Basic Description

Synonyms	chloronicotinamide \| BCP23241 \| 3-Pyridinecarboxamide, 2-chloro- \| AKOS000121160 \| EN300-26649 \| EINECS 233-808-9 \| A23892 \| AM20050624 \| Z33546502 \| 2-Chloronicotinamide \| 2-chloro-nicotinamide \| FT-0611978 \| 2-Chloronicotinamide, 98% \| InChI=1/C6H5ClN2O
Specifications & Purity	≥98%
Shipped In	Normal
Product Description	2-Chloronicotinamide was used in the synthesis of pyrrolopyridines and thiol ester derived from 2-mecaptonicotinamide.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Pyridines and derivatives
    - Subclass Pyridinecarboxylic acids and derivatives
      - Level5 Pyridinecarboxamides
        Level6 Nicotinamides

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Pyridines and derivatives
Subclass	Pyridinecarboxylic acids and derivatives
Intermediate Tree Nodes	Pyridinecarboxamides
Direct Parent	Nicotinamides
Alternative Parents	2-halopyridines Aryl chlorides Vinylogous halides Heteroaromatic compounds Primary carboxylic acid amides Azacyclic compounds Organopnictogen compounds Organooxygen compounds Organonitrogen compounds Organochlorides Organic oxides Hydrocarbon derivatives
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	Nicotinamide - 2-halopyridine - Aryl chloride - Aryl halide - Vinylogous halide - Heteroaromatic compound - Carboxamide group - Primary carboxylic acid amide - Carboxylic acid derivative - Azacycle - Organic oxide - Organic nitrogen compound - Organooxygen compound - Organonitrogen compound - Organochloride - Organohalogen compound - Organopnictogen compound - Organic oxygen compound - Hydrocarbon derivative - Aromatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as nicotinamides. These are heterocyclic aromatic compounds containing a pyridine ring substituted at position 3 by a carboxamide group.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

Pubchem Sid	488186108
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488186108
IUPAC Name	2-chloropyridine-3-carboxamide
INCHI	InChI=1S/C6H5ClN2O/c7-5-4(6(8)10)2-1-3-9-5/h1-3H,(H2,8,10)
InChIKey	ZQZAHPFFZWEUCL-UHFFFAOYSA-N
Smiles	C1=CC(=C(N=C1)Cl)C(=O)N
Isomeric SMILES	C1=CC(=C(N=C1)Cl)C(=O)N
WGK Germany	3
Molecular Weight	156.57
Beilstein	22(2)36
Reaxy-Rn	119026
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=119026&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot Number	Certificate Type	Date	Item
H1723042	Certificate of Analysis	Mar 04, 2025	C154057
F2406168	Certificate of Analysis	Mar 23, 2024	C154057
F2406169	Certificate of Analysis	Mar 23, 2024	C154057
D2001182	Certificate of Analysis	Jan 04, 2024	C154057
F2310680	Certificate of Analysis	Dec 13, 2021	C154057

Chemical and Physical Properties

Melt Point(°C)	164-167°C
Molecular Weight	156.570 g/mol
XLogP3	1.600
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	1
Exact Mass	156.009 Da
Monoisotopic Mass	156.009 Da
Topological Polar Surface Area	56.000 Å²
Heavy Atom Count	10
Formal Charge	0
Complexity	140.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Zhe-Ming Wu, Feng Xie, Wen Zheng, Chang-Feng Liu, Chao-Ping Lin, Ren-Chao Zheng, Yu-Guo Zheng. (2023) Structure-Oriented Engineering of Amidase: Modification of Twisted Access Tunnel for Efficient Synthesis of 2-Chloronicotinic Acid. ACS Catalysis, 13 (13): (9078–9089).
2. Ren-Chao Zheng, Jian-Qiang Jin, Zhe-Ming Wu, Xiao-Ling Tang, Li-Qun Jin, Yu-Guo Zheng. (2018) Biocatalytic hydrolysis of chlorinated nicotinamides by a superior AS family amidase and its application in enzymatic production of 2-chloronicotinic acid. BIOORGANIC CHEMISTRY, 76 (81).

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SKU	Size	Availability	Price
C154057-1g	1g	10	$10.90
C154057-5g	5g	6	$40.90
C154057-25g	25g	5	$137.90
C154057-100g	100g	5	$495.90
C154057-500g	500g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$2,231.90

2-Chloronicotinamide - >98.0%, high purity , CAS No.10366-35-5