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2,4,6-Trichlorophenol - analytical standard, high purity , CAS No.88-06-2

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Item Number
T108938
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T108938-250mg
250mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$104.90

Basic Description

Synonyms bmse000678 | Dowicide 2S | NCGC00090873-04 | MHS8C5BAUZ | 2,4,6-Trichlorophenol 10 microg/mL in Methanol | 2,6-Trichlorophenol | BRN 0776729 | Phenachlor | T0390 | 2,4,6,-trichlorophenol | AI3-00142 | AKOS000118986 | 2,4,6-Trichlorophenol 100 microg/mL in
Specifications & Purity analytical standard
Shipped In Normal
Grade analytical standard

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Benzenoids
Class Phenols
Subclass Halophenols
Intermediate Tree Nodes Chlorophenols
Direct Parent P-chlorophenols
Alternative Parents O-chlorophenols  Chlorobenzenes  Aryl chlorides  Organooxygen compounds  Organochlorides  Hydrocarbon derivatives  
Molecular Framework Aromatic homomonocyclic compounds
Substituents 4-chlorophenol - 2-chlorophenol - Halobenzene - Chlorobenzene - Monocyclic benzene moiety - Aryl halide - Aryl chloride - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Organochloride - Organohalogen compound - Aromatic homomonocyclic compound
Description This compound belongs to the class of organic compounds known as p-chlorophenols. These are chlorophenols carrying a iodine at the C4 position of the benzene ring.
External Descriptors trichlorophenol

Associated Targets(Human)

ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CXCL8 Tchem Interleukin-8 (642 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Skin (286 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Cruzipain (33337 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Bacillus subtilis (32866 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

IUPAC Name 2,4,6-trichlorophenol
INCHI InChI=1S/C6H3Cl3O/c7-3-1-4(8)6(10)5(9)2-3/h1-2,10H
InChIKey LINPIYWFGCPVIE-UHFFFAOYSA-N
Smiles C1=C(C=C(C(=C1Cl)O)Cl)Cl
Isomeric SMILES C1=C(C=C(C(=C1Cl)O)Cl)Cl
WGK Germany 3
RTECS SN1575000
UN Number 3077
Packing Group III
Molecular Weight 197.45
Beilstein 776729

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
C2310488 Certificate of Analysis Dec 20, 2024 T108938
A1704064 Certificate of Analysis Jun 21, 2022 T108938

Chemical and Physical Properties

Boil Point(°C) 120°C/39mmHg
Melt Point(°C) 67°C
Molecular Weight 197.400 g/mol
XLogP3 3.700
Hydrogen Bond Donor Count 1
Hydrogen Bond Acceptor Count 1
Rotatable Bond Count 0
Exact Mass 195.925 Da
Monoisotopic Mass 195.925 Da
Topological Polar Surface Area 20.200 Ų
Heavy Atom Count 10
Formal Charge 0
Complexity 108.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

