Basic Description

Synonyms	AC-10071 \| DB03148 \| InChI=1/C6H6OS/c7-5-1-3-6(8)4-2-5/h1-4,7-8H \| STL554392 \| p-hydroxybenzenethiol \| Phenol, 4-mercapto- \| S10242 \| 4-Mercaptophenol, Vetec(TM) reagent grade, 89% \| USAF B-57 \| para-hydroxy thiophenol \| Phenol, p-mercapto- \| NSC46192 \| N
Specifications & Purity	≥97%
Storage Temp	Argon charged
Shipped In	Normal
Product Description	4-Mercaptophenol (MPH) has been used to study the adsorption of MPH on silver coated polystyrene nanospheres by time-dependent surface-enhanced Raman scattering (SERS) spectroscopy. 4-Mercaptophenol may be used in the preparation of silylated monomer, which was employed for the synthesis of hyperbranched poly(ester-imide). 4-Mercaptophenol (H-4MP) reacts with metal tert-butoxides ([M(OBut)4]) to yield the following Group 4 phenoxy-thiols: · [(HOBut)(4MP)3M(μ-4MP)]2, where M = Ti, Zr, Hf · [(py)2M(4MP)], where M = Ti, Zr; py = pyridine · [(py)(4MP)3Hf(μ-4MP)]2 4-Mercaptophenol may be used in the synthesis of the following: · poly(ethersulfide)s via silylation followed by polycondensation with 2,6-dichloropyridine or 3,6-dichloropyridazine · 2,6-di-tertiarybutyl-4-mercaptophenol via Friedel-Craft’s alkylation with tert-butyl chloride in presence of a lewis acid

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - Class Thiophenols

Kingdom	Organic compounds
Superclass	Benzenoids
Class	Thiophenols
Subclass	Not available
Intermediate Tree Nodes	Not available
Direct Parent	Thiophenols
Alternative Parents	Thiohydroquinones 1-hydroxy-2-unsubstituted benzenoids Benzene and substituted derivatives Thiols Organooxygen compounds Hydrocarbon derivatives
Molecular Framework	Aromatic homomonocyclic compounds
Substituents	Thiophenol - Thiohydroquinone - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Monocyclic benzene moiety - Arylthiol - Organic oxygen compound - Hydrocarbon derivative - Organosulfur compound - Organooxygen compound - Aromatic homomonocyclic compound
Description	This compound belongs to the class of organic compounds known as thiophenols. These are compounds containing a thiophenol ring, which a phenol derivative obtained by replacing the oxygen atom from the hydroxyl group (attached to the benzene) by a sulfur atom.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

Pubchem Sid	504758038
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504758038
IUPAC Name	4-sulfanylphenol
INCHI	InChI=1S/C6H6OS/c7-5-1-3-6(8)4-2-5/h1-4,7-8H
InChIKey	BXAVKNRWVKUTLY-UHFFFAOYSA-N
Smiles	C1=CC(=CC=C1O)S
Isomeric SMILES	C1=CC(=CC=C1O)S
WGK Germany	3
RTECS	MX7175000
Molecular Weight	126.18
Beilstein	2039306
Reaxy-Rn	2039306
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2039306&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

12 results found

Lot Number	Certificate Type	Date	Item
E2513423	Certificate of Analysis	Mar 14, 2025	M101786
E2513424	Certificate of Analysis	Mar 14, 2025	M101786
E2513425	Certificate of Analysis	Mar 14, 2025	M101786
H2415026	Certificate of Analysis	Jul 12, 2024	M101786
L2111099	Certificate of Analysis	Sep 18, 2023	M101786
L2111100	Certificate of Analysis	Sep 18, 2023	M101786
L2111101	Certificate of Analysis	Sep 18, 2023	M101786
H2131399	Certificate of Analysis	Jun 06, 2023	M101786
C2508070	Certificate of Analysis	Jul 30, 2022	M101786
J2210569	Certificate of Analysis	Jul 30, 2022	M101786
J2210570	Certificate of Analysis	Jul 30, 2022	M101786
J2210571	Certificate of Analysis	Jul 30, 2022	M101786

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Chemical and Physical Properties

