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5-Methyluridine - 10mM in DMSO, high purity , CAS No.1463-10-1

    Grade & Purity:
  • 10mM in DMSO
In stock
Item Number
M421691
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Availability
Price Qty
M421691-1ml
1ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$159.90

Basic Description

Synonyms 5-Methyluridine | 1463-10-1 | Ribothymidine | Thymine riboside | Ribosylthymine | Uridine, 5-methyl- | ribosylthymidine | beta-D-Ribofuranoside | Thymine ribofuranoside | 1-(beta-D-ribofuranosyl)thymine | CHEBI:45996 | ZS1409014A | 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl
Specifications & Purity 10mM in DMSO
Storage Temp Store at -80°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Nucleosides, nucleotides, and analogues
Class Pyrimidine nucleosides
Subclass Not available
Intermediate Tree Nodes Not available
Direct Parent Pyrimidine nucleosides
Alternative Parents Glycosylamines  Pentoses  Pyrimidones  Hydropyrimidines  Tetrahydrofurans  Heteroaromatic compounds  Vinylogous amides  Ureas  Lactams  Secondary alcohols  Oxacyclic compounds  Azacyclic compounds  Primary alcohols  Organopnictogen compounds  Organonitrogen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular Framework Aromatic heteromonocyclic compounds
Substituents Pyrimidine nucleoside - Glycosyl compound - N-glycosyl compound - Pentose monosaccharide - Pyrimidone - Hydropyrimidine - Monosaccharide - Pyrimidine - Vinylogous amide - Tetrahydrofuran - Heteroaromatic compound - Urea - Secondary alcohol - Lactam - Organoheterocyclic compound - Oxacycle - Azacycle - Hydrocarbon derivative - Organopnictogen compound - Organooxygen compound - Organonitrogen compound - Primary alcohol - Alcohol - Organic oxygen compound - Organic oxide - Organic nitrogen compound - Aromatic heteromonocyclic compound
Description This compound belongs to the class of organic compounds known as pyrimidine nucleosides. These are compounds comprising a pyrimidine base attached to a ribosyl or deoxyribosyl moiety.
External Descriptors methyluridine

Associated Targets(Human)

WI-38 (2654 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HeLa (62764 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Vero (26788 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

IUPAC Name 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
INCHI InChI=1S/C10H14N2O6/c1-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)18-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,9-/m1/s1
InChIKey DWRXFEITVBNRMK-JXOAFFINSA-N
Smiles CC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O
Isomeric SMILES CC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O
WGK Germany 3
Molecular Weight 258.23
Beilstein 24(5)7,172
Reaxy-Rn 24733125
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=24733125&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Specific Rotation[α] -8 ° (C=2, H2O)
Melt Point(°C) 183°C
Molecular Weight 258.230 g/mol
XLogP3 -1.600
Hydrogen Bond Donor Count 4
Hydrogen Bond Acceptor Count 6
Rotatable Bond Count 2
Exact Mass 258.085 Da
Monoisotopic Mass 258.085 Da
Topological Polar Surface Area 119.000 Ų
Heavy Atom Count 18
Formal Charge 0
Complexity 409.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 4
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

1. Chen Yao, Daizhu Lv, Xueqing Zhou, Pengcheng Fu, Wen Sun, Jinlian Chen, Huan Lin.  (2024)  Exploring urinary modified nucleosides as biomarkers for diabetic retinopathy: Development and validation of a ultra performance liquid chromatography-tandem mass spectrometry method.  JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES,  1232  (123968). 
2. Meng Chu, Yichao Qin, Xiuying Lin, Li Ma, Dehai Deng, Daizhu Lv, Pengcheng Fu, Huan Lin.  (2023)  A Preliminary Survey of Transfer RNA Modifications and Modifying Enzymes of the Tropical Plant Cocos nucifera L..  Genes,  14  (6): (1287). 
3. Gefei Huang, Feng Zhang, Dongying Xie, Yiming Ma, Pengxi Wang, Guodong Cao, Leijian Chen, Siyi Lin, Zhongying Zhao, Zongwei Cai.  (2023)  High-throughput profiling of RNA modifications by ultra-performance liquid chromatography coupled to complementary mass spectrometry: Methods, quality control, and applications.  TALANTA,  263  (124697). 
4. Zhiwei Lu, Xinyue Liu, Xuejiao Li, Chuanjia Zhai, Yulian Shi, Xiaoyan Gao.  (2022)  BH+/MH+-matching method for discovery of cis-diol-containing modified nucleosides in urine by ribose-targeted solid phase extraction followed by dual-mass spectrometry platform identification.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,  210  (114555). 
5. Yang Huang, Tingting Zhang, Yumei Zhao, Haibo Zhou, Guangyun Tang, Marianne Fillet, Jacques Crommen, Zhengjin Jiang.  (2017)  Simultaneous analysis of nucleobases, nucleosides and ginsenosides in ginseng extracts using supercritical fluid chromatography coupled with single quadrupole mass spectrometry.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,  144  (213). 
6. Wang Xue-Jie, You Jin-Zong.  (2015)  Study on the molecular structure and thermal stability of pyrimidine nucleoside analogs.  JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY,  120  (1): (1009-1025). 
7. Zhang Lei, Dai Xiaojun, Xu Fei, Wang Fuqiang, Gong Bolin, Wei Yinmao.  (2012)  Preparation of imidazole-functionalized silica by surface-initiated atom transfer radical polymerization and its application for hydrophilic interaction chromatography.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  404  (5): (1477-1484). 
8. Xiang Yuqian, Huang Yu, Yan Xiaohui, Zhu Zhipeng, Wu Dapeng, Gao Peng, Li Jiulong.  (2024)  Retention and Selectivity on Hydrophilic Interaction Liquid Chromatography Columns Modified with Polyethylene Glycol of Different Chain Length.  CHROMATOGRAPHIA,    (1-13). 
9. Deng Dehai, Qin Yichao, Lin Xiuying, Chu Meng, Lv Daizhu, Lin Huan.  (2025)  Unveiling transfer RNA modifications of oil palm and their dynamic changes during fruit ripening.  BMC PLANT BIOLOGY,  25  (1): (1-17). 

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