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3. Sainan Wang, Chao Yuan, Wei Chen, Yifan Niu, Yexi Yan, Fan Li, Hongmei Jiang.  (2024)  3D spherical CuO@g-C3N4 composites activating peroxymonosulfate for high efficient degradation of 2,4,6-trichlorophenol: The mechanism of 1O2 generation.  CHEMICAL ENGINEERING JOURNAL,  480  (148050). 
4. Jinxiang Zuo, Donglei Fu, Pengwei Yan, Shuyu Wang, Yabin Li, Linlu Shen, Yizhen Cheng, Jimin Shen, Jing Kang, Zhonglin Chen.  (2024)  Synergistic mechanism of surface oxygen vacancies and metal sites on Al-substituted NiFe2O4 during peroxymonosulfate activation in the solid-water interface for 2,4-D degradation.  CHEMICAL ENGINEERING JOURNAL,  480  (147884). 
5. Shakeel Ahmad, Hyokchol Mun, Mingyi Zhang, Xinzuo Yang, Feilong Gao, Jingchun Tang.  (2024)  Mechanistic details of the removal of 2,4,6-trichlorophenol from aqueous solution by iron and nitrogen co-doped biochar: Characterization, performance, and mechanism studies.  SEPARATION AND PURIFICATION TECHNOLOGY,  332  (125750). 
6. Di Cao, Xueqi Chen, Jun Nan, Aijie Wang, Zhiling Li.  (2023)  Biomolecular insights into the inhibition of heavy metals on reductive dechlorination of 2,4,6-trichlorophenol in Pseudomonas sp. CP-1.  WATER RESEARCH,  247  (120836). 
7. Ping Hu, Shengwen Lei, Weiyan Luo, Xiaoqing Huang, Wei Ruan, Yueyuan Ye, Zhifeng Zheng, Dechao Wang, Duo Wang.  (2023)  Recovery of high-purity-4-chloroguaiacol from bleaching wastewater by a heterogeneous extraction method.  JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY,     
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15. Lu Liu, Jian Wang, Huijuan Yang, Di Gao, Yaya Cui, Hao Chen, Yaxin Qin, Ranfeng Ye, Xing Ding.  (2023)  The critical impacts of pyrochar during 2,4,6-trichlorophenol photochemical remediation process: Cooperation between persistent free radicals and oxygenated functional groups.  ENVIRONMENTAL POLLUTION,  330  (121813). 
16. Ying Wang, Wei Jiang, Yanqiang Tang, Zheming Liu, Qingdong Qin, Yan Xu.  (2023)  Biochar–supported sulfurized nanoscale zero–valent iron facilitates extensive dechlorination and rapid removal of 2,4,6–trichlorophenol in aqueous solution.  CHEMOSPHERE,  332  (138835). 
17. Yangke Long, Shixin Huang, Shiyin Zhao, Guicong Xiao, Jianlin Sun, Dan Peng.  (2023)  Pyrolyzed iron–nitrogen–carbon hybrids for efficient contaminant decomposition via periodate activation: Active site and degradation mechanism.  SEPARATION AND PURIFICATION TECHNOLOGY,  317  (123945). 
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23. Zheng Weiran, Su Ruobing, Lin Xingyu, Liu Jiyang.  (2022)  Nanochannel array modified three-dimensional graphene electrode for sensitive electrochemical detection of 2,4,6-trichlorophenol and prochloraz.  Frontiers in Chemistry,  10   
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27. Yanqiang Tang, Jiafeng Chen, Zhixing Xiao, Zheming Liu, Lei Xu, Qingdong Qin, Yuqiao Wang, Yan Xu.  (2022)  Humin and biochar accelerated microbial reductive dechlorination of 2,4,6-trichlorophenol under weak electrical stimulation.  JOURNAL OF HAZARDOUS MATERIALS,  439  (129671). 
28. Qiang Liu, Yuyu Jiang, Yangyang Liu, Xiaolei Zhang, Yunfeng Xu, Huihui Chen, Weimin Cao.  (2022)  Enhanced 2,4,6-trichlorophenol removal from soil by electrokinetic remediation coupled with biochar in a permeable reactive barrier.  Environmental Technology & Innovation,  28  (102835). 
29. Aimin Li, Xiaolan Huang, Ling Yan, Jing Cheng.  (2022)  Pseudo-template molecularly imprinted polymeric fiber solid-phase microextraction coupled to gas chromatography for ultrasensitive determination of 2,4,6-trihalophenol disinfection by-products.  JOURNAL OF CHROMATOGRAPHY A,  1678  (463322). 
