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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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B343498-50mg
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50mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$139.90
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B343498-100mg
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100mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$189.90
|
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B343498-250mg
|
250mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$329.90
|
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B343498-500mg
|
500mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$519.90
|
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| Synonyms | 3,5-Bis[(2-fluorophenyl)methylene]-4-piperidinone | (3E,5E)-3,5-bis[(2-fluorophenyl)methylidene]piperidin-4-one;hydrochloride | EF24 | 3,5-bis((E)-2-fluorobenzylidene)piperidin-4-one hydrochloride | (3E,5E)-3,5-bis[(2-fluorophenyl)methylene]-4-piperidinon |
|---|---|
| Specifications & Purity | Moligand™, ≥98% |
| Storage Temp | Store at -20°C,Argon charged |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Grade | Moligand™ |
| Product Description |
EF24 is a curcumin analogue with greater anti-tumor efficacy and oral bioavailability via deactivation of the MAPK/ERK signaling pathway in oral squamous cell carcinoma (OSCC). EF24 treatment increases the levels of activated caspase 3 and 9, and decreases the phosphorylated forms of MEK1 and ERK.
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| IUPAC Name | (3E,5E)-3,5-bis[(2-fluorophenyl)methylidene]piperidin-4-one;hydrochloride |
|---|---|
| INCHI | InChI=1S/C19H15F2NO.ClH/c20-17-7-3-1-5-13(17)9-15-11-22-12-16(19(15)23)10-14-6-2-4-8-18(14)21;/h1-10,22H,11-12H2;1H/b15-9+,16-10+; |
| InChIKey | ILMJCEBAMHGBAA-XETSTSIRSA-N |
| Smiles | C1C(=CC2=CC=CC=C2F)C(=O)C(=CC3=CC=CC=C3F)CN1.Cl |
| Isomeric SMILES | C\1NC/C(=C\C2=CC=CC=C2F)/C(=O)/C1=C/C3=CC=CC=C3F.Cl |
| Molecular Weight | 311.33 |
| Reaxy-Rn | 32927881 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=32927881&ln= |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Dec 09, 2024 | B343498 | |
| Certificate of Analysis | Dec 09, 2024 | B343498 | |
| Certificate of Analysis | Dec 09, 2024 | B343498 | |
| Certificate of Analysis | Dec 09, 2024 | B343498 | |
| Certificate of Analysis | Dec 09, 2024 | B343498 | |
| Certificate of Analysis | Dec 09, 2024 | B343498 | |
| Certificate of Analysis | Dec 09, 2024 | B343498 | |
| Certificate of Analysis | Dec 09, 2024 | B343498 |
| Solubility | DMSO: ≥10 mg/mL |
|---|
Starting at $22.90