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3，4-dehydro-L-proline - ≥95.0%(HPLC), high purity , CAS No.4043-88-3

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3，4-dehydro-L-proline - ≥95.0%(HPLC), high purity , CAS No.4043-88-3

COA

Grade & Purity:

≥95%(HPLC)

Cas Number: 4043-88-3
Molecular Weight: 113.12
MDL number: MFCD00065964
PubChem CID: 94284
PubChem SID: 488186823

In stock

Item Number

D137596

Grouped product items
SKU	Size	Availability	Price
D137596-100mg	100mg	3	$106.90
D137596-250mg	250mg	3	$239.90
D137596-1g	1g	1	$638.90
D137596-5g	5g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,872.90

View related series

Five-Membered Heterocyclic Compounds (2064) Proline derivative (69)

Basic Description

Synonyms	(S)-2,5-Dihydro-1H-pyrrole-2-carboxylic acid \| L-3,4-Dehydroproline \| 3,4-Dehydro-L-proline \| BRN 5376764 \| L-3-Pyrroline-2-carboxylic acid \| (S)-3-Pyrroline-2-carboxylic acid \| Dehydro-proline \| (2S)-2,5-dihydro-1H-pyrrol-1-ium-2-carboxylate \| 3-(5-Nitro
Specifications & Purity	≥95%(HPLC)
Shipped In	Normal
Product Description	3,4-Dehydro-L-proline is used as a substrate and inhibitor of various enzymes. 3,4-Dehydro-L-proline may be used to inhibit extensin biosynthesis. 3,4-Dehydro-L-proline is a alternate substrate of the amino acid oxidase, NikD. 3,4-Dehydro-L-proline inhibits collagen secretion by chondorcytes.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic acids and derivatives
  - Class Carboxylic acids and derivatives
    - Subclass Amino acids, peptides, and analogues
      - Level5 Amino acids and derivatives
        Level6 Alpha amino acids and derivatives
        Level7 Alpha amino acids
        Level8 L-alpha-amino acids

Kingdom	Organic compounds
Superclass	Organic acids and derivatives
Class	Carboxylic acids and derivatives
Subclass	Amino acids, peptides, and analogues
Intermediate Tree Nodes	Amino acids and derivatives - Alpha amino acids and derivatives - Alpha amino acids
Direct Parent	L-alpha-amino acids
Alternative Parents	Pyrroline carboxylic acids Amino acids Monocarboxylic acids and derivatives Dialkylamines Carboxylic acids Azacyclic compounds Organopnictogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aliphatic heteromonocyclic compounds
Substituents	L-alpha-amino acid - Pyrroline carboxylic acid - Pyrroline carboxylic acid or derivatives - Pyrroline - Amino acid - Carboxylic acid - Secondary aliphatic amine - Monocarboxylic acid or derivatives - Secondary amine - Organoheterocyclic compound - Azacycle - Organic oxygen compound - Organic nitrogen compound - Organooxygen compound - Organonitrogen compound - Organopnictogen compound - Amine - Carbonyl group - Organic oxide - Hydrocarbon derivative - Aliphatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

GRIN1 Tclin Glutamate (NMDA) receptor subunit zeta 1 (122 Activities)

Discover Target: GRIN1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

EGLN1 Tclin Egl nine homolog 1 (1702 Activities)

Discover Target: EGLN1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HIF1AN Tbio Hypoxia-inducible factor 1-alpha inhibitor (79 Activities)

Discover Target: HIF1AN

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

GAP1 General amino-acid permease GAP1 (481 Activities)

Discover Target: GAP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	488186823
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488186823
IUPAC Name	(2S)-2,5-dihydro-1H-pyrrole-2-carboxylic acid
INCHI	InChI=1S/C5H7NO2/c7-5(8)4-2-1-3-6-4/h1-2,4,6H,3H2,(H,7,8)/t4-/m0/s1
InChIKey	OMGHIGVFLOPEHJ-BYPYZUCNSA-N
Smiles	C1C=CC(N1)C(=O)O
Isomeric SMILES	C1C=C[C@H](N1)C(=O)O
WGK Germany	3
RTECS	UX9371345
Molecular Weight	113.12
Reaxy-Rn	471693
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=471693&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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3 results found

Lot Number	Certificate Type	Date	Item
F1910052	Certificate of Analysis	Jan 09, 2023	D137596
L22071157	Certificate of Analysis	Dec 15, 2022	D137596
F2325368	Certificate of Analysis	Dec 15, 2022	D137596

Chemical and Physical Properties

Solubility	clear colorless solution at 50 MG/ML in acetic acid
Specific Rotation[α]	-380.0 to -410.0 deg(C=1, H2O)
Melt Point(°C)	217 °C(dec.)
Molecular Weight	113.110 g/mol
XLogP3	-2.500
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	1
Exact Mass	113.048 Da
Monoisotopic Mass	113.048 Da
Topological Polar Surface Area	49.300 Å²
Heavy Atom Count	8
Formal Charge	0
Complexity	130.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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