Basic Description

Synonyms	5-17-01-00078 (Beilstein Handbook Reference) \| Furan, tetrahydromethyl- \| NCGC00090914-01 \| tetrahydromethylfuran \| 2-METHYLTETRAHYDROFURAN [MI] \| 2-Methyltetrahydrofuran, stabilized, anhydrous, water Max 20ppm \| CCRIS 8717 \| Methyl tetrahydrofurane \| EIN
Specifications & Purity	anhydrous, ≥99%, Inhibitor-free
Shipped In	Normal
Grade	anhydrous

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Tetrahydrofurans

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Tetrahydrofurans
Subclass	Not available
Intermediate Tree Nodes	Not available
Direct Parent	Tetrahydrofurans
Alternative Parents	Oxacyclic compounds Dialkyl ethers Hydrocarbon derivatives
Molecular Framework	Aliphatic heteromonocyclic compounds
Substituents	Tetrahydrofuran - Oxacycle - Ether - Dialkyl ether - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Aliphatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as tetrahydrofurans. These are heterocyclic compounds containing a saturated, aliphatic, five-membered ring where a carbon is replaced by an oxygen.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)

Discover Target: PPARG

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

lef Anthrax lethal factor (7585 Activities)

Discover Target: lef

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	504751297
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504751297
IUPAC Name	2-methyloxolane
INCHI	InChI=1S/C5H10O/c1-5-3-2-4-6-5/h5H,2-4H2,1H3
InChIKey	JWUJQDFVADABEY-UHFFFAOYSA-N
Smiles	CC1CCCO1
Isomeric SMILES	CC1CCCO1
WGK Germany	2
RTECS	LU2800000
UN Number	2536
Molecular Weight	86.13
Beilstein	102448
Reaxy-Rn	102448
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=102448&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

33 results found

Lot Number	Certificate Type	Date	Item
F2511409	Certificate of Analysis	May 16, 2025	M298963
F2511560	Certificate of Analysis	May 16, 2025	M298963
F2511408	Certificate of Analysis	May 16, 2025	M298963
J2422668	Certificate of Analysis	Oct 16, 2024	M298963
J2422667	Certificate of Analysis	Oct 16, 2024	M298963
J2422669	Certificate of Analysis	Oct 16, 2024	M298963
J2422675	Certificate of Analysis	Oct 16, 2024	M298963
D2526018	Certificate of Analysis	Oct 16, 2024	M298963
J2422674	Certificate of Analysis	Oct 16, 2024	M298963
I2425194	Certificate of Analysis	Apr 10, 2023	M298963
C2419210	Certificate of Analysis	Apr 10, 2023	M298963
E2323810	Certificate of Analysis	Apr 10, 2023	M298963
E2323814	Certificate of Analysis	Apr 10, 2023	M298963
J2423244	Certificate of Analysis	Apr 10, 2023	M298963
E23231051	Certificate of Analysis	Apr 10, 2023	M298963
E2323950	Certificate of Analysis	Apr 10, 2023	M298963
D2301626	Certificate of Analysis	Mar 27, 2023	M298963
D2301630	Certificate of Analysis	Mar 27, 2023	M298963
D2301631	Certificate of Analysis	Mar 27, 2023	M298963
B2307604	Certificate of Analysis	Jan 31, 2023	M298963
B2307709	Certificate of Analysis	Jan 31, 2023	M298963
B2307413	Certificate of Analysis	Jan 31, 2023	M298963
B2307705	Certificate of Analysis	Jan 31, 2023	M298963
B2307712	Certificate of Analysis	Jan 31, 2023	M298963
J2218202	Certificate of Analysis	Sep 26, 2022	M298963
J2218203	Certificate of Analysis	Sep 26, 2022	M298963
J2218204	Certificate of Analysis	Sep 26, 2022	M298963
J2218205	Certificate of Analysis	Sep 26, 2022	M298963
A2309492	Certificate of Analysis	Sep 26, 2022	M298963
H2202325	Certificate of Analysis	Jul 28, 2022	M298963
H2202326	Certificate of Analysis	Jul 28, 2022	M298963
H2202327	Certificate of Analysis	Jul 28, 2022	M298963
H2202328	Certificate of Analysis	Jul 28, 2022	M298963

