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5-Amino-2-(4-aminophenyl)benzimidazole - 98%, high purity , CAS No.7621-86-5

13 Citations COA COA
    Grade & Purity:
  • ≥98%
In stock
Item Number
A186464
Grouped product items
SKU Size
Availability
 Price Qty
A186464-1g
1g
4
$38.90
A186464-5g
5g
1
$86.90
A186464-25g
25g
3
$302.90
A186464-100g
100g
2
$847.90
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View related series
Benzimidazoles (91) Five-Membered Heterocyclic Compounds (2064)

Basic Description

Synonyms AS-66542 | BDBM53882 | Oprea1_357955 | A865535 | EINECS 231-538-6 | FT-0699611 | SR-01000389407 | 2-(4-Aminophenyl)-1H-benzimidazol-2-amine | CBDivE_010161 | SCHEMBL159873 | 2-(4-Aminophenyl)-1H- benzimidazol-5-amine (APBIA) | Benzimidazole, 5-amino-2-(p-
Specifications & Purity ≥98%
Storage Temp Room temperature,Argon charged
Shipped In Normal

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organoheterocyclic compounds
Class Benzimidazoles
Subclass Phenylbenzimidazoles
Intermediate Tree Nodes Not available
Direct Parent Phenylbenzimidazoles
Alternative Parents Phenylimidazoles  Aniline and substituted anilines  Heteroaromatic compounds  Azacyclic compounds  Primary amines  Organopnictogen compounds  Hydrocarbon derivatives  
Molecular Framework Aromatic heteropolycyclic compounds
Substituents Phenylbenzimidazole - 2-phenylimidazole - Aniline or substituted anilines - Monocyclic benzene moiety - Benzenoid - Azole - Imidazole - Heteroaromatic compound - Azacycle - Hydrocarbon derivative - Organopnictogen compound - Organonitrogen compound - Organic nitrogen compound - Primary amine - Amine - Aromatic heteropolycyclic compound
Description This compound belongs to the class of organic compounds known as phenylbenzimidazoles. These are compounds containing a phenylbenzimidazole skeleton, which consists of a benzimidazole moiety where its imidazole ring is attached to a phenyl group.
External Descriptors Not available

Associated Targets(Human)

VDR Tclin Vitamin D receptor (26531 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PTH1R Tclin Parathyroid hormone receptor (47172 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GLA Tclin Alpha-galactosidase A (5444 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GAA Tclin Lysosomal alpha-glucosidase (35701 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SMPD1 Tchem Sphingomyelin phosphodiesterase (13561 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HeLa (62764 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
FEN1 Tchem Flap endonuclease 1 (12055 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GNAS Tbio Guanine nucleotide-binding protein G(s), subunit alpha (103405 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
POLK Tbio DNA polymerase kappa (8653 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ERG Tbio Transcriptional regulator ERG (5589 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SMN1 Tchem Survival motor neuron protein (34246 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
RECQL Tbio ATP-dependent DNA helicase Q1 (5575 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
NPC1 Tchem Niemann-Pick C1 protein (18985 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
RAB9A Tbio Ras-related protein Rab-9A (22488 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
RXFP1 Tchem Relaxin receptor 1 (6345 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GFER Tchem FAD-linked sulfhydryl oxidase ALR (1466 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ATAD5 Tbio ATPase family AAA domain-containing protein 5 (122566 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
BAZ2B Tchem Bromodomain adjacent to zinc finger domain protein 2B (56204 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
RAPGEF3 Tchem Rap guanine nucleotide exchange factor 3 (15528 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MEN1 Tchem Menin/Histone-lysine N-methyltransferase MLL (48157 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

M1AAP Zinc aminopeptidase (902 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GCN5 Histone acetyltransferase GCN5 (89 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Luciferin 4-monooxygenase (66902 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mapt Microtubule-associated protein tau (6 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
FTL Ferritin light chain (43324 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CCT2 T-complex protein 1 subunit beta (5007 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

Pubchem Sid 504753176
Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504753176
IUPAC Name 2-(4-aminophenyl)-3H-benzimidazol-5-amine
INCHI InChI=1S/C13H12N4/c14-9-3-1-8(2-4-9)13-16-11-6-5-10(15)7-12(11)17-13/h1-7H,14-15H2,(H,16,17)
InChIKey XAFOTXWPFVZQAZ-UHFFFAOYSA-N
Smiles C1=CC(=CC=C1C2=NC3=C(N2)C=C(C=C3)N)N
Isomeric SMILES C1=CC(=CC=C1C2=NC3=C(N2)C=C(C=C3)N)N
Molecular Weight 224.3
Reaxy-Rn 747472
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=747472&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

17 results found

Lot Number Certificate Type Date Item
D2527034 Certificate of Analysis Mar 14, 2025 A186464
D2527035 Certificate of Analysis Mar 14, 2025 A186464
D2527106 Certificate of Analysis Mar 14, 2025 A186464
E2227357 Certificate of Analysis Mar 04, 2025 A186464
E2227379 Certificate of Analysis Mar 04, 2025 A186464
E2227367 Certificate of Analysis Mar 04, 2025 A186464
K2110578 Certificate of Analysis Aug 21, 2024 A186464
C2425124 Certificate of Analysis Jan 20, 2024 A186464
C2425126 Certificate of Analysis Jan 20, 2024 A186464
C2425122 Certificate of Analysis Jan 20, 2024 A186464
C2425120 Certificate of Analysis Jan 20, 2024 A186464
C2425121 Certificate of Analysis Jan 20, 2024 A186464
C2425123 Certificate of Analysis Jan 20, 2024 A186464
C2425125 Certificate of Analysis Jan 20, 2024 A186464
E2008154 Certificate of Analysis Feb 13, 2023 A186464
E2324234 Certificate of Analysis Mar 18, 2022 A186464
E2324292 Certificate of Analysis Mar 18, 2022 A186464

