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4-Quinolinecarboxylic acid - 98%, high purity , CAS No.486-74-8

COA

Grade & Purity:

≥98%

Cas Number: 486-74-8
Molecular Weight: 173.17
Beilstein Registry Number: 5224
EC Number: 207-640-1
MDL number: MFCD00006782
PubChem CID: 10243
PubChem SID: 488181095

In stock

Item Number

Q123917

Grouped product items
SKU	Size	Availability	Price
Q123917-200mg	200mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$9.90
Q123917-1g	1g	10	$30.90
Q123917-5g	5g	3	$87.90
Q123917-25g	25g	3	$520.90

View related series

Endogenous Metabolite (959) Metabolic Enzyme/Protease (4860) Metabolite (5307) Pyridines (1259) Six-Membered Heterocyclic Compounds (1696)

Basic Description

Synonyms	Q27102986 \| AB01122702-03 \| EINECS 207-640-1 \| s6095 \| 5-22-03-00204 (Beilstein Handbook Reference) \| 4-Quinolinecarboxylic acid \| A7349 \| WLN: T66 BNJ EVQ \| 4-quinoline carboxylic acid \| AC-25671 \| Quinoline-4-carboxylic acid \| quinoline4-carboxylic acid
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	4-Quinolinecarboxylic acid showed anti-tumor activity against L1210 leukemia and B16 melanoma.
Storage Temp	Argon charged
Shipped In	Normal
Product Description	4-Quinolinecarboxylic acid was used in the coupling reaction with diamine linker. A 4-quinolinecarboxylic acid analogue, brequinar sodium was used to inhibit dihydroorotate dehydrogenase and the de novo biosynthesis of pyrimidine.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Quinolines and derivatives
    - Subclass Quinoline carboxylic acids

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Quinolines and derivatives
Subclass	Quinoline carboxylic acids
Intermediate Tree Nodes	Not available
Direct Parent	Quinoline carboxylic acids
Alternative Parents	Pyridinecarboxylic acids Benzenoids Heteroaromatic compounds Monocarboxylic acids and derivatives Carboxylic acids Azacyclic compounds Organopnictogen compounds Organooxygen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Quinoline-4-carboxylic acid - Pyridine carboxylic acid - Pyridine carboxylic acid or derivatives - Benzenoid - Pyridine - Heteroaromatic compound - Carboxylic acid derivative - Carboxylic acid - Monocarboxylic acid or derivatives - Azacycle - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Organooxygen compound - Organonitrogen compound - Organopnictogen compound - Organic oxygen compound - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as quinoline carboxylic acids. These are quinolines in which the quinoline ring system is substituted by a carboxyl group at one or more positions.
External Descriptors	quinolinemonocarboxylic acid
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	488181095
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488181095
IUPAC Name	quinoline-4-carboxylic acid
INCHI	InChI=1S/C10H7NO2/c12-10(13)8-5-6-11-9-4-2-1-3-7(8)9/h1-6H,(H,12,13)
InChIKey	VQMSRUREDGBWKT-UHFFFAOYSA-N
Smiles	C1=CC=C2C(=C1)C(=CC=N2)C(=O)O
Isomeric SMILES	C1=CC=C2C(=C1)C(=CC=N2)C(=O)O
WGK Germany	3
RTECS	GD3850000
PubChem CID	10243
Molecular Weight	173.17
Beilstein	5224
Reaxy-Rn	5224

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number	Certificate Type	Date	Item
H1617020	Certificate of Analysis	Apr 07, 2024	Q123917
D23261195	Certificate of Analysis	May 12, 2023	Q123917
J2229516	Certificate of Analysis	Nov 02, 2022	Q123917

Chemical and Physical Properties

Melt Point(°C)	253-255°C
Molecular Weight	173.170 g/mol
XLogP3	0.500
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	1
Exact Mass	173.048 Da
Monoisotopic Mass	173.048 Da
Topological Polar Surface Area	50.200 Å²
Heavy Atom Count	13
Formal Charge	0
Complexity	205.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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