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2-Amino-4-hydroxy-6-methylpyrimidine - >98.0%(HPLC)(T), high purity , CAS No.3977-29-5

    Grade & Purity:
  • ≥98%(HPLC)(T)
In stock
Item Number
A151322
Grouped product items
SKU Size
Availability
Price Qty
A151322-5g
5g
4
$9.90
A151322-25g
25g
4
$14.90
A151322-50g
50g
3
$25.90
A151322-100g
100g
3
$45.90
A151322-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$195.90

Basic Description

Synonyms 2-Amino-4-hydroxy-6-methylpyrimidine, 98% | 2-Amino-6-hydroxy-4-methylpyrimidine | 2-imino4-hydroxy-6-methylpyrimidine | 6-methyl-2-[(E)-phenyldiazenyl]pyridin-3-ol | EINECS 223-612-1 | KWXIPEYKZKIAKR-UHFFFAOYSA- | NSC-41833 | BBL023362 | AI3-08094 | NSC
Specifications & Purity ≥98%(HPLC)(T)
Shipped In Normal

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organoheterocyclic compounds
Class Diazines
Subclass Pyrimidines and pyrimidine derivatives
Intermediate Tree Nodes Not available
Direct Parent Pyrimidones
Alternative Parents Aminopyrimidines and derivatives  Hydropyrimidines  Vinylogous amides  Heteroaromatic compounds  Azacyclic compounds  Primary amines  Organopnictogen compounds  Organooxygen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular Framework Aromatic heteromonocyclic compounds
Substituents Aminopyrimidine - Pyrimidone - Hydropyrimidine - Vinylogous amide - Heteroaromatic compound - Azacycle - Amine - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Primary amine - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Aromatic heteromonocyclic compound
Description This compound belongs to the class of organic compounds known as pyrimidones. These are compounds that contain a pyrimidine ring, which bears a ketone. Pyrimidine is a 6-membered ring consisting of four carbon atoms and two nitrogen centers at the 1- and 3- ring positions.
External Descriptors hydroxypyrimidine - aminopyrimidine

Associated Targets(Human)

BACE1 Tchem Beta-secretase 1 (15641 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Pseudomonas aeruginosa (123386 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Klebsiella pneumoniae (43867 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Acinetobacter baumannii (41033 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Escherichia coli (133304 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Cryptococcus neoformans (21258 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Candida albicans (78123 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
EAPA Endothiapepsin (23 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

Pubchem Sid 488202837
Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488202837
IUPAC Name 2-amino-4-methyl-1H-pyrimidin-6-one
INCHI InChI=1S/C5H7N3O/c1-3-2-4(9)8-5(6)7-3/h2H,1H3,(H3,6,7,8,9)
InChIKey KWXIPEYKZKIAKR-UHFFFAOYSA-N
Smiles CC1=CC(=O)NC(=N1)N
Isomeric SMILES CC1=CC(=O)NC(=N1)N
WGK Germany 3
Molecular Weight 125.13
Beilstein 25(3/4)3704
Reaxy-Rn 3531
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3531&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

24 results found

Lot Number Certificate Type Date Item
F2116074 Certificate of Analysis Mar 04, 2025 A151322
C2511335 Certificate of Analysis Jun 24, 2024 A151322
C2517762 Certificate of Analysis Jun 24, 2024 A151322
L2216286 Certificate of Analysis Dec 02, 2022 A151322
L2216280 Certificate of Analysis Dec 02, 2022 A151322
L2216255 Certificate of Analysis Dec 02, 2022 A151322
L2216281 Certificate of Analysis Dec 02, 2022 A151322
L2216284 Certificate of Analysis Dec 02, 2022 A151322
L2216283 Certificate of Analysis Dec 02, 2022 A151322
B2508092 Certificate of Analysis Dec 02, 2022 A151322
L2216279 Certificate of Analysis Dec 02, 2022 A151322
L2216282 Certificate of Analysis Dec 02, 2022 A151322
L2216285 Certificate of Analysis Dec 02, 2022 A151322
I2217033 Certificate of Analysis Jul 30, 2022 A151322
I2217035 Certificate of Analysis Jul 30, 2022 A151322
I2217034 Certificate of Analysis Jul 30, 2022 A151322
I2217039 Certificate of Analysis Jul 30, 2022 A151322
C2201258 Certificate of Analysis Jan 17, 2022 A151322
K2229867 Certificate of Analysis Jan 17, 2022 A151322
C2201209 Certificate of Analysis Jan 17, 2022 A151322
C2201222 Certificate of Analysis Jan 17, 2022 A151322
C2201224 Certificate of Analysis Jan 17, 2022 A151322
C2201214 Certificate of Analysis Jan 17, 2022 A151322
B2309366 Certificate of Analysis Sep 14, 2021 A151322

