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4-Aminobenzohydrazide - >98.0%(HPLC), high purity , CAS No.5351-17-7

3 Citations

COA

Grade & Purity:

≥98%(HPLC)

Cas Number: 5351-17-7
Poids moléculaire: 151.17
Beilstein Registry Number: 14(3)1081
MDL number: MFCD00007606
PubChem CID: 21450
PubChem SID: 488182697

En stock

Item Number

A151536

Articles du produit groupé
SKU	Taille	Disponibilité	Prix
A151536-1g	1g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	9,90$US
A151536-5g	5g	Available within 1-2 weeks(?) Item is derived from our semi-finished stock and is processed in 1-2 weeks.	13,90$US
A151536-25g	25g	Available within 1-2 weeks(?) Item is derived from our semi-finished stock and is processed in 1-2 weeks.	51,90$US
A151536-100g	100g	8	152,90$US
A151536-500g	500g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	684,90$US

Potent, irreversible and specific MPO inhibitor

View related series

Ferroptosis (356) Glucose Metabolism (1943) Glutathione Peroxidase (23) Hydrazide (61) Metabolic Enzyme/Protease (4860) Non heterocyclic block (8163)

Description générale

Synonymes	p-Aminobenzoyl hydrazide \| HY-B0880 \| STK075152 \| Z57199627 \| BB 0259293 \| AS-57471 \| EN300-18128 \| para-Aminobenzhydrazide \| SCHEMBL328628 \| 4-Aminobenzoic hydrazide \| BRN 0639053 \| SY036768 \| p-Aminobenzoic hydrazide \| 4NPhCON2 \| AKOS000119698 \| A1211 \|
Spécifications et pureté	≥98%(HPLC)
Mécanismes biochimiques et physiologiques	Potent, irreversible and specific MPO inhibitor (IC 50 = 300 nM). Benzoic acid analog. No inhibition of catalase or glutathione peroxidase activity. Inhibits apoptosis in vitro .
Température de stockage	Argon charged
Expédié en	Normal
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - Classe Benzene and substituted derivatives
    - Subclass Benzoic acids and derivatives

Kingdom	Organic compounds
Superclass	Benzenoids
Classe	Benzene and substituted derivatives
Subclass	Benzoic acids and derivatives
Intermediate Tree Nodes	Not available
Direct Parent	Aminobenzoic acids and derivatives
Alternative Parents	Benzoyl derivatives Aniline and substituted anilines Carboxylic acid hydrazides Amino acids and derivatives Primary amines Organopnictogen compounds Organooxygen compounds Organic oxides Hydrocarbon derivatives
Molecular Framework	Aromatic homomonocyclic compounds
Substituents	Aminobenzoic acid or derivatives - Benzoyl - Aniline or substituted anilines - Amino acid or derivatives - Carboxylic acid hydrazide - Carboxylic acid derivative - Amine - Primary amine - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Aromatic homomonocyclic compound
Description	This compound belongs to the class of organic compounds known as aminobenzoic acids and derivatives. These are benzoic acids (or derivative thereof) containing an amine group attached to the benzene moiety.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Cibles associées (humaines)

MPO Tchem Myeloperoxidase (2 Activities)

Discover Target: MPO

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MPO Tchem Myeloperoxidase (1002 Activities)

Discover Target: MPO

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Cibles associées (non humaines)

Mycobacterium tuberculosis (203094 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mécanismes d'action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	Références

Noms et identifiants

Pubchem Sid	488182697
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488182697
IUPAC Name	4-aminobenzohydrazide
INCHI	InChI=1S/C7H9N3O/c8-6-3-1-5(2-4-6)7(11)10-9/h1-4H,8-9H2,(H,10,11)
InChIKey	WPBZMCGPFHZRHJ-UHFFFAOYSA-N
Smiles	C1=CC(=CC=C1C(=O)NN)N
Isomères SMILES	C1=CC(=CC=C1C(=O)NN)N
WGK Allemagne	3
RTECS	DG2580000
Poids moléculaire	151.17
Beilstein	14(3)1081
Reaxy-Rn	639053
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=639053&ln=

Certificats (CoA, COO, BSE/TSE et tableau d'analyse)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot Number	Certificate Type	Date	Article
F2102112	Certificate of Analysis	Mar 04, 2025	A151536
F2102127	Certificate of Analysis	Mar 04, 2025	A151536
K2230126	Certificate of Analysis	Dec 07, 2022	A151536
L2418129	Certificate of Analysis	Aug 27, 2022	A151536
I2224009	Certificate of Analysis	Aug 27, 2022	A151536
I2224007	Certificate of Analysis	Aug 27, 2022	A151536
I2224010	Certificate of Analysis	Aug 27, 2022	A151536
I2224008	Certificate of Analysis	Aug 27, 2022	A151536
H2324288	Certificate of Analysis	Aug 27, 2022	A151536
C2330278	Certificate of Analysis	Apr 15, 2021	A151536

Propriétés chimiques et physiques

Solubilité	Soluble in DMSO (10 mg/ml), dilute acids, and water (partly miscible).
Sensibilité	air sensitive
Point de fusion (°C)	228 °C
Poids moléculaire	151.170 g/mol
XLogP3	-0.700
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	1
Exact Mass	151.075 Da
Monoisotopic Mass	151.075 Da
Topological Polar Surface Area	81.100 Å²
Heavy Atom Count	11
Formal Charge	0
Complexity	141.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Yan Zhao, Xinquan Yu, Xiao Liu, Dailiang Zhang, He Li, Hanlin Zhou, Weiheng Kong, Fengli Qu. (2023) ClO– Induced Dual-Excitation Fluorescent Probes Responding to Diverse Testing Modes with Ratio Methodology. ANALYTICAL CHEMISTRY, 95 (18): (7170–7177). [PMID:37114482] [10.1021/acs.analchem.2c05532]
2. Zhilan Pan, Yuli Wei, Hao Guo, Bingqing Liu, Lei Sun, Zongyan Lu, Xiaoqin Wei, Hao Zhang, Yuan Chen, Wu Yang. (2023) Sensitive detection of sulfamethoxazole by an electrochemical sensing platform with a covalent organic framework in situ grown on polyaniline. MICROPOROUS AND MESOPOROUS MATERIALS, 348 (112409). [PMID:] [10.1016/j.micromeso.2022.112409]
3. Haimei Yang, Qianghong Zhao, Xian Wang, Yu Wu, Yuchen Su, Weili Wei. (2021) Facile and highly selective sensing of hypochlorous acid in aqueous solution and living cells by using as-prepared WSe2 quantum dots. SENSORS AND ACTUATORS B-CHEMICAL, 337 (129782). [PMID:] [10.1016/j.snb.2021.129782]

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