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4-Aminoantipyrine - 10mM in DMSO, high purity , CAS No.83-07-8

    Grade & Purity:
  • 10mM in DMSO
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Item Number
A426146
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A426146-1ml
1ml
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$69.90

Basic Description

Synonyms 4-Aminoantipyrine | AMPYRONE | 83-07-8 | 4-Aminophenazone | Metapirazone | Aminoantipyrine | 4-Aminoantipyrene | Aminoantipyrin | Solvapyrin-A | Aminoazophene | Solnapyrin-A | Aminoazophenazone | 4-AAP | 4-Amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one | 3H-Pyrazol-3-one, 4-amino-1,2
Specifications & Purity 10mM in DMSO
Storage Temp Store at -80°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

4-Aminoantipyrine is a reagent for glucose determination in the presence of peroxidase and phenol.
A reagent for glucose determination in the presence of peroxidase and phenol

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organoheterocyclic compounds
Class Azoles
Subclass Pyrazoles
Intermediate Tree Nodes Not available
Direct Parent Phenylpyrazoles
Alternative Parents Pyrazolones  Benzene and substituted derivatives  Vinylogous amides  Heteroaromatic compounds  Lactams  Azacyclic compounds  Primary amines  Organopnictogen compounds  Organooxygen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular Framework Aromatic heteromonocyclic compounds
Substituents Phenylpyrazole - Monocyclic benzene moiety - Pyrazolinone - Benzenoid - Heteroaromatic compound - Vinylogous amide - Lactam - Azacycle - Amine - Hydrocarbon derivative - Organic oxide - Primary amine - Organopnictogen compound - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Aromatic heteromonocyclic compound
Description This compound belongs to the class of organic compounds known as phenylpyrazoles. These are compounds containing a phenylpyrazole skeleton, which consists of a pyrazole bound to a phenyl group.
External Descriptors primary amino compound - pyrazolone

Associated Targets(Human)

PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KAT2B Tchem Histone acetyltransferase PCAF (884 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GCN5 Histone acetyltransferase GCN5 (89 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TGR Thioredoxin glutathione reductase (28579 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

IUPAC Name 4-amino-1,5-dimethyl-2-phenylpyrazol-3-one
INCHI InChI=1S/C11H13N3O/c1-8-10(12)11(15)14(13(8)2)9-6-4-3-5-7-9/h3-7H,12H2,1-2H3
InChIKey RLFWWDJHLFCNIJ-UHFFFAOYSA-N
Smiles CC1=C(C(=O)N(N1C)C2=CC=CC=C2)N
Isomeric SMILES CC1=C(C(=O)N(N1C)C2=CC=CC=C2)N
WGK Germany 3
RTECS CD2480000
Molecular Weight 203.24
Beilstein 181635
Reaxy-Rn 181635
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=181635&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Sensitivity Light, Moisture and Air sensitive
Melt Point(°C) 109°C
Molecular Weight 203.240 g/mol
XLogP3 0.100
Hydrogen Bond Donor Count 1
Hydrogen Bond Acceptor Count 3
Rotatable Bond Count 1
Exact Mass 203.106 Da
Monoisotopic Mass 203.106 Da
Topological Polar Surface Area 49.600 Ų
Heavy Atom Count 15
Formal Charge 0
Complexity 305.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

