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Basic Description
| Synonyms | 2-HYDROXYPYRIDINE | Pyridin-2-ol | 142-08-5 | 2-Pyridone | 2-Pyridinol | 72762-00-6 | pyridin-2(1H)-one | 2(1H)-Pyridinone | 1H-pyridin-2-one | 2-Pyridinone | 2(1H)-Pyridone | Pyridinone | alpha-Pyridone | 2-Oxopyridine | pyridin-2-one | Pyridone-2 | 2-hydroxy pyridine | .alpha.-Pyridone | |
|---|---|
| Specifications & Purity | 10mM in DMSO |
| Storage Temp | Store at -80°C |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
Taxonomic Classification
Taxonomy Tree
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Kingdom
Organic compounds
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Superclass
Organoheterocyclic compounds
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Class
Pyridines and derivatives
- Subclass Hydropyridines
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Class
Pyridines and derivatives
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Superclass
Organoheterocyclic compounds
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Class | Pyridines and derivatives |
| Subclass | Hydropyridines |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Pyridinones |
| Alternative Parents | Dihydropyridines Heteroaromatic compounds Lactams Azacyclic compounds Organopnictogen compounds Organooxygen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteromonocyclic compounds |
| Substituents | Pyridinone - Dihydropyridine - Heteroaromatic compound - Lactam - Azacycle - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Aromatic heteromonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as pyridinones. These are compounds containing a pyridine ring, which bears a ketone. |
| External Descriptors | a small molecule |
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Associated Targets(Human)
MIA PaCa-2 (5949 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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FKBP5
Tchem
Peptidyl-prolyl cis-trans isomerase FKBP5 (259 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Associated Targets(non-human)
Mmp9
Matrix metalloproteinase 9 (38 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Names and Identifiers
| IUPAC Name | 1H-pyridin-2-one |
|---|---|
| INCHI | InChI=1S/C5H5NO/c7-5-3-1-2-4-6-5/h1-4H,(H,6,7) |
| InChIKey | UBQKCCHYAOITMY-UHFFFAOYSA-N |
| Smiles | C1=CC(=O)NC=C1 |
| Isomeric SMILES | C1=CC(=O)NC=C1 |
| WGK Germany | 3 |
| RTECS | UV1144050 |
| Alternate CAS | 72762-00-6 |
| Molecular Weight | 95.1 |
| Beilstein | 105757 |
| Reaxy-Rn | 105757 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=105757&ln= |
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
| Sensitivity | Light sensitive. |
|---|---|
| Flash Point(°C) | 210°C |
| Boil Point(°C) | 280-281°C |
| Melt Point(°C) | 106-107°C |
| Molecular Weight | 95.100 g/mol |
| XLogP3 | -0.600 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 0 |
| Exact Mass | 95.0371 Da |
| Monoisotopic Mass | 95.0371 Da |
| Topological Polar Surface Area | 29.100 Ų |
| Heavy Atom Count | 7 |
| Formal Charge | 0 |
| Complexity | 135.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
Citations of This Product
