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2-Amino-N-quinolin-8-yl-benzenesulfonamide - 98%, high purity , CAS No.16082-64-7

COA

Grade & Purity:

≥98%

Cas Number: 16082-64-7
Molecular Weight: 299.35
PubChem CID: 1070159
PubChem SID: 488191708

In stock

Item Number

A338659

Grouped product items
SKU	Size	Availability	Price
A338659-5mg	5mg	3	$190.90
A338659-25mg	25mg	2	$859.90
A338659-100mg	100mg	1	$3,093.90
A338659-250mg	250mg	1	$6,960.90

an apoptosis inducer that inhibits cell cycle at G2 phase

View related series

Apoptosis (4276)

Basic Description

Synonyms	CU-00000000193-2 \| AB00074880-01 \| D92911 \| Oprea1_584159 \| 2-amino-N-(quinolin-8-yl)benzenesulfonamide \| NCGC00161683-04 \| HY-115683 \| CBDivE_007127 \| AKOS000154013 \| NCGC00161683-03 \| DTXSID90360049 \| NUN-82647; NUN 82647;QBS;2-Amino-N-quinolin-8-yl-ben
Specifications & Purity	≥98%
Storage Temp	Room temperature
Shipped In	Normal

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - Class Benzene and substituted derivatives
    - Subclass Benzenesulfonamides

Kingdom	Organic compounds
Superclass	Benzenoids
Class	Benzene and substituted derivatives
Subclass	Benzenesulfonamides
Intermediate Tree Nodes	Not available
Direct Parent	Aminobenzenesulfonamides
Alternative Parents	Sulfanilides Quinolines and derivatives Benzenesulfonyl compounds Aniline and substituted anilines Pyridines and derivatives Organosulfonamides Heteroaromatic compounds Aminosulfonyl compounds Azacyclic compounds Primary amines Organopnictogen compounds Organic oxides Hydrocarbon derivatives
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Aminobenzenesulfonamide - Quinoline - Sulfanilide - Benzenesulfonyl group - Aniline or substituted anilines - Pyridine - Organosulfonic acid amide - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Sulfonyl - Aminosulfonyl compound - Heteroaromatic compound - Organoheterocyclic compound - Azacycle - Hydrocarbon derivative - Organic nitrogen compound - Amine - Organic oxide - Organopnictogen compound - Organic oxygen compound - Primary amine - Organonitrogen compound - Organosulfur compound - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as aminobenzenesulfonamides. These are organic compounds containing a benzenesulfonamide moiety with an amine group attached to the benzene ring.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

NFKBIA Tchem NF-kappaB inhibitor alpha (187 Activities)

Discover Target: NFKBIA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RELA Tchem Nuclear factor NF-kappa-B p65 subunit (627 Activities)

Discover Target: RELA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)

Discover Target: KDM4A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)

Discover Target: APEX1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

Discover Target: TDP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MEN1 Tchem Menin/Histone-lysine N-methyltransferase MLL (48157 Activities)

Discover Target: MEN1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Trypanosoma brucei brucei (13300 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

Discover Target: Nfe2l2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rorc Nuclear receptor ROR-gamma (89407 Activities)

Discover Target: Rorc

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

fba Putative fructose-1,6-bisphosphate aldolase (15559 Activities)

Discover Target: fba

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

FTL Ferritin light chain (43324 Activities)

Discover Target: FTL

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	488191708
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488191708
IUPAC Name	2-amino-N-quinolin-8-ylbenzenesulfonamide
INCHI	InChI=1S/C15H13N3O2S/c16-12-7-1-2-9-14(12)21(19,20)18-13-8-3-5-11-6-4-10-17-15(11)13/h1-10,18H,16H2
InChIKey	NIOOKXAMJQVDGB-UHFFFAOYSA-N
Smiles	C1=CC=C(C(=C1)N)S(=O)(=O)NC2=CC=CC3=C2N=CC=C3
Isomeric SMILES	C1=CC=C(C(=C1)N)S(=O)(=O)NC2=CC=CC3=C2N=CC=C3
WGK Germany	3
Molecular Weight	299.35
Reaxy-Rn	426058
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=426058&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

12 results found

Lot Number	Certificate Type	Date	Item
H2305164	Certificate of Analysis	Jul 25, 2023	A338659
H2305163	Certificate of Analysis	Jul 25, 2023	A338659
H2305153	Certificate of Analysis	Jul 25, 2023	A338659
H2305149	Certificate of Analysis	Jul 25, 2023	A338659
H2305143	Certificate of Analysis	Jul 25, 2023	A338659
H2305155	Certificate of Analysis	Jul 25, 2023	A338659
H2305159	Certificate of Analysis	Jul 25, 2023	A338659
H2305148	Certificate of Analysis	Jul 25, 2023	A338659
H2305162	Certificate of Analysis	Jul 25, 2023	A338659
H2305152	Certificate of Analysis	Jul 25, 2023	A338659
H2305156	Certificate of Analysis	Jul 25, 2023	A338659
H2305158	Certificate of Analysis	Jul 25, 2023	A338659

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Chemical and Physical Properties

Solubility	Soluble in DMSO: 22 mg/mL
Molecular Weight	299.300 g/mol
XLogP3	1.600
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	3
Exact Mass	299.073 Da
Monoisotopic Mass	299.073 Da
Topological Polar Surface Area	93.500 Å²
Heavy Atom Count	21
Formal Charge	0
Complexity	448.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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