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6-Dodecanoyl-N,N-dimethyl-2-naphthylamine - ≥97.0% (HPLC),for fluorescenceAnalysis, high purity , CAS No.74515-25-6
Basic Description
Synonyms
Laurdan | Y97FBL93VW | N,N-Dimethyl-6-dodecanoyl-2-naphthylamine | AS-78851 | FT-0621105 | Laurdan | MFCD00467560 | 1-(6-(Dimethylamino)-2-naphthalenyl)-1-dodecanone | Q15426238 | 2-[(5S)-2,4-DIOXOTHIAZOLIDIN-5-YL]ACETATE | DTXSID80225517 | HY-D0080 | 1-D
Specifications & Purity
for fluorescence analysis, ≥97%(HPLC)
Biochemical and Physiological Mechanisms
6-Dodecanoyl-N,N-dimethyl-2-naphthylamine is a fluorescent membrane probe used in phospholipid multilamellar aggregates which distinguishes between phase transitions, phase fluctuations and the coexistence of phase domains. Studies indicate that the bulky
Storage Temp
Protected from light,Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
for fluorescence analysis
Product Description
fluorescence λex 366 nm; λem 497 nm in methanol
Taxonomic Classification
Kingdom
Organic compounds
Superclass
Benzenoids
Class
Benzene and substituted derivatives
Subclass
Butyrophenones
Intermediate Tree Nodes
Not available
Direct Parent
Butyrophenones
Alternative Parents
Naphthalenes Dialkylarylamines Aryl alkyl ketones Organopnictogen compounds Organic oxides Hydrocarbon derivatives
Molecular Framework
Aromatic homopolycyclic compounds
Substituents
Butyrophenone - Naphthalene - Tertiary aliphatic/aromatic amine - Aryl ketone - Aryl alkyl ketone - Dialkylarylamine - Ketone - Tertiary amine - Organopnictogen compound - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Amine - Organic nitrogen compound - Organic oxide - Hydrocarbon derivative - Aromatic homopolycyclic compound
Description
This compound belongs to the class of organic compounds known as butyrophenones. These are compounds containing 1-phenylbutan-1-one moiety.
External Descriptors
Not available
Data sources
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Names and Identifiers
Pubchem Sid
504756594
Pubchem Sid Url
https://pubchem.ncbi.nlm.nih.gov/substance/504756594
IUPAC Name
1-[6-(dimethylamino)naphthalen-2-yl]dodecan-1-one
INCHI
InChI=1S/C24H35NO/c1-4-5-6-7-8-9-10-11-12-13-24(26)22-15-14-21-19-23(25(2)3)17-16-20(21)18-22/h14-19H,4-13H2,1-3H3
InChIKey
JHDGGIDITFLRJY-UHFFFAOYSA-N
Smiles
CCCCCCCCCCCC(=O)C1=CC2=C(C=C1)C=C(C=C2)N(C)C
Isomeric SMILES
CCCCCCCCCCCC(=O)C1=CC2=C(C=C1)C=C(C=C2)N(C)C
Molecular Weight
353.54
Reaxy-Rn
7379104
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=7379104&ln=
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
Chemical and Physical Properties
Solubility
Solubility: Soluble in DMF, Acetonitrile, and Methanol
Sensitivity
Light sensitive.
Molecular Weight
353.500 g/mol
XLogP3
8.100
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
12
Exact Mass
353.272 Da
Monoisotopic Mass
353.272 Da
Topological Polar Surface Area
20.300 Ų
Heavy Atom Count
26
Formal Charge
0
Complexity
392.000
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
The total count of all stereochemical bonds
0
Covalently-Bonded Unit Count
1
Citations of This Product
1.
Yang Xiaoling, Zhao Shunan, Deng Yong, Xu Weidong, Wang Zonghan, Wang Wenjun, Lv Ruiling, Liu Donghong.
(2023)
Antibacterial activity and mechanisms of α-terpineol against foodborne pathogenic bacteria. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,
(1-13).
2.
Hua-Hua Liu, Yang Xu, Cao-Jie Li, Shu-Jung Hsu, Xia-Hui Lin, Rui Zhang, Jie Chen, Jun Chen, Dong-Mei Gao, Jie-Feng Cui, Xin-Rong Yang, Zheng-Gang Ren, Rong-Xin Chen.
(2022)
An SCD1-dependent mechanoresponsive pathway promotes HCC invasion and metastasis through lipid metabolic reprogramming. MOLECULAR THERAPY,
30
(2554-2567).
3.
Chen Yingxian, Zhao Qian, Han Junhua, Lan Xinmiao, Che Jing, Chen Meiwan, Liang Xing-Jie, Ma Xiaowei.
(2022)
Dual Drug Loaded pH-sensitive Micelles for Efficient Bacterial Infection Treatment. PHARMACEUTICAL RESEARCH,
39
(6):
(1165-1180).
4.
Meng Zhao, Fangning Qu, Zhengjun Wu, Katsuyoshi Nishinari, Glyn O. Phillips, Yapeng Fang.
(2017)
Protection mechanism of alginate microcapsules with different mechanical strength for Lactobacillus plantarum ST-III. FOOD HYDROCOLLOIDS,
66
(396).
5.
Menghua Gao, Jiafeng Zhong, Xinxin Liu, Yanjun Zhao, Dingcheng Zhu, Xiaohuo Shi, Xuehan Xu, Qin Zhou, Wenjing Xuan, Yue Zhang, Yaofeng Zhou, Jianjun Cheng.
(2025)
Deciphering the Role of PEGylation on the Lipid Nanoparticle-Mediated mRNA Delivery to the Liver. ACS Nano,
6.
Xiaoyi Cheng, Ruiqi Peng, Mingxi Zou, Yan Chen, Wenkang Li, Zhongjiang Wang, Jing Xu, Zengwang Guo.
(2025)
Effect of phase transition of soy protein-chitosan complexes on liposomes stability: The perspective of membrane structure and inlaid stabilization mechanism. FOOD CHEMISTRY,
480
(143911).
7.
Yongjie Zhu, Wanying Xu, Wenwen Chen, Bowen Li, Guoyu Li, Haoran Deng, Licong Zhang, Changxuan Shao, Anshan Shan.
(2025)
Self-assembling peptide with dual function of cell penetration and antibacterial as a nano weapon to combat intracellular bacteria. Science Advances,
11
(6):
(2025 Feb;11(6)).
8.
Ye Zifan, Fu Lei, Li Shuangyu, Chen Ziying, Ouyang Jianhong, Shang Xinci, Liu Yanli, Gao Lianghui, Wang Yipeng.
(2024)
Synergistic collaboration between AMPs and non-direct antimicrobial cationic peptides. Nature Communications,
15
(1):
(1-26).
9.
Qianwei Qu, Xingyu Huang, Zhenxin Zhu, Jun Wang, Mengmeng Zhao, Wenqiang Cui, Yadan Zheng, Yanyan Liu, Xueying Chen, Zhiyun Zhang, Na Dong, Chunliu Dong, Yanhua Li.
(2025)
Targeting membrane integrity and imidazoleglycerol-phosphate dehydratase: Sanguinarine multifaceted approach against Staphylococcus aureus biofilms. PHYTOMEDICINE,
138
(156428).
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9 Citations
J2326686