Show more⌵

Chemical and Physical Properties

Sensitivity	Air Sensitive
Refractive Index	1.4025
Flash Point(°F)	14 °F
Flash Point(°C)	-11℃
Boil Point(°C)	80.2°C
Molecular Weight	86.130 g/mol
XLogP3	1.000
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	0
Exact Mass	86.0732 Da
Monoisotopic Mass	86.0732 Da
Topological Polar Surface Area	9.200 Å²
Heavy Atom Count	6
Formal Charge	0
Complexity	43.200
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Peipei Lai, Chunzheng Liu, Zhuo Sun, Zhejuan Zhang. (2023) A highly effective and controllable chemical prelithiation of Silicon/Carbon/Graphite composite anodes for lithium-ion batteries. SOLID STATE IONICS, 403 (116415).
2. Liang Tan, Yijin Wu, Deliang Cheng, Renzong Hu. (2023) Tailoring electrolytes for Sn-based anodes toward Li storage at a low temperature of -50°C. ELECTROCHIMICA ACTA, 469 (143225).
3. Xin Li, Cancan Bian, Jun Zhang, Jian Hong, Rusheng Fu, Xufeng Zhou, Zhaoping Liu, Guangjie Shao. (2023) Chemical Pre-lithiation of SiOx Anodes with a Weakly Solvating Solution of Polycyclic Aromatic Hydrocarbons for Lithium-Ion Batteries. ACS Applied Energy Materials, 6 (17): (8919–8928).
4. Zhuangzhuang Chen, Yuqing Ma, Ning Fang, Min Ge, Yuan Su, An Chen, Shuai Yu, Ting Cai. (2023) Solid-liquid phase equilibrium and thermodynamic properties analysis of Bazedoxifene acetate in fifteen kinds of mono-solvents. JOURNAL OF CHEMICAL THERMODYNAMICS, 186 (107145).
5. Zhengming Xu, Shuang Liu, Huining Lai, Lijun You, Zhengang Zhao. (2023) Green-Efficient Enzymatic Synthesis and Characterization of Liposoluble 6′/6″-O-Lauryl Phenolic Glycosides with Enhanced Intestinal Permeability. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 71 (20): (7689–7702).
6. Xin Xu, Kai Wang, Yubo Zhou, Chenhuan Lai, Daihui Zhang, Changlei Xia, Arivalagan Pugazhendhi. (2023) Comparison of organosolv pretreatment of masson pine with different solvents in promoting delignification and enzymatic hydrolysis efficiency. FUEL, 338 (127361).
7. Zhengliang Zhang, Zhiwei Zhang, Xubin Zhang, Fumin Wang, Zheng Wang, Yongwang Li, Xingtao Wang, Rosine Ahishakiye, Xu Zhang. (2023) Single pot selective conversion of furfural into 2-methylfuran over a Co-CoOx/AC bifunctional catalyst. APPLIED SURFACE SCIENCE, 612 (155871).
8. Zhongbao Ma, Long-Fei Ren, Diwen Ying, Jinping Jia, Jiahui Shao. (2023) Dual-layer Janus charged nanofiltration membranes constructed by sequential electrospray polymerization for efficient water softening. CHEMOSPHERE, 310 (136929).
9. Yang Peng, Zhanwei Xu, Le Yu, Xucheng Li, Weiran Yang. (2023) Trimetallic Cu-Ni-Re/Hβ catalyst for the direct conversion of furfural to 2-Methyltetrahydrofuran. CHEMICAL ENGINEERING JOURNAL, 454 (139746).
10. Xin-Xin Fu, Jian-Peng Li, Zhuo-Qian Li, Yan Liu, Chen-Xiao Feng, Hai-Yang Wang, Zhi-Peng Zhao, Qiao-Yun Liu, Zhong-Yi Liu, Zhi-Kun Peng. (2022) Selective conversion of 2-methylfuran to 3-acetyl-1-propanol in water over Pd@HZSM-5 catalyst with balanced metal-acid cooperation. JOURNAL OF CATALYSIS, 413 (648).