Solubility	Soluble in water.
Sensitivity	air ＆ Moisture sensitive
Freezing Point(°C)	34 °C
Flash Point(°F)	230 °F
Flash Point(°C)	110°C
Boil Point(°C)	149-150°C/25mmHg
Melt Point(°C)	33-35°C
Molecular Weight	126.180 g/mol
XLogP3	1.100
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	0
Exact Mass	126.014 Da
Monoisotopic Mass	126.014 Da
Topological Polar Surface Area	21.200 Å²
Heavy Atom Count	8
Formal Charge	0
Complexity	66.900
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Hao Jiang, Wuting Pang, Meng Cheng, Tong Yan, Zhikun Wang, Zhihao Zhao, Chunling Li, Shuangqing Sun, Songqing Hu. (2024) Construction and mechanism of phase-locked structured PU elastomers with tunable mechanical and self-healing properties. APPLIED SURFACE SCIENCE, 649 (159136).
2. Zhuoyao Li, Chengyu Zhang, Huixiang Sheng, Jin Wang, Yameng Zhu, Liuyingzi Yu, Junjie Wang, Qiming Peng, Gang Lu. (2022) Molecular Cocatalyst of p-Mercaptophenylboronic Acid Boosts the Plasmon-Mediated Reduction of p-Nitrothiophenol. ACS Applied Materials & Interfaces, 14 (33): (38302–38310).
3. Juanhua Zhang, Yuzhen Li, Mengxiao Lv, Yihui Bai, Zhenmin Liu, Xuexiang Weng, Chunping You. (2022) Determination of 5-Hydroxymethylfurfural (5-HMF) in milk products by surface-enhanced Raman spectroscopy and its simulation analysis. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 279 (121393).
4. Xin Zhang, Xin Xie, Lingjun Zhang, Kaibin Yao, Yingzhou Huang. (2022) Optoplasmonic MOFs film for SERS detection. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 278 (121362).
5. Xiaowei Huang, Ning Zhang, Zhihua Li, Jiyong Shi, Haroon Elrasheid Tahir, Yue Sun, Yang Zhang, Xinai Zhang, Melvin Holmes, Xiaobo Zou. (2022) Rapid Detection of Carbendazim Residue in Apple Using Surface-Enhanced Raman Scattering and Coupled Chemometric Algorithm. Foods, 11 (9): (1287).
6. Menghui Wan, Haodong Zhao, Zhihua Wang, Xueyan Zou, Yanbao Zhao, Lei Sun. (2021) Fabrication of Ag modified SiO2 electrospun nanofibrous membranes as ultrasensitive and high stable SERS substrates for multiple analytes detection. Colloid and Interface Science Communications, 42 (100428).
7. Jing He, Fenglei Shi, Jianbo Wu, Jian Ye. (2021) Shape Transformation Mechanism of Gallium–Indium Alloyed Liquid Metal Nanoparticles. Advanced Materials Interfaces, 8 (6): (2001874).
8. Menghui Wan, Haodong Zhao, Lichao Peng, Xueyan Zou, Yanbao Zhao, Lei Sun. (2020) Loading of Au/Ag Bimetallic Nanoparticles within and Outside of the Flexible SiO2 Electrospun Nanofibers as Highly Sensitive, Stable, Repeatable Substrates for Versatile and Trace SERS Detection. Polymers, 12 (12): (3008).
9. Chen Xuejing, Zhou Xuesi, He Qinghua, He Yonghong, Guan Tian, Feng Guangxia, Wang Bei, Xie Luyuan, Ji Yanhong. (2020) Hydrogel-based microbeads for Raman-encoded suspension array using the reversed-phase suspension polymerization method and ultraviolet light curing. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 412 (12): (2731-2741).
10. Li Yanzhou, Jiang Xiaoming, Fu Zhihua, Huang Qingqing, Wang Guan-E., Deng Wei-Hua, Wang Chen, Li Zhenzhu, Yin Wanjian, Chen Banglin, Xu Gang. (2020) Coordination assembly of 2D ordered organic metal chalcogenides with widely tunable electronic band gaps. Nature Communications, 11 (1): (1-9).
11. Xuejing Chen, Zhiyuan Shen, Yonghong He, Tian Guan, Qinghua He, Bei Wang, Luyuan Xie, Guangxia Feng, Bangrong Lu, Xuesi Zhou, Jiafan Liu, Zhigang Fan. (2019) Dual-wavelength digital holographic phase and fluorescence microscopy combining with Raman spectroscopy for micro-quartz pieces-based dual-channel encoded suspension array. OPTICS EXPRESS, 27 (3): (1894-1910).
12. Xuejing Chen, Qinghua He, Tian Guan, Yonghong He, Guangxia Feng, Bei Wang, Bangrong Lu, Yanhong Ji. (2019) Dual-digital encoded suspension array based on Raman spectroscopy and laser induced breakdown spectroscopy for multiplexed biodetection. SENSORS AND ACTUATORS B-CHEMICAL, 282 (457).
13. Yan Yang, Zhijie Zhang, Yali He, Zhihua Wang, Yanbao Zhao, Lei Sun. (2018) Fabrication of Ag@TiO2 electrospinning nanofibrous felts as SERS substrate for direct and sensitive bacterial detection. SENSORS AND ACTUATORS B-CHEMICAL, 273 (600).
14. Ruimin Li, Yuting Zhang, Jing Tan, Jiaxun Wan, Jia Guo, Changchun Wang. (2016) Dual-Mode Encoded Magnetic Composite Microsphere Based on Fluorescence Reporters and Raman Probes as Covert Tag for Anticounterfeiting Applications. ACS Applied Materials & Interfaces, 8 (14): (9384–9394).
15. Xinyuan Bi, Zhicheng He, Zhewen Luo, Wensi Huang, Xingxing Diao, Jian Ye. (2024) Digital colloid-enhanced Raman spectroscopy for the pharmacokinetic detection of bioorthogonal drugs. Chemical Science,
16. Haowen Luo, Yaoming Zhang, Zhuoxuan Lv, Shaozhen Luo, Yang Ou, Huidan Xue, Guan-E. Wang, Gang Xu, Jianxi Liu. (2025) Engineering surface functional groups of 2D organic metal chalcogenides to regulate lubrication performance across scales. TRIBOLOGY INTERNATIONAL, 204 (110420).

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SKU	Size	Availability	Price
M101786-5g	5g	1	$34.90
M101786-25g	25g	3	$132.90
M101786-100g	100g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$369.90

4-Mercaptophenol - 97%, high purity , CAS No.637-89-8