30. Kaiqi Zhang, Hongyan Song, Zhe An, Jian Zhang, Yanru Zhu, Zhigang Chai, Xin Shu, Jing He.  (2022)  Mesoscale Mechanism of P-dopant Defects and Interface Synergy for Phenols Degradation.  Chemistry-An Asian Journal,  17  (16): (e202200476). 
31. Zhong Dan, Feng Weinan, Ma Wencheng, Liu Xinyue, Ma Jun, Zhou Ziyi, Du Xuan, He Fu.  (2022)  Goethite and lepidocrocite catalyzing different double-oxidant systems to degrade chlorophenol.  ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,  29  (48): (72764-72776). 
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34. Lixia Li, Qinkai Guo, Baohe Lv, Minxue Zheng, Wang Zhan, Yanhong Liu, Wanzhen Xu, Ruiwei Wang, Hongbo Zeng, Baodong Mao.  (2022)  Surface modified silver/magnetite nanocomposite activating hydrogen peroxide for efficient degradation of chlorophenols.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  617  (246). 
35. Haotian Zhong, Yuting Xue, Bin Liu, Zhengbo Chen, Kai Li, Xia Zuo.  (2022)  Construction of a colorimetric sensor array based on the coupling reaction to identify phenols.  Analytical Methods,  14  (9): (892-899). 
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37. Tianming Chen, Chao Zou, Fan Chen, Ye Yuan, Jingjing Pan, Qi Zhao, Mansi Wang, Liang Qiao, Haoyi Cheng, Cheng Ding, Aijie Wang.  (2022)  Response of 2,4,6-trichlorophenol-reducing biocathode to burial depth in constructed wetland sediments.  JOURNAL OF HAZARDOUS MATERIALS,  426  (128066). 
38. Zhihui Chen, Jun Yao, Bo Ma, Bang Liu, Jonghyok Kim, Hao Li, Xiaozhe Zhu, Chenchen Zhao, Meseret Amde.  (2022)  A robust biocatalyst based on laccase immobilized superparamagnetic Fe3O4@SiO2–NH2 nanoparticles and its application for degradation of chlorophenols.  CHEMOSPHERE,  291  (132727). 
39. Jingqi Zhang, Hanjun Hu, Jingbo Chao, Yang Tang, Pingyu Wan, Qipeng Yuan, Adrian C. Fisher, Frederic Coulon, Qing Hu, Xiao Jin Yang.  (2022)  Groundwater remediation using Magnesium–Aluminum alloys and in situ layered doubled hydroxides.  ENVIRONMENTAL RESEARCH,  204  (112241). 
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42. Meng Zhang, Yukun Yang, Yuwei Wang, Bo Zhang, Haiyang Wang, Guozhen Fang, Shuo Wang.  (2022)  A molecularly imprinted electrochemical sensor based on cationic intercalated two-dimensional titanium carbide nanosheets for sensitive and selective detection of triclosan in food samples.  FOOD CONTROL,  132  (108532). 
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45. Dong Liu, Chunling Li, Tianjun Ni, Ranpeng Gao, Jiayu Ge, Fengquan Zhang, Weidong Wu, Jinliang Li, Qian Zhao.  (2021)  3D interconnected porous g-C3N4 hybridized with Fe2O3 quantum dots for enhanced photo-Fenton performance.  APPLIED SURFACE SCIENCE,  555  (149677). 
46. Zhenju Bi, Yan Zhao, Jeffrey J. Morrell, Yafang Lei, Li Yan.  (2021)  The antifungal mechanism of konjac flying powder extract and its active compounds against wood decay fungi.  INDUSTRIAL CROPS AND PRODUCTS,  164  (113406). 
47. Yihao Li, Lu Jiang, Rui Wang, Pingxiao Wu, Juan Liu, Shanshan Yang, Jiahao Liang, Guining Lu, Nengwu Zhu.  (2021)  Kinetics and mechanisms of phenolic compounds by Ferrate(VI) assisted with density functional theory.  JOURNAL OF HAZARDOUS MATERIALS,  415  (125563). 
48. Man-Qing Ai, Hao Du, Shuang-Shuang Lv, Xue-Gang Chen, Chu-Qing Zhang, Wei Cai, Wen-Li Qin, Ying Ye, Chun-Hui Tao.  (2021)  Effective removal of 2,4,6-trichlorophenol by FeSx/talc composite under microwave.  Journal of Environmental Chemical Engineering,  (105287). 
49. Juan Zhang, Chen Yu, Zhipeng Chen, Xiaogang Luo, Haiyan Zhao, Fengshou Wu.  (2021)  Zeolitic imidazolate framework-8/ fluorinated graphene coated SiO2 composites for pipette tip solid-phase extraction of chlorophenols in environmental and food samples.  TALANTA,  228  (122229). 
