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2,2′-Bipyridine-5,5′-dicarboxylic acid - 98%, high purity , CAS No.1802-30-8

    Grade & Purity:
  • ≥98%
In stock
Item Number
B123373
Grouped product items
SKU Size
Availability
Price Qty
B123373-250mg
250mg
4
$15.90
B123373-1g
1g
6
$46.90
B123373-5g
5g
1
$141.90
B123373-10g
10g
1
$254.90
B123373-25g
25g
1
$573.90

Basic Description

Synonyms AM20061692 | 5,5'-Dicarboxy-2,2'-bipyridine | 5,5-Dicarboxy-2,2-bipyridine | 6,6'-Dinicotinic acid, United States Pharmacopeia (USP) Reference Standard | STL556639 | Nicotinic Acid Imp. B (EP); 6,6'-Dinicotinic Acid; 2,2'-Bipyridine-5,5'-dicarboxylic Acid
Specifications & Purity ≥98%
Shipped In Normal
Product Description

2,2'-Bipyridine-5,5'-dicarboxylic acid is a nicotinic acid derivative for treatment of hypercholesterolemia and hyperlipidemia and cardiovascular disease.
A nicotinic acid derivative.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organoheterocyclic compounds
Class Pyridines and derivatives
Subclass Bipyridines and oligopyridines
Intermediate Tree Nodes Not available
Direct Parent Bipyridines and oligopyridines
Alternative Parents Pyridinecarboxylic acids  Dicarboxylic acids and derivatives  Heteroaromatic compounds  Carboxylic acids  Azacyclic compounds  Organopnictogen compounds  Organooxygen compounds  Organonitrogen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular Framework Aromatic heteromonocyclic compounds
Substituents Bipyridine - Pyridine carboxylic acid - Pyridine carboxylic acid or derivatives - Dicarboxylic acid or derivatives - Heteroaromatic compound - Azacycle - Carboxylic acid - Carboxylic acid derivative - Hydrocarbon derivative - Organopnictogen compound - Organic oxygen compound - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Organic oxide - Aromatic heteromonocyclic compound
Description This compound belongs to the class of organic compounds known as bipyridines and oligopyridines. These are organic compounds containing two pyridine rings linked to each other.
External Descriptors Not available

Associated Targets(Human)

P4HA1 Tchem Prolyl 4-hydroxylase subunit alpha-1 (2 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
P4HTM Tchem Transmembrane prolyl 4-hydroxylase (2 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
P4HTM Tchem Hypoxia-inducible factor prolyl 4-hydroxylase (111 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
EGLN1 Tclin Egl nine homolog 1 (1702 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
P4HA1 Tchem Prolyl 4-hydroxylase subunit alpha-1 (16 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

rep Replicase polyprotein 1ab (378 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

Pubchem Sid 488188561
Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488188561
IUPAC Name 6-(5-carboxypyridin-2-yl)pyridine-3-carboxylic acid
INCHI InChI=1S/C12H8N2O4/c15-11(16)7-1-3-9(13-5-7)10-4-2-8(6-14-10)12(17)18/h1-6H,(H,15,16)(H,17,18)
InChIKey KVQMUHHSWICEIH-UHFFFAOYSA-N
Smiles C1=CC(=NC=C1C(=O)O)C2=NC=C(C=C2)C(=O)O
Isomeric SMILES C1=CC(=NC=C1C(=O)O)C2=NC=C(C=C2)C(=O)O
WGK Germany 3
Molecular Weight 244.2
Beilstein 214282
Reaxy-Rn 214282
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=214282&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

45 results found

Lot Number Certificate Type Date Item
C2527170 Certificate of Analysis Mar 07, 2025 B123373
C2527180 Certificate of Analysis Mar 07, 2025 B123373
C2527198 Certificate of Analysis Mar 07, 2025 B123373
C2527206 Certificate of Analysis Mar 07, 2025 B123373
B2519098 Certificate of Analysis Dec 17, 2024 B123373
L2423031 Certificate of Analysis Dec 17, 2024 B123373
L2423133 Certificate of Analysis Dec 17, 2024 B123373
L2423134 Certificate of Analysis Dec 17, 2024 B123373
L2423135 Certificate of Analysis Dec 17, 2024 B123373
J2422295 Certificate of Analysis Oct 14, 2024 B123373
G2416153 Certificate of Analysis Jul 10, 2024 B123373
G2416154 Certificate of Analysis Jul 10, 2024 B123373
G2416155 Certificate of Analysis Jul 10, 2024 B123373
G2416156 Certificate of Analysis Jul 10, 2024 B123373
C2429208 Certificate of Analysis Mar 15, 2024 B123373
C2429209 Certificate of Analysis Mar 15, 2024 B123373
C2429210 Certificate of Analysis Mar 15, 2024 B123373
C2429211 Certificate of Analysis Mar 15, 2024 B123373
K2321053 Certificate of Analysis Nov 15, 2023 B123373
K2321054 Certificate of Analysis Nov 15, 2023 B123373
K2321055 Certificate of Analysis Nov 15, 2023 B123373
K2321056 Certificate of Analysis Nov 15, 2023 B123373
K2321057 Certificate of Analysis Nov 15, 2023 B123373
C2411073 Certificate of Analysis Nov 15, 2023 B123373
F2313850 Certificate of Analysis Jun 06, 2023 B123373
F2313843 Certificate of Analysis Jun 06, 2023 B123373
F2313845 Certificate of Analysis Jun 06, 2023 B123373
F2313976 Certificate of Analysis Jun 06, 2023 B123373
D2325940 Certificate of Analysis Apr 18, 2023 B123373
D2325926 Certificate of Analysis Apr 18, 2023 B123373
D2325933 Certificate of Analysis Apr 18, 2023 B123373
D2325928 Certificate of Analysis Apr 18, 2023 B123373
C2314095 Certificate of Analysis Feb 22, 2023 B123373
B2328776 Certificate of Analysis Feb 22, 2023 B123373
B2328778 Certificate of Analysis Feb 22, 2023 B123373
B2328772 Certificate of Analysis Feb 22, 2023 B123373
B2328773 Certificate of Analysis Feb 22, 2023 B123373
B2328774 Certificate of Analysis Feb 22, 2023 B123373
B2328779 Certificate of Analysis Feb 22, 2023 B123373
B2328775 Certificate of Analysis Feb 22, 2023 B123373
C2314096 Certificate of Analysis Feb 22, 2023 B123373
B2328771 Certificate of Analysis Feb 22, 2023 B123373
B2328777 Certificate of Analysis Feb 22, 2023 B123373
B2328784 Certificate of Analysis Feb 22, 2023 B123373
I1812141 Certificate of Analysis Jul 14, 2022 B123373