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Chemical and Physical Properties

Solubility Solubility in HCl(1+3):almost transparency
Melt Point(°C) >300°C
Molecular Weight 125.130 g/mol
XLogP3 -0.900
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 2
Rotatable Bond Count 0
Exact Mass 125.059 Da
Monoisotopic Mass 125.059 Da
Topological Polar Surface Area 67.500 Ų
Heavy Atom Count 9
Formal Charge 0
Complexity 204.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

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2. Haiyang Liao, Wenzhao Zhong, Chen Li, Jieling Han, Xiao Sun, Xinhui Xia, Ting Li, Abolhassan Noori, Mir F. Mousavi, Xin Liu, Yongqi Zhang.  (2024)  An intrinsically self-healing and anti-freezing molecular chains induced polyacrylamide-based hydrogel electrolytes for zinc manganese dioxide batteries.  Journal of Energy Chemistry,  89  (565). 
3. Jumin Yang, Xin Jin, Wenguang Liu, Wei Wang.  (2023)  A Programmable Oxygenation Device Facilitates Oxygen Generation and Replenishment to Promote Wound Healing.  ADVANCED MATERIALS,    (2305819). 
4. Yuanyang Xu, Yanjun Wang, Hongxiu Wei, Tiancheng Dai, Zhen Li, Jiehua Li, Feng Luo, Hong Tan.  (2023)  4D printable shape memory polyurethane with quadruple hydrogen bonding assembly.  JOURNAL OF POLYMER SCIENCE,     
5. Qiangwei Xin, Zhengxin Ma, Shiran Sun, Hongbo Zhang, Yan Zhang, Liangrui Zuo, Yifei Yang, Jing Xie, Chunmei Ding, Jianshu Li.  (2023)  Supramolecular Self-Healing Antifouling Coating for Dental Materials.  ACS Applied Materials & Interfaces,     
6. Yuehua Zhao, Hongbo Chen, Shaojie Geng, Shunjie Liu, Dapeng Wang.  (2023)  Emission Properties of Individual AIE-Luminogens in Solution at Room Temperature†.  CHINESE JOURNAL OF CHEMISTRY,  41  (23): (3245-3252). 
7. Yu Yuan, Shihu Zhu, Jun Zhu, Peixin Niu, Ailing Sun, Xingjiang Liu, Liuhe Wei, Yuhan Li.  (2023)  An impact-strengthening, reusable hot-melt structural adhesive derived from branching polyurethane-based supramolecular topology capped by self-complementary hydrogen bonding UPy motifs.  EUROPEAN POLYMER JOURNAL,  196  (112253). 
8. Ruliang Liu, Jiaxin Ou, Lijun Xie, Yubing Liang, Xinyi Lai, Zhaoxia Deng, Wei Yin.  (2023)  Aqueous Supramolecular Binder for High-Performance Lithium–Sulfur Batteries.  Polymers,  15  (12): (2599). 
9. Lin Yu-Cai, Chen Feng, Yang Shou-Bin, Gong Shu-Yue, Luo Yu-Xiang, Wei Fang-Fang, Ding Fu-Chuan, Bai Wei-Bin, Jian Rong-Kun.  (2023)  Mechanical Strong, Highly Adhesive, Recyclable and Transparent Supramolecular Silicone Coatings with Easy Water/Oil Sliding.  CHINESE JOURNAL OF POLYMER SCIENCE,  41  (11): (1796-1804). 
10. Haiyang Liao, Wenzhao Zhong, Jieling Han, Yeqi Xiao, Tieming Xiao, Xiao Sun, Guixin Cui, Jie Huang.  (2023)  Self-healable and freeze-resistant polyelectrolyte based on an EG anchor chain and dual dynamic reversible interaction as highly sensitive ionic skin.  Journal of Materials Chemistry C,  11  (14): (4753-4765). 
11. Xue-Wei Wei, Cong Chen, Tian-Yu Wu, Li-Hai Cai, Hai-Mu Ye.  (2022)  Promoting Co-Crystallization in Poly(butylene succinate) and Poly(butylene fumarate) Blends via End-Group Functionalization.  MOLECULES,  27  (20): (7086). 
12. Wenjing Liu, Xin Zhang, Yujie Qiang, Guangming Lu, Xijian Lan, Bin Chen, Haichao Zhao.  (2022)  Ureidopyrimidinone-containing Poly(amino ester) for corrosion inhibition of mild steel in acidic medium.  MATERIALS CHEMISTRY AND PHYSICS,  292  (126818). 
13. Zhao Sipei, Li Shuiquan, Liu Huihui, Jiang Jin, Wang Meichen, Liu Haolang, Wang Weiwei, Wang Zhi.  (2022)  Quadruple hydrogen bond motif-toughened polybenzoxazine with improved comprehensive performances.  Advanced Composites and Hybrid Materials,  (4): (3057-3067). 
