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3,3'-Dihydroxybenzidine - 98%, high purity , CAS No.2373-98-0

9 Citations COA COA
    Grade & Purity:
  • ≥98%
In stock
Item Number
D122452
Grouped product items
SKU Size
Availability
 Price Qty
D122452-1g
1g
3
$34.90
D122452-5g
5g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$132.90
D122452-25g
25g
3
$522.90
D122452-100g
100g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$1,499.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet
View related series
Diamine monomer (21) Polymer / polymer reagent (675)

Basic Description

Synonyms InChI=1/C12H12N2O2/c13-9-3-1-7(5-11(9)15)8-2-4-10(14)12(16)6-8/h1-6,15-16H,13-14H2 | 3,3'-dihydroxy-4,4'-diamino-bipheny | SY052119 | 3,3'-Dihydroxy-4,4'-diaminobiphenyl | 3,3'-Dihydroxy-4,4'-diamino-biphenyl | CCRIS 9225 | Q27285684 | ZGDMDBHLKNQPSD-UHFF
Specifications & Purity ≥98%
Storage Temp Argon charged
Shipped In Normal

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Benzenoids
Class Benzene and substituted derivatives
Subclass Biphenyls and derivatives
Intermediate Tree Nodes Benzidines
Direct Parent 3,3'-disubstituted benzidines
Alternative Parents o-Aminophenols  Aniline and substituted anilines  1-hydroxy-4-unsubstituted benzenoids  1-hydroxy-2-unsubstituted benzenoids  Primary amines  Organopnictogen compounds  Organooxygen compounds  Hydrocarbon derivatives  
Molecular Framework Aromatic homomonocyclic compounds
Substituents 3,3'-disubstituted benzidine - Aminophenol - O-aminophenol - Aniline or substituted anilines - Phenol - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Organic nitrogen compound - Primary amine - Amine - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Organopnictogen compound - Organic oxygen compound - Aromatic homomonocyclic compound
Description This compound belongs to the class of organic compounds known as 3,3'-disubstituted benzidines. These are organic compounds containing a benzidine skeleton, which is substituted only at the 3- and 3'-positions.
External Descriptors Not available

Associated Targets(Human)

NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
RXRA Tclin Retinoid X receptor alpha (3637 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
NFKB1 Tclin Nuclear factor NF-kappa-B p105 subunit (1459 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALOX15 Tchem Arachidonate 15-lipoxygenase (7108 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Lymphoblastoid cell (5959 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Cruzipain (33337 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Ppard Peroxisome proliferator-activated receptor delta (358 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

IUPAC Name 2-amino-5-(4-amino-3-hydroxyphenyl)phenol
INCHI InChI=1S/C12H12N2O2/c13-9-3-1-7(5-11(9)15)8-2-4-10(14)12(16)6-8/h1-6,15-16H,13-14H2
InChIKey ZGDMDBHLKNQPSD-UHFFFAOYSA-N
Smiles C1=CC(=C(C=C1C2=CC(=C(C=C2)N)O)O)N
Isomeric SMILES C1=CC(=C(C=C1C2=CC(=C(C=C2)N)O)O)N
RTECS DV4900000
Molecular Weight 216.24
Beilstein 13(2)502
Reaxy-Rn 2725972
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2725972&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

15 results found

Lot Number Certificate Type Date Item
F2510210 Certificate of Analysis Jun 24, 2025 D122452
A2508101 Certificate of Analysis Jan 15, 2025 D122452
D2402184 Certificate of Analysis Apr 15, 2024 D122452
D2402185 Certificate of Analysis Apr 15, 2024 D122452
D2402437 Certificate of Analysis Apr 15, 2024 D122452
D2402186 Certificate of Analysis Apr 15, 2024 D122452
B2225221 Certificate of Analysis Dec 11, 2023 D122452
B2225220 Certificate of Analysis Dec 11, 2023 D122452
B2225231 Certificate of Analysis Dec 11, 2023 D122452
A2205085 Certificate of Analysis Oct 20, 2023 D122452
D2115323 Certificate of Analysis Jan 13, 2023 D122452
J2227283 Certificate of Analysis Oct 31, 2022 D122452
J2227302 Certificate of Analysis Oct 31, 2022 D122452
J2227287 Certificate of Analysis Oct 31, 2022 D122452
I2227114 Certificate of Analysis Sep 30, 2022 D122452

