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4-Hydroxyphenylpyruvic acid - ≥95.0%(HPLC), high purity , CAS No.156-39-8

5 Citations

COA

Grade & Purity:

Moligand™

≥95%(HPLC)

Cas Number: 156-39-8
Molecular Weight: 180.16
Beilstein Registry Number: 2691632
EC Number: 205-852-9
MDL number: MFCD00002591
PubChem CID: 979
PubChem SID: 504750442

In stock

Item Number

H138306

Grouped product items
SKU	Size	Availability	Price
H138306-200mg	200mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$18.90
H138306-250mg	250mg	3	$20.90
H138306-1g	1g	3	$62.90
H138306-5g	5g	2	$183.90

View related series

carboxylic acid (2098) Metabolite (5307) Non heterocyclic block (8163)

Basic Description

Synonyms	3-(4-Hydroxyphenyl)-2-oxopropanoic acid \| 3-(4-hydroxyphenyl)-2-oxo-propanoic acid \| 87E988C4-F26C-4E03-9A40-1B0C0B36CA67 \| p-Hydroxyphenylpyruvic acid \| EN300-1855716 \| ENO \| MFCD00002591 \| 3-(4-Hydroxyphenyl)-2-oxopropanoicacid \| EINECS 205-852-9 \| p-Hy
Specifications & Purity	Moligand™, ≥95%(HPLC)
Storage Temp	Store at 2-8°C
Shipped In	Wet ice This product requires cold chain shipping. Ground and other economy services are not available.
Grade	Moligand™
Product Description	It can be determined in pork meat and Iberian ham samples by a sensitive method of multiple reaction monitoring (MRM) by mass spectrometry. 4-Hydroxyphenylpyruvic acid is an enzyme inhibitor. product description： 4-hydroxyphenylpyruvic acid can be determined in pork meat and Iberian ham samples by a sensitive method of multiple reaction monitoring (MRM) by mass spectrometry.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - Class Benzene and substituted derivatives
    - Subclass Phenylpyruvic acid derivatives

Kingdom	Organic compounds
Superclass	Benzenoids
Class	Benzene and substituted derivatives
Subclass	Phenylpyruvic acid derivatives
Intermediate Tree Nodes	Not available
Direct Parent	Phenylpyruvic acid derivatives
Alternative Parents	Phenylpropanoic acids 1-hydroxy-2-unsubstituted benzenoids Alpha-keto acids and derivatives Alpha-hydroxy ketones Monocarboxylic acids and derivatives Carboxylic acids Organic oxides Hydrocarbon derivatives
Molecular Framework	Aromatic homomonocyclic compounds
Substituents	Phenylpyruvate - 3-phenylpropanoic-acid - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Alpha-keto acid - Keto acid - Alpha-hydroxy ketone - Ketone - Carboxylic acid derivative - Carboxylic acid - Monocarboxylic acid or derivatives - Organic oxide - Organic oxygen compound - Carbonyl group - Hydrocarbon derivative - Organooxygen compound - Aromatic homomonocyclic compound
Description	This compound belongs to the class of organic compounds known as phenylpyruvic acid derivatives. These are compounds containing a phenylpyruvic acid moiety, which consists of a phenyl group substituted at the second position by an pyruvic acid.
External Descriptors	phenols - oxo carboxylic acid
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

MIF Tchem Macrophage migration inhibitory factor (979 Activities)

Discover Target: MIF

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Slc22a20 Solute carrier family 22 member 20 (86 Activities)

Discover Target: Slc22a20

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	504750442
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504750442
IUPAC Name	3-(4-hydroxyphenyl)-2-oxopropanoic acid
INCHI	InChI=1S/C9H8O4/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,10H,5H2,(H,12,13)
InChIKey	KKADPXVIOXHVKN-UHFFFAOYSA-N
Smiles	C1=CC(=CC=C1CC(=O)C(=O)O)O
Isomeric SMILES	C1=CC(=CC=C1CC(=O)C(=O)O)O
WGK Germany	3
RTECS	UZ1000000
Molecular Weight	180.16
Beilstein	2691632
Reaxy-Rn	2691632
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2691632&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

11 results found

Lot Number	Certificate Type	Date	Item
G2331219	Certificate of Analysis	May 12, 2025	H138306
G2331208	Certificate of Analysis	May 12, 2025	H138306
G2329555	Certificate of Analysis	May 12, 2025	H138306
G2331195	Certificate of Analysis	May 12, 2025	H138306
G2331197	Certificate of Analysis	May 12, 2025	H138306
G2331213	Certificate of Analysis	May 12, 2025	H138306
A2509270	Certificate of Analysis	Jul 11, 2024	H138306
A2509271	Certificate of Analysis	Jul 11, 2024	H138306
F2223142	Certificate of Analysis	Apr 03, 2024	H138306
F2223085	Certificate of Analysis	Apr 03, 2024	H138306
F2223143	Certificate of Analysis	Apr 03, 2024	H138306

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Chemical and Physical Properties

Solubility	Solubility in water: slightly soluble Solubility in other solvents: soluble in ether, alcohol, chloroform
Sensitivity	Heat sensitive
Melt Point(°C)	219-220 °C
Molecular Weight	180.160 g/mol
XLogP3	0.900
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Exact Mass	180.042 Da
Monoisotopic Mass	180.042 Da
Topological Polar Surface Area	74.600 Å²
Heavy Atom Count	13
Formal Charge	0
Complexity	204.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Jingling Guo, Pan Wang, Yifan Cui, Xiaosong Hu, Fang Chen, Chen Ma. (2023) Alleviation Effects of Microbial Metabolites from Resveratrol on Non-Alcoholic Fatty Liver Disease. Foods, 12 (1): (94).
2. Qihao Zhang, Xiaohui Yang, Lin Lin, Shuhong Wu, Ping Wang, Wei Wei, Dongzhi Wei. (2023) Pyomelanin production via heterologous expression of 4-hydroxyphenylpyruvate dioxygenase (HPPD) and construction of HPPD inhibitor screening model. JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 135 (93).
3. Ziyue Zhou, Renjiang Li, Ke Li, Kai Zong, Dongshun Deng. (2022) Efficient and reversible absorption of low pressure NH3 by functional type V deep eutectic solvents based on phenol and hydroxypyridine. NEW JOURNAL OF CHEMISTRY, 46 (45): (21730-21736).
4. Jinbin Liu, Kaipeng Wang, Mian Wang, Huaxiang Deng, Xiaodong Chen, Yueling Shang, Xiaochen Liu, Xiaohong Yu. (2022) Efficient whole cell biotransformation of tyrosol from L-tyrosine by engineered Escherichia coli. ENZYME AND MICROBIAL TECHNOLOGY, 160 (110100).
5. Wen-Kai Liu, Xiu-Xin Ren, Lian Xu, Juan Lin. (2025) Modular cascade with engineered HpaB for efficient synthesis of hydroxytyrosol. BIOORGANIC CHEMISTRY, (108125).

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