14. Guangfeng Wu, Jiaqi Li, Qing Zhang, huixuan Zhang.  (2022)  Synergistic effect of multiple hydrogen bond and disulfide bond on healing waterborne conductive polyurethane composite.  POLYMER,  258  (125240). 
15. Qingtao Zeng, Yinan Zhao, Xuejun Lai, Changcheng Jiang, Binglin Wang, Hongqiang Li, Xingrong Zeng, Zhonghua Chen.  (2022)  Skin-inspired multifunctional MXene/cellulose nanocoating for smart and efficient fire protection.  CHEMICAL ENGINEERING JOURNAL,  446  (136899). 
16. Chunjun Zhao, Ruoyu Zhang, Shuai Han, Xiaowen Yan, Keyu Zhao, Xiaoxia Zhu, Lijing Han.  (2022)  Low-temperature activable, carbon dioxide based, highly adhesive and degradable oligo-urethane and its potential application as an auto-detachable dressing.  Materials Chemistry Frontiers,  (12): (1658-1671). 
17. Hao Wu, Jiwen Li, Wanyu Zhang, Tao Chen, Fuchun Liu, En-Hou Han.  (2022)  Supramolecular engineering of nacre-inspired bio-based nanocomposite coatings with exceptional ductility and high-efficient self-repair ability.  CHEMICAL ENGINEERING JOURNAL,  437  (135405). 
18. Zui Liu, Guangqiang Guo, Junqiu Liao, Yongjie Yuan, Hailiang Zhang.  (2022)  Manipulated and Improved Photoinduced Deformation Property of Photoresponsive Liquid Crystal Elastomers by Copolymerization.  MACROMOLECULAR RAPID COMMUNICATIONS,  43  (6): (2100717). 
19. Zhe Wang, Yuetao Liu, Dejin Zhang, Kaiming Zhang, Chuanhui Gao, Yumin Wu.  (2021)  Tough, stretchable and self-healing C-MXenes/PDMS conductive composites as sensitive strain sensors.  COMPOSITES SCIENCE AND TECHNOLOGY,  216  (109042). 
20. Xiaobo Zhu, Wenru Zheng, Haichao Zhao, Liping Wang.  (2021)  Non-covalent assembly of a super-tough, highly stretchable and environmentally adaptable self-healing material inspired by nacre.  Journal of Materials Chemistry A,  (36): (20737-20747). 
21. Huihui Gan, Shaoqiao Li, Yong Zhang, Liping Yu, Jirong Wang, Zhigang Xue.  (2021)  Mechanically Strong and Electrochemically Stable Single-Ion Conducting Polymer Electrolytes Constructed from Hydrogen Bonding.  LANGMUIR,  37  (27): (8270–8280). 
22. Huitao Yu, Yiyu Feng, Long Gao, Can Chen, Zhixing Zhang, Wei Feng.  (2020)  Self-Healing High Strength and Thermal Conductivity of 3D Graphene/PDMS Composites by the Optimization of Multiple Molecular Interactions.  MACROMOLECULES,  53  (16): (7161–7170). 
23. Huimin He, Duo Li, Zifeng Lin, Liuqi Peng, Jirong Yang, Mingming Wu, Delin Cheng, Haobo Pan, Changshun Ruan.  (2020)  Temperature-programmable and enzymatically solidifiable gelatin-based bioinks enable facile extrusion bioprinting.  Biofabrication,  12  (4): (45003). 
24. Yan Yang, Zushan Ye, Xiaoxuan Liu, Jiahui Su.  (2020)  A healable waterborne polyurethane synergistically cross-linked by hydrogen bonds and covalent bonds for composite conductors.  Journal of Materials Chemistry C,  (15): (5280-5292). 
25. Xingyi Dai, Long-Biao Huang, Yuzhang Du, Jiancheng Han, Qiuqun Zheng, Jie Kong, Jianhua Hao.  (2020)  Self-Healing, Flexible, and Tailorable Triboelectric Nanogenerators for Self-Powered Sensors based on Thermal Effect of Infrared Radiation.  ADVANCED FUNCTIONAL MATERIALS,  30  (16): (1910723). 
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33. Qiming Yan, Yang Cao, Qihui Chen, Maochun Hong, Meng Zhou.  (2024)  Inspired by plant body frameworks bionics: Fabrication of self-healing polyvinyl alcohol/cellulose nanocrystals composite hydrogels reinforced by polyurethane sponges for flexible supercapacitors.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  283  (137795). 
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