11. Rulin Yang, Guangqiang Xu, Bingzhe Dong, Xuanhua Guo, Qinggang Wang. (2022) Selective, Sequential, and “One-Pot” Depolymerization Strategies for Chemical Recycling of Commercial Plastics and Mixed Plastics. ACS Sustainable Chemistry & Engineering, 10 (30): (9860–9871).
12. Zhongbao Ma, Long-Fei Ren, Diwen Ying, Jinping Jia, Jiahui Shao. (2022) Sustainable electrospray polymerization fabrication of thin-film composite polyamide nanofiltration membranes for heavy metal removal. DESALINATION, 539 (115952).
13. Yang Luo, Yicheng Deng, Yifei Shen, Hui Li, Yuliang Cao, Xinping Ai. (2022) A Facile and Efficient Chemical Prelithiation of Graphite for Full Capacity Utilization of Li-Ion Batteries. Energy Technology, 10 (7): (2200269).
14. Haoxiang Zhu, Youdi Zhang, Xusheng Guo, Youwei Cheng, Lijun Wang, Xi Li. (2022) Efficient One-Pot Production of 5-Hydroxymethylfurfural from Glucose in an Acetone–Water Solvent. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 61 (16): (5661–5671).
15. Li-Li Sun, Zhuang Yue, Shao-Chao Sun, Shao-Ni Sun, Xue-Fei Cao, Tong-Qi Yuan, Jia-Long Wen. (2022) Exploration of deep eutectic solvent-based biphasic system for furfural production and enhancing enzymatic hydrolysis: Chemical, topochemical, and morphological changes. BIORESOURCE TECHNOLOGY, 352 (127074).
16. Yifei Shen, Xiaohui Shen, Mei Yang, Jiangfeng Qian, Yuliang Cao, Hanxi Yang, Yang Luo, Xinping Ai. (2021) Achieving Desirable Initial Coulombic Efficiencies and Full Capacity Utilization of Li-Ion Batteries by Chemical Prelithiation of Graphite Anode. ADVANCED FUNCTIONAL MATERIALS, 31 (24): (2101181).
17. Qi Zhao, Hui Ma, Christian M. Pedersen, Mengyu Dou, Yan Qiao, Xianglin Hou, Yongqin Qi, Yingxiong Wang. (2021) Pure Shift NMR: Application of 1D PSYCHE and 1D TOCSY-PSYCHE Techniques for Directly Analyzing the Mixtures from Biomass-Derived Platform Compound Hydrogenation/Hydrogenolysis. ACS Sustainable Chemistry & Engineering, 9 (6): (2456–2464).
18. Zhen Cheng, Lei Ni, Junjie Wang, Juncheng Jiang, Hang Yao, Qiang Chen, Fusheng Cui, Wei Jiang, Shuliang Ye. (2021) Process hazard evaluation and exothermic mechanism for the synthesis of n-butylmagnesium bromide Grignard reagent in different solvents. PROCESS SAFETY AND ENVIRONMENTAL PROTECTION, 147 (654).
19. Xingfei Tang, Wentao Ding, Hao Li. (2021) Improved hydrodeoxygenation of bio-oil model compounds with polymethylhydrosiloxane by Brønsted acidic zeolites. FUEL, 290 (119883).
20. Yanhong Bi, Zhaoyu Wang, Rui Zhang, Yihan Diao, Yaoqi Tian, Zhengyu Jin. (2020) Improved Catalytic Properties of Thermomyces lanuginosus Lipase Immobilized onto Newly Fabricated Polydopamine-Functionalized Magnetic Fe3O4 Nanoparticles. Processes, 8 (5): (629).
