles | C1=C(C(=CC(=C1O)O)O)CCN.Cl |
| Isomeric SMILES | C1=C(C(=CC(=C1O)O)O)CCN.Cl |
| WGK Germany | 3 |
| RTECS | DC4650000 |
| Molecular Weight | 205.64 |
| Beilstein | 4274007 |
| Reaxy-Rn | 4274007 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4274007&ln= |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Jun 18, 2025 | H754215 | |
| Certificate of Analysis | Jun 18, 2025 | H754215 | |
| Certificate of Analysis | Jun 18, 2025 | H754215 | |
| Certificate of Analysis | Jun 18, 2025 | H754215 | |
| Certificate of Analysis | Jun 18, 2025 | H754215 | |
| Certificate of Analysis | Jun 18, 2025 | H754215 |
| Solubility | Soluble in water (>50 mg/ml). |
|---|---|
| Sensitivity | Hygroscopic;Light sensitive |
| Melt Point(°C) | 232-233 °C |
| Molecular Weight | 205.640 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 5 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 2 |
| Exact Mass | 205.051 Da |
| Monoisotopic Mass | 205.051 Da |
| Topological Polar Surface Area | 86.700 Ų |
| Heavy Atom Count | 13 |
| Formal Charge | 0 |
| Complexity | 142.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 2 |