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2-Chloro-4-cyanopyridine - 97%, high purity , CAS No.33252-30-1

COA

Grade & Purity:

≥97%

Cas Number: 33252-30-1
Molecular Weight: 138.55
Beilstein Registry Number: 22(5)2,302
MDL number: MFCD00174318
PubChem CID: 568638
PubChem SID: 488190347

In stock

Item Number

C107767

Grouped product items
SKU	Size	Availability	Price
C107767-5g	5g	3	$42.90
C107767-25g	25g	8	$192.90
C107767-100g	100g	3	$692.90
C107767-250g	250g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$1,558.90
C107767-500g	500g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,804.90

View related series

Chloropyridine (241) Halogenated heterocyclic block (1171)

Basic Description

Synonyms	2-chloro-4 pyridinecarbonitrile \| MFCD00174318 \| Pyridine, 2-chloro-, 4-cyano- \| BCP9000101 \| Isonicotinonitrile, 2-chloro- \| 2-Chloro-4-cyanopyridine \| 2-chloro-4-cyano-pyridine \| 4-cyano-2-chloropyridin \| AB04394 \| 4-Pyridinecarbonitrile, 2-chloro- \| UN
Specifications & Purity	≥97%
Shipped In	Normal
Product Description	2-Chloro-4-cyanopyridine is an intermediate used to prepare pyrrolopyridine inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2). It is also used to synthesize pyridinyl-tetrazoles as scaffold to identify matrix MMP-13 inhibitors for treatment of osteoarthritis.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Pyridines and derivatives
    - Subclass Halopyridines

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Pyridines and derivatives
Subclass	Halopyridines
Intermediate Tree Nodes	Not available
Direct Parent	2-halopyridines
Alternative Parents	Aryl chlorides Heteroaromatic compounds Nitriles Azacyclic compounds Organopnictogen compounds Organochlorides Hydrocarbon derivatives
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	2-halopyridine - Aryl halide - Aryl chloride - Heteroaromatic compound - Azacycle - Nitrile - Carbonitrile - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Organochloride - Organohalogen compound - Aromatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as 2-halopyridines. These are organic compounds containing a pyridine ring substituted at the 2-position by a halogen atom.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

Pubchem Sid	488190347
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488190347
IUPAC Name	2-chloropyridine-4-carbonitrile
INCHI	InChI=1S/C6H3ClN2/c7-6-3-5(4-8)1-2-9-6/h1-3H
InChIKey	QRXBTPFMCTXCRD-UHFFFAOYSA-N
Smiles	C1=CN=C(C=C1C#N)Cl
Isomeric SMILES	C1=CN=C(C=C1C#N)Cl
WGK Germany	3
Molecular Weight	138.55
Beilstein	22(5)2,302
Reaxy-Rn	113927
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=113927&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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7 results found

Lot Number	Certificate Type	Date	Item
H2209199	Certificate of Analysis	May 12, 2025	C107767
H2209212	Certificate of Analysis	May 12, 2025	C107767
H2209219	Certificate of Analysis	May 12, 2025	C107767
G1919067	Certificate of Analysis	Mar 04, 2025	C107767
K2111508	Certificate of Analysis	Aug 21, 2024	C107767
K2111509	Certificate of Analysis	Aug 21, 2024	C107767
K2111542	Certificate of Analysis	Aug 21, 2024	C107767

Chemical and Physical Properties

Solubility	soluble in MeOH
Boil Point(°C)	106°C/15mmHg
Melt Point(°C)	72°C
Molecular Weight	138.550 g/mol
XLogP3	1.500
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	0
Exact Mass	137.998 Da
Monoisotopic Mass	137.998 Da
Topological Polar Surface Area	36.700 Å²
Heavy Atom Count	9
Formal Charge	0
Complexity	137.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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