21. Fei Peng, Ying Zhao, Fang-Zhou Li, Xiao-Yang Ou, Ying-Jie Zeng, Min-Hua Zong, Wen-Yong Lou. (2020) Highly enantioselective resolution of racemic 1-phenyl-1,2-ethanediol to (S)-1-phenyl-1,2-ethanediol by Kurthia gibsonii SC0312 in a biphasic system. JOURNAL OF BIOTECHNOLOGY, 308 (21).
22. Lele Jin, Wenzhi Li, Qiying Liu, Longlong Ma, Song Li, Yang Liu, Baikai Zhang, Qi Zhang. (2019) Catalytic conversion of cellulose to C5/C6 alkanes over Ir-VOx/SO2 combined with HZSM-5 in n-dodecane/water system. FUEL PROCESSING TECHNOLOGY, 196 (106161).
23. Siquan Xu, Donghui Pan, Feng Hu, Yuanfeng Wu, Huazheng Wang, Yuan Chen, Hui Yuan, Lijing Gao, Guomin Xiao. (2019) Highly efficient Cr/β zeolite catalyst for conversion of carbohydrates into 5‑hydroxymethylfurfural: Characterization and performance. FUEL PROCESSING TECHNOLOGY, 190 (38).
24. Siquan Xu, Donghui Pan, Yuanfeng Wu, Xianghai Song, Lijing Gao, Wenqi Li, Lalitendu Das, Guomin Xiao. (2018) Efficient production of furfural from xylose and wheat straw by bifunctional chromium phosphate catalyst in biphasic systems. FUEL PROCESSING TECHNOLOGY, 175 (90).
25. Zihao Zhang, Zehua Pei, Hao Chen, Kequan Chen, Zhaoyin Hou, Xiuyang Lu, Pingkai Ouyang, Jie Fu. (2018) Catalytic in-Situ Hydrogenation of Furfural over Bimetallic Cu–Ni Alloy Catalysts in Isopropanol. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 57 (12): (4225–4230).
26. Zexiang Lyu, Fen-e Gao, Lizhu Wen, Kemeng Shi, Minjun Ma, Chunju Li, Yingxiong Wang, Yan Qiao. (2018) DOSY Plus Selective TOCSY: An Efficient NMR Combination for Analyzing Hydrogenation/Hydrogenolysis Mixtures of Biomass-Derived Platform Compounds. ENERGY & FUELS, 32 (3): (3551–3558).
27. Chao Wang, Qilin Zhang, Yanglei Chen, Xueming Zhang, Feng Xu. (2018) Highly Efficient Conversion of Xylose Residues to Levulinic Acid over FeCl3 Catalyst in Green Salt Solutions. ACS Sustainable Chemistry & Engineering, 6 (3): (3154–3161).
28. Zhao-Yu Wang, Yan-Hong Bi, Rong-Ling Yang, Xiang-Jie Zhao, Ling Jiang, Cheng-Xin Ding, Shang-Yong Zheng. (2017) Highly efficient enzymatic synthesis of novel polydatin prodrugs with potential anticancer activity. PROCESS BIOCHEMISTRY, 52 (209).
29. Jingshan Wang, Xibin Wang, Xiangshan Fan, Kangkang Yang, Yingjia Zhang. (2016) An ignition delay time and kinetic study of 2-methyltetrahydrofuran at high temperatures. FUEL, 186 (758).
30. Xiudong Zhang,Yuanyuan Bai,Xuefei Cao,Runcang Sun. (2017-04-23) Pretreatment of Eucalyptus in biphasic system for furfural production and accelerated enzymatic hydrolysis.. Bioresource technology, 238 (1-6).
31. Wenju Wang,Junli Ren,Huiling Li,Aojie Deng,Runcang Sun. (2015-03-07) Direct transformation of xylan-type hemicelluloses to furfural via SnCl₄ catalysts in aqueous and biphasic systems.. Bioresource technology, 183 (188-194).
32. Yumeng Wang, Boyu Du, Qian Zheng, Xiaohong Chen. (2024) A demethylated lignin improved PVA-based supramolecular plastic with tough, degradable, and water-resistant performances. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 276 (133610).