50. Zaiming Chen, Jianfei Wang, Yuefeng Wang, Bing Li, Meizhen Wang.  (2021)  Rapid formation of pyrogenic char (biochar) with high and low sorption capacity towards organic chemicals.  ENVIRONMENTAL POLLUTION,  273  (116472). 
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67. Haifeng Zhuang, Hao Zhu, Jin Zhang, Shengdao Shan, Chengran Fang, Haojie Tang, Qiaona Xie.  (2020)  Enhanced 2,4,6-trichlorophenol anaerobic degradation by Fe3O4 supported on water hyacinth biochar for triggering direct interspecies electron transfer and its use in coal gasification wastewater treatment.  BIORESOURCE TECHNOLOGY,  296  (122306). 
68. Na Tong, Jianqi Yuan, Hao Xu, Shaobin Huang, Congcong Sun, Xiangyu Wen, Yongqing Zhang.  (2019)  Effects of 2,4,6-trichlorophenol on simultaneous nitrification and denitrification: Performance, possible degradation pathway and bacterial community structure.  BIORESOURCE TECHNOLOGY,  290  (121757). 
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92. Jianqing Ma, Qunfeng Yang, Yuezhong Wen, Weiping Liu.  (2017)  Fe-g-C3N4/graphitized mesoporous carbon composite as an effective Fenton-like catalyst in a wide pH range.  APPLIED CATALYSIS B-ENVIRONMENTAL,  201  (232). 
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94. Xiuling Xu, Fan Hu, Saisai Yan, Jianguang Lin, Qing Li, Qi Shuai.  (2016)  Eco-friendly microwave synthesis of Mg(II) phenoxy carboxylic acid coordination compounds with specific motifs driven by multiple hydrogen bonding.  RSC Advances,  (72): (67610-67618). 
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122. Xiaoyan Chen, Jiangdong Cui, Xinyu Yang, Taoyue Yuan, Jiacheng Ge, Mengtao Ma, Shunke Ding, Wenhai Chu.  (2025)  Enhanced removal of phenolic contaminants with permanganate oxidation mediated by SiO2@TEMPO: Performance, transformation pathway, and selectivity.  CHEMICAL ENGINEERING JOURNAL,  503  (158210). 
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124. Liu Jiali, Li Chen, Zhang Shen, Liu Xinni, Wei Xiao, Gao Yue, Wang Fei, Yan Mengwei, Wang Jiaqi, Kamuti Diana.  (2025)  Environment-Friendly Lead-Free Cs3Bi2Br9 Perovskite Quantum Dots as Fluorescent Probes for Rapid Detection of Oxytetracycline Via Inner Filter Effect.  JOURNAL OF CLUSTER SCIENCE,  36  (1): (1-12). 
125. Yu-Jia Nong, Qian-Yuan Wu, Yun-Peng Wu, Ju-Won Lee, Min-Yong Lee, Wen-Long Wang.  (2025)  Far-UVC (UV222) based photolysis, photooxidation, and photoreduction of chlorophenols using a KrCl-excimer lamp: Degradation, dechlorination, and detoxification.  WATER RESEARCH,  268  (122560). 
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127. Yuxin Tu, Heming Li, Yuandi Xue, Wen Xie, Canrong Chen, Yanhui Zhong, Zian Lin, Zongwei Cai.  (2024)  Fluorine-functionalized covalent organic framework coated solid-phase microextraction probe coupled with electrospray ionization mass spectrometry for monitoring triclosan, triclocarban, and chlorophenols in mice.  TALANTA,  278  (126503). 
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135. Jialong Yin, Heng Zhang, Mengfan Luo, Jia Zhao, Bingkun Huang, Pinji Chen, Zhenpeng Cai, Yue Yuan, Yang Liu, Chuanshu He, Bo Lai.  (2024)  Regulating the dominant reactive oxygen species from Fe(IV)-oxo to 1O2 by deprotonation of Fe(IV)-oxo in electro-Fe(II)/periodate system.  CHEMICAL ENGINEERING JOURNAL,  497  (154896). 
136. Shuyun Wang, Siyuan Wang, Rong Tang, Yin Liu, Huan Chen.  (2024)  Removal of mixed pollutants of perfluorooctanoic acid and 2,4,6-trichlorophenol via adsorption-photocatalysis using Ga2O3-Bi4O7 combining with fluorine-doped covalent triazine framework: Role of different active species.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  676  (959). 
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