1. Yifan Zeng, Shiyong Sun, Rui Lv, Ke Wang, Yevgeny Aleksandrovich Golubev, Sen Lin, Faqin Dong, Elena Leonidovna Kotova, Olga Borisovna Kotova.  (2024)  Construction of copper-manganese based aminoclays with significant laccase-like activity and its prominent degradation performance towards bisphenol A.  Journal of Environmental Chemical Engineering,  12  (111771). 
2. Yuxiang Yang, Xiaocui Huang, Mengyang Dong, Ziling Chang, Hongming Yuan, Yan Huang, Xiangnong Liu, Jianbo Zhang, Anbang Dai.  (2024)  Fe0Ni0 bimetal co-immobilized horseradish peroxidase on ZIF-8@HMON for degradation of trichloroacetic acid.  CHEMICAL ENGINEERING JOURNAL,  480  (147952). 
3. Wang Yunlong, Sun Yue, Wang Le, Zhang Hao, Hu Jiakang, Li Yongxin.  (2023)  Enhanced Removal of Phenols by MIZ-Cu Nanozyme Exhibiting Laccase-like Activity and Broader Adaptability to Temperature and pH Conditions.  CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,    (1-8). 
4. Qiuyan Zhao, Mingyue Ding, Dangshuai Pei, Xiuhua Qi, Yexuan Mao, Xianqing Huang, Lianjun Song, Jingnan Zuo, Huijuan Yang, Xiya Zhang.  (2023)  Development of a monoclonal antibody-based lateral flow immunoassay for the detection of benzoic acid in liquid food.  Analytical Methods,  15  (45): (6229-6238). 
5. Junhong Liu, Haifeng Wu, Yuanxi Liu, Zhen-Gang Wang.  (2023)  Colorimetric Sensor Based on the Oxidase-Mimic Supramolecular Catalyst for Selective and Sensitive Biomolecular Detection.  ACS Applied Materials & Interfaces,  15  (42): (48945–48951). 
6. Junjun Wang, Yue Tang, Jia Zheng, Zhengmin Xie, Jianli Zhou, Yuangen Wu.  (2024)  DNAzyme-based and smartphone-assisted colorimetric biosensor for ultrasensitive and highly selective detection of histamine in meats.  FOOD CHEMISTRY,  435  (137526). 
7. Xinrou Wang, Huan Liu, Cailin Qiao, Yi Ma, Huibo Luo, Changjun Hou, Danqun Huo.  (2024)  A dual-functional single-atom Fe nanozyme-based sensitive colorimetric sensor for tannins quantification in brandy.  FOOD CHEMISTRY,  434  (137523). 
8. Yu Wang, Qilin Zhao, Yu Xue, Donghui Wu, Bing Zhang, Jian Sun, Xiurong Yang.  (2023)  Protein-inorganic hybrid nanoflowers with laccase-like activity for specific assay of acetylcholinesterase activity.  SENSORS AND ACTUATORS B-CHEMICAL,  396  (134565). 
9. Zhongming Zhang, Enfang Gou, Zhiying Zhao, Jie Yao.  (2023)  Hydrophobically functionalized MIL-101/PEBA/PVDF composite membranes for phenol recovery by pervaporation.  SEPARATION AND PURIFICATION TECHNOLOGY,  327  (124900). 
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13. Wang Qi, Fu Hao, Qi Xiaoyu, Zhang Lei, Ma Hongyan.  (2023)  Immobilization of horseradish peroxidase with zwitterionic polymer material for industrial phenolic removal.  Biointerphases,  18  (4):  
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16. Huanxin Zhao, Yu Cao, Yuqi Liu, He Wang, Huixin Yu.  (2023)  Efficient degradation of phenol by MnOOH-rGO composite with high peroxymonosulfate utilization efficiency.  CHEMOSPHERE,  336  (139200). 
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18. Guangxu Bo, Liangcheng Jiao, Huanhuan Li, Guowei Zhao, Zitang Xu, Xiaoxiao Liu, Pengbo Wang, Xiaoke Tian, Jinyong Yan, Xueqing Wang, Yunjun Yan.  (2023)  Effective removal of phenol from polluted water via bio-based rigid polyurethane foams in collaboration with Alcaligenes faecalis.  Journal of Water Process Engineering,  53  (103876). 
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31. Liu Bolin, Wang Deqian, Yang Zihao, Zhao Yong, Xie Jing, Zhong Jian, Wang Zhengquan.  (2022)  Fabrication and characterization of 4-aminoantipyrine electrospun nanofiber polymer membranes for rapid visualization of pentachlorophenol in water samples.  Materials Express,  12  (8): (1126-1134). 
32. Jing Hu, Yun Luo, Min Hou, Jia Jia Qi, Li Li Liang, Wen Ge Li.  (2022)  Synthesis, structure, and anticancer studies of Cu (II) and Ni (II) complexes based on (5-chlorosalicylaldehyde)-4-aminoantipyrine Schiff base.  APPLIED ORGANOMETALLIC CHEMISTRY,  36  (10): (e6833). 
33. Shao-Bin He, Hui-Jing Yang, Liu Yang, Hamada A. A. Noreldeen, Hua-Ping Peng, Hao-Hua Deng, Wei Chen, Guo-Lin Hong.  (2022)  Rutin as a coenzyme of Fe-doped silicon nanozyme with enhanced peroxidase-like activity for a colorimetric β-glucuronidase sensor.  MICROCHEMICAL JOURNAL,  181  (107771). 
34. Quan Wang, Xiaoyu Wang, Hui Wei.  (2022)  Spinel-Oxide-Based Laccase Mimics for the Identification and Differentiation of Phenolic Pollutants.  ANALYTICAL CHEMISTRY,  94  (28): (10198–10205). 
35. Xiaoyu Yang, Lulu Lei, Donghui Song, Yue Sun, Meng Yang, Zhen Sang, Jianan Zhou, Hui Huang, Yongxin Li.  (2022)  An efficient differential sensing strategy for phenolic pollutants based on a nanozyme with polyphenol oxidase activity.  LUMINESCENCE,  37  (9): (1414-1426). 
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