33. Liao Xuan-Ping, Wu Qian, Zong Min-Hua, Li Ning. (2024) A straightforward chemobiocatalytic route for one-pot valorization of glucose into 2,5-bis(hydroxymethyl)furan. Bioresources and Bioprocessing, 11 (1): (1-10).
34. Jun Zhang, Yaoxin Xiao, Rui Shan, Haoran Yuan, Yong Chen. (2024) Calcium decorated Copper@Nitrogen-Doped carbon towards highly selective hydrogenation of biomass derived furfural. FUEL, 362 (130829).
35. Wenguang Li, Shubin Wu. (2025) Depolymerization and product evolution of kraft lignin in a novel acid deep eutectic solvents (DESs). INDUSTRIAL CROPS AND PRODUCTS, 225 (120476).
36. Zhou Luxiao, Gao Kun, He Peng, Yu Huahua, Xing Ronge, Liu Song, Qin Yukun. (2024) Efficient conversion of chitin to HMF under the co-catalytic system of formic acid and silicotungstic acid. Journal of Oceanology and Limnology, (1-13).
37. Chunlei Li, Junwei Zhang, Jinlong Sun, Yanjun Zhao, Junfei Zhou, Hui Wang, Yijie Yao, Ling Hu, Junlong Zhu, Ningshuang Zhang, Lijuan Zhang, Shiyou Li, Dongni Zhao. (2024) Electronic effect tuned ion-dipole interactions for low-temperature electrolyte design of LiFePO4-based lithium-ion batteries. Journal of Energy Storage, 102 (114207).
38. Kang Zhou, Yongsheng Zhang, Mengyuan Zhang, Armin Rezayan, Zhen Quan, Dandan Han, Jianshe Wang, Dan Wu, Chunbao Xu. (2024) Highly efficient conversion of biomass-derived furanic compounds into alkyl diols by selective hydrogenolysis using non-noble metal catalysts with tunable surface oxygen vacancies. CHEMICAL ENGINEERING JOURNAL, 492 (152347).
39. Dan Hu, Caiyun Wu, Qiubo He, Shuju Zhang, Shiquan Wang, Rong Zeng, Yanqing Zhang, Jianwen Liu. (2025) Novel strategies for constructing highly efficient silicon/carbon anodes: Chemical prelithiation and electrolyte post-treatment. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 688 (215).
40. Wu Bei, Liu Xiaocheng, Liu Peigen, Wu Geng, Tian Lin, Han Xiao, Li Junmin, Hong Xun. (2025) Synthesis of amorphous metal oxides via a crystalline to amorphous phase transition strategy. Nature Synthesis, (1-10).
41. Fengyao Cong, Zhenjie Yu, Aiqin Wang, Yu Cong, Tao Zhang, Ning Li. (2024) Synthesis of jet fuel range paraffins from cellulose. Sustainable Energy & Fuels,

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions, always use the batch-specific molecular weight of the product found on the vial label and the Certificate of Analysis (available online).

Dilution Calculator

Determine the dilution needed to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator enables you to quickly determine the volume of a reagent needed to reconstitute your vial. Just enter the mass of the reagent and the target concentration, and the calculator will do the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

SKU	Size	Availability	Price	Qty
M298963-100ml	100ml	3	$175.90
M298963-500ml	500ml	3	$349.90

2-Methyltetrahydrofuran - anhydrous, ≥99%, Inhibitor-free, high purity , CAS No.96-47-9