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| Synonyms | 4C1N 4-CN | 4-Chloro-1-naphthol, >=95.0% (HPLC), tablet (~32 mg each) | 4-Chloro-1-naphthol, for analytical purposes, >=99.0% | 4-chloronaphthol | Z104477546 | LVSPDZAGCBEQAV-UHFFFAOYSA- | C2291 | STR01788 | 1-chloro-4-naphthol | C-5180 | SY045975 | 1-Chl |
|---|---|
| Specifications & Purity | ≥99% |
| Biochemical and Physiological Mechanisms | Chromogenic peroxidase substrate that results in a precipitate that is blue to blue-purple in color and can be observed visually. Used for both western blotting and immunohistochemical staining. Can be used as a substitute in the myeloperoxidase stain for |
| Storage Temp | Store at -20°C,Argon charged |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
| Product Description |
4-Chloro-1-naphthol is primarily used for the detection of proteins, it gives a characteristic purple precipitate and the reactions are easily controllable. It can be used as a substitute for benzidine compounds, which are considered to be carcinogenic. |
Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Naphthalenes |
| Subclass | Naphthols and derivatives |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Naphthols and derivatives |
| Alternative Parents | Chloronaphthalenes 1-hydroxy-2-unsubstituted benzenoids Aryl chlorides Organooxygen compounds Organochlorides Hydrocarbon derivatives |
| Molecular Framework | Aromatic homopolycyclic compounds |
| Substituents | Chloronaphthalene - 1-naphthol - 1-hydroxy-2-unsubstituted benzenoid - Aryl halide - Aryl chloride - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Organochloride - Organohalogen compound - Aromatic homopolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as naphthols and derivatives. These are naphthalene derivatives carrying one or more hydroxyl (-OH) groups at any ring position. |
| External Descriptors | Not available |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| Pubchem Sid | 488181433 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488181433 |
| IUPAC Name | 4-chloronaphthalen-1-ol |
| INCHI | InChI=1S/C10H7ClO/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6,12H |
| InChIKey | LVSPDZAGCBEQAV-UHFFFAOYSA-N |
| Smiles | C1=CC=C2C(=C1)C(=CC=C2Cl)O |
| Isomeric SMILES | C1=CC=C2C(=C1)C(=CC=C2Cl)O |
| WGK Germany | 3 |
| Molecular Weight | 178.61 |
| Beilstein | 509750 |
| Reaxy-Rn | 509750 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=509750&ln= |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Mar 12, 2025 | C109038 | |
| Certificate of Analysis | Mar 20, 2023 | C109038 | |
| Certificate of Analysis | Mar 20, 2023 | C109038 | |
| Certificate of Analysis | Mar 20, 2023 | C109038 | |
| Certificate of Analysis | Mar 20, 2023 | C109038 | |
| Certificate of Analysis | Mar 20, 2023 | C109038 | |
| Certificate of Analysis | Mar 20, 2023 | C109038 |
| Solubility | Soluble in Methanol |
|---|---|
| Sensitivity | Air & Light Sensitive |
| Melt Point(°C) | 117-120°C |
| Molecular Weight | 178.610 g/mol |
| XLogP3 | 3.900 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 0 |
| Exact Mass | 178.019 Da |
| Monoisotopic Mass | 178.019 Da |
| Topological Polar Surface Area | 20.200 Ų |
| Heavy Atom Count | 12 |
| Formal Charge | 0 |
| Complexity | 160.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
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