| 1. Zengchao Guo, Jiang Xiao, Weiwei Liu, Yihan Wang, Tengfei Liu, Hui Jiang, Xiaohui Liu, Xuemei Wang. (2023) Cationic porphyrin-based nanoparticles assisted with bio-assembly imaging-guided strategy for efficient inactivation of bacteria and promote wound healing. CHEMICAL ENGINEERING JOURNAL, 457 (141218). |
| 2. Yi Xiao, Haomin Yi, Jingzhi Zhu, Suhua Chen, Guofang Wang, Yilong Liao, Yuanyuan Lei, Liyin Chen, Xingcai Zhang, Fangfu Ye. (2023) Evaluation of DNA adduct damage using G-quadruplex-based DNAzyme. Bioactive Materials, 23 (45). |
| 3. Yang Dan, Mei Shiliang, Wen Zhuoqi, Wei Xian, Cui Zhongjie, Yang Bobo, Wei Chang, Qiu Yi, Li Min, Li Hui, Zhang Wanlu, Xie Fengxian, Wang Le, Guo Ruiqian. (2020) Dual-emission of silicon nanoparticles encapsulated lanthanide-based metal-organic frameworks for ratiometric fluorescence detection of bacterial spores. MICROCHIMICA ACTA, 187 (12): (1-9). |
| 4. Lei Yuan, Hongshuai Gao, Haiyan Jiang, Shaojuan Zeng, Tao Li, Baozeng Ren, Xiangping Zhang. (2021) Experimental and thermodynamic analysis of NH3 absorption in dual-functionalized pyridinium-based ionic liquids. JOURNAL OF MOLECULAR LIQUIDS, 323 (114601). |
| 5. Cui-Ping Ye, Rui-Nan Wang, Xia Gao, Wen-Ying Li. (2020) CO2 Capture Performance of Supported Phosphonium Dual Amine-Functionalized Ionic Liquids@MCM-41. ENERGY & FUELS, 34 (11): (14379–14387). |
| 6. Li Xin, Lu Chao, Xia Wenquan, Quan Guilan, Huang Ying, Bai Xuequn, Yu Feiyuan, Xu Qian, Qin Wanbing, Liu Daojun, Pan Xin. (2020) Poly(L-Glutamic Acid)-Based Brush Copolymers: Fabrication, Self-assembly, and Evaluation as Efficient Nanocarriers for Cationic Protein Drug Delivery. AAPS PHARMSCITECH, 21 (3): (1-10). |
| 7. Zhao Shuxue, Hu Chunhui, Guo Lizhong, Li Kuiran, Yu Hao. (2019) Isolation of a 3-hydroxypyridine degrading bacterium, Agrobacterium sp. DW-1, and its proposed degradation pathway. AMB Express, 9 (1): (1-9). |
| 8. Xiao-Yan Luo, Xiao-Yan Chen, Rong-Xing Qiu, Bao-You Pei, Yi Wei, Min Hu, Jin-Qing Lin, Jing-Yang Zhang, Geng-Geng Luo. (2019) Enhanced CO2 capture by reducing cation–anion interactions in hydroxyl-pyridine anion-based ionic liquids. DALTON TRANSACTIONS, 48 (7): (2300-2307). |
| 9. Fei Tong, Xiangyuan Tang, Xin Li, Wenquan Xia, Daojun Liu. (2016) The effect of insulin-loaded linear poly(ethylene glycol)-brush-like poly(l-lysine) block copolymer on renal ischemia/reperfusion-induced lung injury through downregulating hypoxia-inducible factor. International Journal of Nanomedicine, |
| 10. Ying Chen, Lei Tian, Wen Liu, Yi Mei, Qiu-Ju Xing, Yi Mu, Ling-Ling Zheng, Qian Fu, Jian-Ping Zou, Daishe Wu. (2024) Controllable Pyridine N-Oxidation–Nucleophilic Dechlorination Process for Enhanced Dechlorination of Chloropyridines: The Cooperation of HCO4– and HO2–. ENVIRONMENTAL SCIENCE & TECHNOLOGY, 58 (9): (4438-4449). |
| 11. Zhaoyang Qi, Shiquan Zhong, Huiyun Su, Changshen Ye, Limei Ren, Ting Qiu, Jie Chen. (2024) Tuning the cross-linked structure of basic poly(ionic liquid) to develop an efficient catalyst for the conversion of vinyl carbonate to dimethyl carbonate. CHINESE JOURNAL OF CHEMICAL ENGINEERING, 72 (106). |
| 12. Xiao Zhu, Shuhui Liu, Ruhui Shang, Xin Chen, Yingjie Xu, Yujun Guo, Baoping Ling. (2024) Understanding on the structure of novel hydroxypyridine anion-based ionic liquids and their effect on CO2 absorption behavior. Journal of Environmental Chemical Engineering, 12 (113552). |
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