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Chemical and Physical Properties

Solubility Soluble in methanol
Sensitivity air sensitive
Melt Point(°C) 236 °C
Molecular Weight 224.260 g/mol
XLogP3 1.900
Hydrogen Bond Donor Count 3
Hydrogen Bond Acceptor Count 3
Rotatable Bond Count 1
Exact Mass 224.106 Da
Monoisotopic Mass 224.106 Da
Topological Polar Surface Area 80.700 Ų
Heavy Atom Count 17
Formal Charge 0
Complexity 262.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

How to Cite Aladdin Scientific Products?
1. Xiaofei Wang, Yang He, Xinli Xiao, Wei Zhao, Jinsong Leng.  (2024)  High-Tg shape memory polyimide composites with “spot-plane” directional thermally conduction structure based on AlN nanoparticles and acidified graphene.  COMPOSITE STRUCTURES,  330  (117846). 
2. Haiyan Jiang, Tingting Li, Lu Bai, Jiuli Han, Xiaochun Zhang, Haifeng Dong, Shaojuan Zeng, Shuangjiang Luo, Xiangping Zhang.  (2023)  Polyimide/Ionic Liquids Hybrid Membranes with NH3-Philic Channels for Ammonia-Based CO2 Separation Processes.  ACS Applied Materials & Interfaces,  15  (44): (51204–51214). 
3. Xiaofei Wang, Yang He, Xinli Xiao, Jinsong Leng.  (2023)  Rapid-actuating high-Tg shape memory polyimide composites with synergistic “micro-nano” thermal conduction networks.  COMPOSITES SCIENCE AND TECHNOLOGY,  239  (110052). 
4. Xing Liu, Jianjun Zhou, Jianqing Zhao, Shumei Liu.  (2023)  Design and synthesis of polyetherimides as a flame-retarded thermolatent hardener for high-performance epoxy thermosets.  COMPOSITES PART B-ENGINEERING,  259  (110754). 
5. Xiaofei Wang, Yang He, Jinsong Leng.  (2022)  Shape memory polyimides and composites with tunable chain stiffness and ultrahigh transition temperature range.  COMPOSITES PART A-APPLIED SCIENCE AND MANUFACTURING,  163  (107237). 
6. Huikang Xu, Weijun Chen, Chengyang Wang, Tingting Jia, Dezhi Wang, Gang Li, Daoxiang Zhao, Baojun Cui, Zhen Fan, Xupeng Fan, Haitao Zhang, Tenghai Gan, Hao Xing, Liwei Zhao, Changwei Liu.  (2023)  Ultralight and flexible silver nanoparticle-wrapped “scorpion pectine-like” polyimide hybrid aerogels as sensitive pressor sensors with wide temperature range and consistent conductivity response.  CHEMICAL ENGINEERING JOURNAL,  453  (139647). 
7. Yanlin Liu, Zhen Yu, Guangming Lu, Wanding Chen, Zixian Ye, Yueran He, Zhaobin Tang, Jin Zhu.  (2023)  Versatile levulinic acid-derived dynamic covalent thermosets enabled by in situ generated imine and multiple hydrogen bonds.  CHEMICAL ENGINEERING JOURNAL,  451  (139053). 
8. You Ning, Zhang Chenxi, Liang Yachao, Zhang Qi, Fu Peng, Liu Minying, Zhao Qingxiang, Cui Zhe, Pang Xinchang.  (2019)  Facile Fabrication of Size-Tunable Core/Shell Ferroelectric/Polymeric Nanoparticles with Tailorable Dielectric Properties via Organocatalyzed Atom Transfer Radical Polymerization Driven by Visible Light.  Scientific Reports,  9  (1): (1-12). 
9. Yuxuan Zheng, Weiyi Xu, Yulin Wu, Jingyi Ding, Haowei Yu, Xinze You, Yixing Wang, Zhi Xu.  (2025)  A cross-linked sulfonated polyimide membrane with regulated acid-base interaction and high-performance for vanadium redox flow battery.  JOURNAL OF MEMBRANE SCIENCE,  718  (123651). 
10. Hui-Kang Xu, Chang Dong, Gui-Lin Song, Shui-Juan Peng, Yue-Yi Wang, Ding-Xiang Yan.  (2025)  A Novel Positive Temperature Coefficient Composite with Low Curie Temperatures for Thermal Management.  MACROMOLECULAR RAPID COMMUNICATIONS,    (2401064). 
11. Long Ni, Yinfu Luo, Xiaochuang Di, Xiaoting Liao, Liwei Yan, Mei Liang, Shengtai Zhou, Huawei Zou.  (2024)  Fabrication of multifunctional polyimide foams with co-polymerized benzimidazole moieties for excellent thermal insulation and flame retardancy applications.  POLYMER,  308  (127367). 
12. Xiaofei Wang, Yang He, Xinli Xiao, Yanju Liu, Jinsong Leng.  (2024)  Properties of shape memory polyimide composites with continuous “brick-and-mortar” layered structure: High flame retardancy, ablation resistance, and high mechanical properties.  COMPOSITES PART A-APPLIED SCIENCE AND MANUFACTURING,  181  (108151). 
13. Ronghao Li, Junping Zheng.  (2025)  Triple Effects of Fe3+ for the Integration of Mechanical Robustness, Reprocessability, and Unprecedented Thermal Stability into Polydimethylsiloxane.  MACROMOLECULES,  58  (7): (3460-3470). 

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