Basic Description

Synonyms	p-Propylguaiacol \| Propylguaiacol, p- \| A819218 \| 4-hydroxy-3-methoxypropyl benzene \| 4-propyl guaicol \| CAA78587 \| 1-Propyl-3-methoxy-4-hydroxybenzene \| 4-06-00-05976 (Beilstein Handbook Reference) \| eugenyl dihydro \| VS-02191 \| WLN: QR D3 BO1 \| CAS-2785
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Odor at 1.0% Taste at 10 ppm
Storage Temp	Room temperature
Shipped In	Normal
Product Description	Product description 2-Methoxy-4-propylphenol is a volatile phenolic flavor compound identified in Bordeaux wines, liquid smoke, karanda fruit{9 5} and oregano. Product Usage Potential applications include the profile enhancement of smoke flavors, clove, spicy nuances for cinnamon and pepper, vanilla, and fruit nuances.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - Class Phenols
    - Subclass Methoxyphenols

Kingdom	Organic compounds
Superclass	Benzenoids
Class	Phenols
Subclass	Methoxyphenols
Intermediate Tree Nodes	Not available
Direct Parent	Methoxyphenols
Alternative Parents	Phenylpropanes Phenoxy compounds Methoxybenzenes Anisoles Alkyl aryl ethers 1-hydroxy-2-unsubstituted benzenoids Hydrocarbon derivatives
Molecular Framework	Aromatic homomonocyclic compounds
Substituents	Methoxyphenol - Phenylpropane - Phenoxy compound - Methoxybenzene - Phenol ether - Anisole - 1-hydroxy-2-unsubstituted benzenoid - Alkyl aryl ether - Monocyclic benzene moiety - Ether - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Aromatic homomonocyclic compound
Description	This compound belongs to the class of organic compounds known as methoxyphenols. These are compounds containing a methoxy group attached to the benzene ring of a phenol moiety.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

L132 (227 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Aspergillus fumigatus (16427 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	488182409
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488182409
IUPAC Name	2-methoxy-4-propylphenol
INCHI	InChI=1S/C10H14O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h5-7,11H,3-4H2,1-2H3
InChIKey	PXIKRTCSSLJURC-UHFFFAOYSA-N
Smiles	CCCC1=CC(=C(C=C1)O)OC
Isomeric SMILES	CCCC1=CC(=C(C=C1)O)OC
Molecular Weight	166.22
Reaxy-Rn	1866292
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1866292&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

11 results found

Lot Number	Certificate Type	Date	Item
G2220926	Certificate of Analysis	May 07, 2025	M192495
G2220925	Certificate of Analysis	May 07, 2025	M192495
G2220928	Certificate of Analysis	May 07, 2025	M192495
A2224284	Certificate of Analysis	Nov 06, 2024	M192495
A2224285	Certificate of Analysis	Nov 06, 2024	M192495
A2224281	Certificate of Analysis	Nov 06, 2024	M192495
G2130202	Certificate of Analysis	May 14, 2024	M192495
G2130204	Certificate of Analysis	May 14, 2024	M192495
F2419083	Certificate of Analysis	Jun 11, 2022	M192495
D2526022	Certificate of Analysis	Jun 11, 2022	M192495
B2313054	Certificate of Analysis	Jun 11, 2022	M192495

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Chemical and Physical Properties

