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2-Amino-9H-pyrido[2-3-b]indole - 98%, high purity , CAS No.26148-68-5
Basic Description
Synonyms
HSDB 7086 | 2-Amino-a-carboline | BRN 0744369 | CCRIS 38 | AMINO-9H-PYRIDO(2,3-B)INDOLE, 2- | J-016280 | 9H-PYRIDO(2,3-B)INDOL-2-AMINE | FJTNLJLPLJDTRM-UHFFFAOYSA-N | 2-AMINO-9H-PYRIDO(2,3-B)INDOLE [HSDB] | A818215 | Q27155854 | 2-Amino-alpha-carboline;Aa
Specifications & Purity
≥98%
Biochemical and Physiological Mechanisms
AαC (2-Amino-9H-pyrido[2-3-b]indole) is a potential human carcinogen, which is generated by the combustion of tobacco, or by pyrolysis of protein. AαC potentially contributes to liver or digestive tract cancers. Inside body AαC is metabolized to intermedi
Storage Temp
Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Taxonomic Classification
Kingdom
Organic compounds
Superclass
Organoheterocyclic compounds
Class
Indoles and derivatives
Subclass
Pyridoindoles
Intermediate Tree Nodes
Not available
Direct Parent
Alpha carbolines
Alternative Parents
Pyrrolopyridines Indoles Pyridines and derivatives Imidolactams Benzenoids Pyrroles Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Hydrocarbon derivatives
Molecular Framework
Aromatic heteropolycyclic compounds
Substituents
Alpha-carboline - Pyrrolopyridine - Indole - Imidolactam - Benzenoid - Pyridine - Heteroaromatic compound - Pyrrole - Azacycle - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Aromatic heteropolycyclic compound
Description
This compound belongs to the class of organic compounds known as alpha carbolines. These are organic compounds containing a pyrido[2,3-b]indole core (which is a pyridine fused to an indole).
External Descriptors
pyridoindole
Data sources
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Associated Targets(Human)
Mechanisms of Action
Mechanism of Action
Action Type
target ID
Target Name
Target Type
Target Organism
Binding Site Name
References
Names and Identifiers
IUPAC Name
9H-pyrido[2,3-b]indol-2-amine
INCHI
InChI=1S/C11H9N3/c12-10-6-5-8-7-3-1-2-4-9(7)13-11(8)14-10/h1-6H,(H3,12,13,14)
InChIKey
FJTNLJLPLJDTRM-UHFFFAOYSA-N
Smiles
C1=CC=C2C(=C1)C3=C(N2)N=C(C=C3)N
Isomeric SMILES
C1=CC=C2C(=C1)C3=C(N2)N=C(C=C3)N
Molecular Weight
183.21
Reaxy-Rn
744369
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=744369&ln=
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
Chemical and Physical Properties
Sensitivity
Air Sensitive,Heat Sensitive
Boil Point(°C)
441 °C
Melt Point(°C)
201 °C
Molecular Weight
183.210 g/mol
XLogP3
2.600
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
0
Exact Mass
183.08 Da
Monoisotopic Mass
183.08 Da
Topological Polar Surface Area
54.700 Ų
Heavy Atom Count
14
Formal Charge
0
Complexity
219.000
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
The total count of all stereochemical bonds
0
Covalently-Bonded Unit Count
1
Citations of This Product
1.
Peijian Sun, Yipeng Wang, Song Yang, Xuehui Sun, Bin Peng, Lining Pan, Yunzhen Jia, Xiaobing Zhang, Cong Nie.
(2023)
Molecularly Imprinted Polymer Nanospheres with Hydrophilic Shells for Efficient Molecular Recognition of Heterocyclic Aromatic Amines in Aqueous Solution. MOLECULES,
28
(5):
(2052).
2.
Xiaohan Zang, Yongcheng Wang, Cong Han, Lishuang Cui, Haojie Liu, Shuimiao Tian, Kechun Liu, Peihai Li, Chen Sun, Qing Xia, Yun Zhang.
(2024)
2-Acetamidophenol (2-AAP) Suppresses the Progression of Atherosclerosis by Alleviating Hyperlipidemia and Attenuating the Ferroptosis Pathway. Marine Drugs,
22
(11):
(513).
3.
Junhao Cui, Zhiyang Zhao, Yongqi Ren, Bailong Chen, Chase Rheinlander, Antonio Xavier Moore, Longzhi Li.
(2024)
Excellent cycle stability of Fe loaded on N-doped activated carbon for microwave hydrogenolysis of lignin. CHEMICAL ENGINEERING JOURNAL,
502
(158001).
4.
Hina Ramzan, Faiqa Nadeem, Muhammad Usman, Muhammad Shahzaib, Muneeb Ur Rahman, Fuhua Shen, Zhiping Zhang, Reeta Rani Singhania, Farzana Jabeen, Waheed Afzal, Nadeem Tahir.
(2024)
Investigating the quantum size effects of multi-walled carbon nanotubes (MWCNTs) in photocatalytic fermentative biohydrogen production. Journal of Cleaner Production,
(141738).
5.
Xiaobo Li, Kaifeng Yang, Fangming Han, Yafeng Jin, Haonan Zhang, Heng Gao.
(2024)
Simultaneous and sensitive detection of dopamine and acetaminophen at a glassy carbon electrode modified with a carbonized-ZIF-67/Super P nanocomposite. NEW JOURNAL OF CHEMISTRY,
48
(7):
(3294-3303).
6.
Jie Kang, Jiangyi Di, Hao Zhang, Yuting Hao, Yongqin Guo, Zixin Tian, Shuang Zhao.
(2024)
Simultaneous voltammetric detection of acetaminophen and levofloxacin based on barley leaves derived carbon decorated with gold nanoparticles. MICROCHEMICAL JOURNAL,
205
(111335).
7.
Yu-Ting Cao, Shuai-Wei Lu, Yu-hang Zhou, Jun Wei.
(2024)
The synthesis and research of a novel organosilicon-modified waterborne blocked polyisocyanate crosslinker with a semi-interpenetrating network structure. PROGRESS IN ORGANIC COATINGS,
190
(108413).
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7 Citations
J2310021