Basic Description

Synonyms	2-(Hydroxymethyl)-1,2-crown 4-ether \| (1,4,7,10-Tetraoxacyclododecan-2-yl)methanol \| 1,4,7,10-Tetraoxacyclododecan-2-methanol \| 1,4,7,10-tetraoxacyclododec-2-ylmethanol \| NJIPEIQHUNDGPY-UHFFFAOYSA-N \| 2-Hydroxymethyl-12-crown-4, 95% \| 2-(Hydroxymethyl)-12
Specifications & Purity	≥95%(GC)
Storage Temp	Protected from light,Argon charged
Shipped In	Normal
Product Description	2-Hydroxymethyl-12-crown-4 can be used: To prepare an ester of lasalocid with crown ether to study its complex formation with monovalent cations. To prepare hydrogel adsorbents for potential usage in the recovery of lithium-ions from seawater. As a starting material in the synthesis of metal-free phthalocyanines and metallophthalocyanines.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic oxygen compounds
  - Class Organooxygen compounds
    - Subclass Ethers

Kingdom	Organic compounds
Superclass	Organic oxygen compounds
Class	Organooxygen compounds
Subclass	Ethers
Intermediate Tree Nodes	Not available
Direct Parent	Dialkyl ethers
Alternative Parents	Oxacyclic compounds Primary alcohols Hydrocarbon derivatives
Molecular Framework	Aliphatic heteromonocyclic compounds
Substituents	Oxacycle - Organoheterocyclic compound - Dialkyl ether - Hydrocarbon derivative - Primary alcohol - Alcohol - Aliphatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as dialkyl ethers. These are organic compounds containing the dialkyl ether functional group, with the formula ROR', where R and R' are alkyl groups.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

Pubchem Sid	488192354
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488192354
IUPAC Name	1,4,7,10-tetraoxacyclododec-2-ylmethanol
INCHI	InChI=1S/C9H18O5/c10-7-9-8-13-4-3-11-1-2-12-5-6-14-9/h9-10H,1-8H2
InChIKey	NJIPEIQHUNDGPY-UHFFFAOYSA-N
Smiles	C1COCCOC(COCCO1)CO
Isomeric SMILES	C1COCCOC(COCCO1)CO
WGK Germany	3
Molecular Weight	206.24
Beilstein	4661970
Reaxy-Rn	4661968
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4661968&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot Number	Certificate Type	Date	Item
F2424258	Certificate of Analysis	May 28, 2024	H157004
F2302496	Certificate of Analysis	May 05, 2023	H157004
F2303294	Certificate of Analysis	May 05, 2023	H157004
K2224510	Certificate of Analysis	Nov 11, 2022	H157004
K2224511	Certificate of Analysis	Nov 11, 2022	H157004

Chemical and Physical Properties

Solubility	Miscible in water. Soluble in non-polar solvents. Insoluble in water.
Sensitivity	Light sensitive；air sensitive
Refractive Index	n20/D 1.480
Flash Point(°F)	235.4 °F
Flash Point(°C)	113 °C
Boil Point(°C)	115 °C/0.04 mmHg
Molecular Weight	206.240 g/mol
XLogP3	-1.200
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	1
Exact Mass	206.115 Da
Monoisotopic Mass	206.115 Da
Topological Polar Surface Area	57.200 Å²
Heavy Atom Count	14
Formal Charge	0
Complexity	130.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Weiwei Kang, Hong Zhao, Yan Cui, Xuguang Liu, Yongzhen Yang. (2024) Construction of novel stable surface ion-imprinted graphene aerogels for efficient and selective extraction of lithium ion. SEPARATION AND PURIFICATION TECHNOLOGY, 333 (125946).
2. Weifeng Liu, Guang Yan, Erhui Zhang, Qi Liang, Lei Qin, Meiling Wang, Xuguang Liu, Yongzhen Yang. (2020) Extraction of lithium ions from acidic solution using electrochemically imprinted membrane. DESALINATION, 496 (114751).
3. Yan Cui, Wenrui Du, Hong Zhao, Weiwei Kang, Xuguang Liu, Yongzhen Yang. (2025) A novel recyclable surface ion-imprinted graphene aerogels for high selective adsorption of lithium in salt lake brine. Surfaces and Interfaces, 56 (105574).

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2-(Hydroxymethyl)-12-crown 4-Ether - >95.0%(GC), high purity , CAS No.75507-26-5