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Chemical and Physical Properties

Solubility Insoluble in water; Soluble in Dimethylformamide
Sensitivity air sensitive
Melt Point(°C) 292°C
Molecular Weight 216.240 g/mol
XLogP3 1.500
Hydrogen Bond Donor Count 4
Hydrogen Bond Acceptor Count 4
Rotatable Bond Count 1
Exact Mass 216.09 Da
Monoisotopic Mass 216.09 Da
Topological Polar Surface Area 92.500 Ų
Heavy Atom Count 16
Formal Charge 0
Complexity 213.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

How to Cite Aladdin Scientific Products?
1. Zenghui Xie, Yuling Hu, Jiana Lin, Gongke Li, Qisheng Zhong.  (2023)  Calix[4]arene-based covalent organic frameworks with host-guest recognition for selective adsorption of six per- and polyfluoroalkyl substances in food followed by UHPLC-MS/MS detection.  JOURNAL OF HAZARDOUS MATERIALS,  459  (132198). 
2. Lili Zhang, Xinghua Zhang, Xinghai Wei, Deqi Jing, Weiguo Su, Shouchun Zhang.  (2022)  Hydroxyl-functionalized block co-polyimide enables simultaneously improved toughness and strength of tetrafunctional epoxy resin.  COMPOSITES SCIENCE AND TECHNOLOGY,  230  (109787). 
3. Jinmin Wang, Limin Zhao, Bing Yan.  (2022)  Postsynthetic functionalization of covalent organic frameworks for dual channel fluorescence diagnosis of two indicators related to Parkinson's disease.  SENSORS AND ACTUATORS B-CHEMICAL,  355  (131297). 
4. Xiao Zhang, Qin Yang, Yunhe Lang, Xia Jiang, Peng Wu.  (2020)  Rationale of 3,3′,5,5′-Tetramethylbenzidine as the Chromogenic Substrate in Colorimetric Analysis.  ANALYTICAL CHEMISTRY,  92  (18): (12400–12406). 
5. Zheng Hu, Yuhang Yang, Zhe Li, Qiuying Tao, Yinghong Huang, Xian Wang.  (2025)  Efficient enrichment and sensitive determination of endocrine disruptors in PPCPs by novel magnetic covalent organic framework extraction coupled with HPLC-MS/MS.  TALANTA,  287  (127667). 
6. Rusong Sang, Yezi Hu, Zewen Shen, Guixia Zhao, Junrong Yue, Xiubing Huang.  (2024)  Low-temperature synthesis of porous organic polymers with donor–acceptor structure and β-ketoenamine for photocatalytic oxidative coupling of amines.  Nanoscale,  16  (18): (8931-8940). 
7. Chunyi Yu, Xujing Kong, Wenting Li, Boyu Li, Baorong Chen, Mengyao Gao, Susu Cai, Yun Wei.  (2025)  Magnetic molecularly imprinted polymers coupled with UPLC-MS/MS for simultaneous detection of 19 steroid hormones in human plasma.  JOURNAL OF CHROMATOGRAPHY A,    (465655). 
8. Manyan Qiu, Yueling Tian, Wenxuan Qu, Yu Ma, Feng Zhao, Yujun Jiang, Qianyu Zhao, Chaoxin Man.  (2025)  Postbiotic-biosynthesized silver nanoparticles anchored on covalent organic frameworks integrated into carboxymethyl chitosan-based film for enhancing antibacterial packaging.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  291  (139143). 
9. Chenglong Sun, Ying Han, Hongyu Guo, Rui Zhao, Youxing Liu, Zheng Lin, Zehao Xiao, Zongqiang Sun, Mingchuan Luo, Shaojun Guo.  (2025)  Proton Reservoir in Covalent Organic Framework Compensating Oxygen Reduction Reaction Enhances Hydrogen Peroxide Photosynthesis.  ADVANCED MATERIALS,    (2502990). 

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