Refractive Index	n20/D 1.522 (lit.)
Boil Point(°C)	125-126 °C/14 mmHg (lit.)
Molecular Weight	166.220 g/mol
XLogP3	2.200
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	3
Exact Mass	166.099 Da
Monoisotopic Mass	166.099 Da
Topological Polar Surface Area	29.500 Å²
Heavy Atom Count	12
Formal Charge	0
Complexity	125.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Haoquan Guo, Xinyu Lu, Yue Yang, Jinhe Wei, Lizhi Wu, Li Tan, Yu Tang, Xiaoli Gu. (2023) Harvesting alkyl phenols from lignin monomers via selective hydrodeoxygenation under ambient pressure on Pd/α-MoC catalysts. Molecular Catalysis, 540 (113041).
2. Baoyu Wang, Peng Zhou, Ximing Yan, Hu Li, Hongguo Wu, Zehui Zhang. (2023) Cooperative catalysis of Co single atoms and nanoparticles enables selective CAr−OCH3 cleavage for sustainable production of lignin-based cyclohexanols. Journal of Energy Chemistry, 79 (535).
3. Tao Liu, Zhipeng Tian, Weijie Zhang, Bowen Luo, Libin Lei, Chao Wang, Jianping Liu, Riyang Shu, Ying Chen. (2023) Selective hydrodeoxygenation of lignin-derived phenols to alkyl cyclohexanols over highly dispersed RuFe bimetallic catalysts. FUEL, 339 (126916).
4. Dongpo He, Jingyu Xu, Yanzhu Guo, Mengtian Yu, Qingyu Wang, Jinghui Zhou, Xing Wang. (2022) RuNi nanoparticles embedded in N-doped carbon nanofibers as a bimetallic catalyst for the hydrogenolysis of peanut shell lignin. FUEL PROCESSING TECHNOLOGY, 238 (107519).
5. Mingxing Zhao, Jun Hu, Ping Lu, Shiliang Wu, Chao Liu, Yahui Sun. (2022) Efficient hydrodeoxygenation of lignin-derived bio-oil to hydrocarbon fuels over bifunctional RuCoWx/NC catalysts. FUEL, 326 (125020).
6. Huiyuan Wang, Tan Li, Jing Su, Kai Miao, Kaige Wang. (2022) Noncatalytic hydropyrolysis of lignin in a high pressure micro-pyrolyzer. FUEL PROCESSING TECHNOLOGY, 233 (107289).
7. Xiaotong Xu, Jing Kang, Jimin Shen, Shengxin Zhao, Binyuan Wang, Pengwei Yan, Qinglong Fu, Zhonglin Chen. (2022) Formation pathway of disinfection by-products of lignin monomers in raw water during disinfection. SCIENCE OF THE TOTAL ENVIRONMENT, 825 (153706).
8. Genqiang Chen, Lina Zhu, Jiaxuan He, Song Zhang, Yuanhao Li, Xiaolong Guo, Di Sun, Yuee Tian, Shengming Liu, Xiaobo Huang, Zhiping Che. (2021) Synthesis and Anti-Oomycete Activity of 1-Sulfonyloxy/Acyloxydihydroeugenol Derivatives. CHEMISTRY & BIODIVERSITY, 18 (9): (e2100329).
9. Ma Yufeng, Kou Zhimin, Jia Puyou, Zhou Jing. (2021) Effect of benzene ring and alkane chain contained bio-based plasticizers on the plasticizing performance of polyvinyl chloride films. CHEMICAL PAPERS, 75 (10): (5515-5521).
10. Jindong Wang, Wenzhi Li, Huizhen Wang, Ajibola Temitope Ogunbiyi, Xiaomeng Dou, Qiaozhi Ma. (2020) Effects of the novel catalyst Ni–S2O82−–K2O/TiO2 on efficient lignin depolymerization. RSC Advances, 10 (14): (8558-8567).
11. Xiaohao Liu, Chenguang Wang, Ying Zhang, Yan Qiao, Yang Pan, Longlong Ma. (2019) Selective Preparation of 4-Alkylphenol from Lignin-Derived Phenols and Raw Biomass over Magnetic Co–Fe@N-Doped Carbon Catalysts. ChemSusChem, 12 (21): (4791-4798).
12. Lisha Zhao, Xinping Ouyang, Guanfeng Ma, Yong Qian, Xueqing Qiu, Tao Ruan. (2018) Improving antioxidant activity of lignin by hydrogenolysis. INDUSTRIAL CROPS AND PRODUCTS, 125 (228).
13. Zhihao Li, Zhihao Bi, Lifeng Yan. (2017) Two-step hydrogen transfer catalysis conversion of lignin to valuable small molecular compounds. Green Processing and Synthesis, 6 (4): (363-370).
14. Xiaopeng Shi, Haotong Lin, Qi Ouyang, guanqun luo, Xianghong Lu, Jianbing Ji, Kaige Wang. (2025) Biochemical to enable Biorefinery: A case study of polyphenols extraction from Bio-oil for Utilization as Biodiesel Antioxidants. GREEN CHEMISTRY,
15. Shutian Chen, Yating Jian, Yaowei Liu, Zhanying Zhang, Xinlong Li, Qiang Yu. (2024) Deep eutectic solvents promote in-situ hydrogenolysis of Evodia lepta residue in preparing small aromatic phenol ketones. FUEL, 366 (131348).
16. Haoquan Guo, Jiwu Zhao, Yu Chen, Xinyu Lu, Yue Yang, Chenrong Ding, Lizhi Wu, Li Tan, Jinlin Long, Guohui Yang, Yu Tang, Noritatsu Tsubaki, Xiaoli Gu. (2024) Mechanistic Insights into Hydrodeoxygenation of Lignin Derivatives over Ni Single Atoms Supported on Mo2C. ACS Catalysis, 14 (2): (703-717).
17. Kai Dong, Di Zhao, Yang Pang, Binghui Liu, Qian Liu, Tong Mu, Chengji Zhao. (2025) Multiple-reprocessable guaiacol-derived epoxy vitrimer with disulfide crosslinks and closed-loop recycling of carbon fiber-reinforced composites. CHEMICAL ENGINEERING JOURNAL, 508 (160754).
18. Zong-Pin Fu, Qi-Jie Zhou, Yun-Peng Zhao, Yu-Fa Wu, Fang-Jing Liu, Mei Zhong, Jian Li, Jing Liang, Jing-Pei Cao. (2025) Selective hydrodeoxygenation of guaiacol and bio-oil to cycloalkanes over Ni-based catalysts supported on altered Hβ zeolite. Molecular Catalysis, 576 (114932).
19. Ying Wu, Meng Guo, Jie Gao, Jian-Hui Li, Bo-Kun Chen. (2024) Sustainable design and synthesis of high-performance lignin-based sunscreen ingredients. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 280 (135494).
20. Yanyan Yu, Yilin Li, Yuhan Lou, Mengyuan Chen, Yongzhuang Liu, Haipeng Yu. (2025) Tunable Transfer-Hydrodeoxygenated Upgrading of Lignin-Derived Propylphenols to Versatile Value-Added Alkane-Based Chemicals. Advanced Science, (2500687).
21. Xia Zhang, Wenzhi Li, Yihang Jiang, Leyu Zhu, Liqun Wang. (2024) Valorization of waste lignin: Efficient and steady production of liquid fuels. INDUSTRIAL CROPS AND PRODUCTS, 220 (119400).
22. Xiaohong Ren, Qian Qiang, Zhuohua Sun, Ting Wei, Xiaoqiang Yu, Zeming Rong, Changzhi Li. (2024) Water Splitting Integrated with Self-Transfer Hydrogenolysis for Efficient Demethoxylation of Guaiacols to Phenols over the Ni/MgO Catalyst. ACS Catalysis, 14 (7): (5247-5259).

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SKU	Size	Availability	Price
M192495-5g	5g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$9.90
M192495-25g	25g	3	$22.90
M192495-100g	100g	5	$67.90
M192495-500g	500g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$305.90

2-Methoxy-4-(1-propyl)phenol - 98%, high purity , CAS No.2785-87-7