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3,5-Bis[(2-fluorophenyl)methylene]-4-piperidinone , CAS No.342808-40-6

In stock
Item Number
B343498
Grouped product items
SKU Size
Availability
Price Qty
B343498-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$139.90
B343498-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$189.90
B343498-250mg
250mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$329.90
B343498-500mg
500mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$519.90

Basic Description

Synonyms 3,5-Bis[(2-fluorophenyl)methylene]-4-piperidinone | (3E,5E)-3,5-bis[(2-fluorophenyl)methylidene]piperidin-4-one;hydrochloride | EF24 | 3,5-bis((E)-2-fluorobenzylidene)piperidin-4-one hydrochloride | (3E,5E)-3,5-bis[(2-fluorophenyl)methylene]-4-piperidinon
Specifications & Purity Moligand™, ≥98%
Storage Temp Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade Moligand™
Product Description

EF24 is a curcumin analogue with greater anti-tumor efficacy and oral bioavailability via deactivation of the MAPK/ERK signaling pathway in oral squamous cell carcinoma (OSCC). EF24 treatment increases the levels of activated caspase 3 and 9, and decreases the phosphorylated forms of MEK1 and ERK.

Names and Identifiers

IUPAC Name (3E,5E)-3,5-bis[(2-fluorophenyl)methylidene]piperidin-4-one;hydrochloride
INCHI InChI=1S/C19H15F2NO.ClH/c20-17-7-3-1-5-13(17)9-15-11-22-12-16(19(15)23)10-14-6-2-4-8-18(14)21;/h1-10,22H,11-12H2;1H/b15-9+,16-10+;
InChIKey ILMJCEBAMHGBAA-XETSTSIRSA-N
Smiles C1C(=CC2=CC=CC=C2F)C(=O)C(=CC3=CC=CC=C3F)CN1.Cl
Isomeric SMILES C\1NC/C(=C\C2=CC=CC=C2F)/C(=O)/C1=C/C3=CC=CC=C3F.Cl
Molecular Weight 311.33
Reaxy-Rn 32927881
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=32927881&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot Number Certificate Type Date Item
F2520303 Certificate of Analysis Dec 09, 2024 B343498
F2520305 Certificate of Analysis Dec 09, 2024 B343498
F2520241 Certificate of Analysis Dec 09, 2024 B343498
F2520243 Certificate of Analysis Dec 09, 2024 B343498
F2520302 Certificate of Analysis Dec 09, 2024 B343498
F2520304 Certificate of Analysis Dec 09, 2024 B343498
F2520306 Certificate of Analysis Dec 09, 2024 B343498
F2520307 Certificate of Analysis Dec 09, 2024 B343498

Chemical and Physical Properties

Solubility DMSO: ≥10 mg/mL

Solution Calculators

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