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Chemical and Physical Properties

Melt Point(°C) 365°C
Molecular Weight 244.200 g/mol
XLogP3 0.500
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 6
Rotatable Bond Count 3
Exact Mass 244.048 Da
Monoisotopic Mass 244.048 Da
Topological Polar Surface Area 100.000 Ų
Heavy Atom Count 18
Formal Charge 0
Complexity 302.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

1. Hao Guo, Likun Luan, Jinde Cai, Xiuling Ji, Haijun Yu, Yuhong Huang.  (2024)  Biomimetic photocatalyst Ce/TCPP-UiO-66-NH2 for NADH regeneration and CO2 activation.  CHEMICAL ENGINEERING JOURNAL,  479  (147720). 
2. Runze Jia, Xianju Zhou, Jian Wu, Li Li, Yongjie Wang, Guotao Xiang, Xiantong Tang, Zhiyu Yang, Huajing Gao.  (2024)  Luminescent properties of multi-stimuli-responsive Ln-BPDC-Phen Lanthanide complexes.  DYES AND PIGMENTS,  222  (111871). 
3. Mengmeng Pan, Ming Wang, Linjiao Yang, Yongli Song, Ming Jiang, Xu Yu, Li Xu.  (2023)  Construction of Metal Organic Framework-Derived Fe-N-C Oxidase Nanozyme for Rapid and Sensitive Detection of Alkaline Phosphatase.  Nanomaterials,  13  (18): (2496). 
4. Yu Wang, Yunlei Shi, Dazhen Xiong, Zhiyong Li, Huiyong Wang, Xiaopeng Xuan, Jianji Wang.  (2023)  Metal chloride functionalized MOF-253(Al) for high-efficiency selective separation of ammonia from H2 and N2.  CHEMICAL ENGINEERING JOURNAL,  474  (145307). 
5. Xiaoyu He, Xutao Gao, Xiao Chen, Shen Hu, Fangchang Tan, Yujie Xiong, Ran Long, Min Liu, Edmund C.M. Tse, Fei Wei, Hong Yang, Jungang Hou, Chunshan Song, Xinwen Guo.  (2023)  Dual-optimization strategy engineered Ti-based metal-organic framework with Fe active sites for highly-selective CO2 photoreduction to formic acid.  APPLIED CATALYSIS B-ENVIRONMENTAL,  327  (122418). 
6. Ying Zhang, Bin Wei, Hao Liang.  (2023)  Rhodium-Based MOF-on-MOF Difunctional Core–Shell Nanoreactor for NAD(P)H Regeneration and Enzyme Directed Immobilization.  ACS Applied Materials & Interfaces,  15  (2): (3442–3454). 
7. Xiu Xing, Yan Liu, Ru-De Lin, Yang Zhang, Zhong-Liu Wu, Xiao-Qi Yu, Kun Li, Na Wang.  (2023)  Development of an Integrated System for Highly Selective Photoenzymatic Synthesis of Formic Acid from CO2.  ChemSusChem,  16  (5): (e202201956). 
8. Yuanyuan Zhang, Jian Liu.  (2022)  Bioinspired Photocatalytic NADH Regeneration by Covalently Metalated Carbon Nitride for Enhanced CO2 Reduction.  CHEMISTRY-A EUROPEAN JOURNAL,  28  (55): (e202201430). 
9. Meng-Meng Pan, Yu Ouyang, Yong-Li Song, Lu-Qin Si, Ming Jiang, Xu Yu, Li Xu, Itamar Willner.  (2022)  Au3+-Functionalized UiO-67 Metal-Organic Framework Nanoparticles: O2•− and •OH Generating Nanozymes and Their Antibacterial Functions.  Small,  18  (23): (2200548). 
10. Minmin Gou, Ruili Guo, Hengheng Cao, Weifang Zhu, Fu Liu, Zhong Wei.  (2022)  An MOF-tailored hierarchical porous microenvironment for CO2 as an efficient filler for mixed matrix membranes.  CHEMICAL ENGINEERING JOURNAL,  438  (135651). 
11. Xiu Xing, Yan Liu, Ming-Liang Shi, Kun Li, Xin-Yue Fan, Zhong-Liu Wu, Na Wang, Xiao-Qi Yu.  (2022)  Preparation of chiral aryl alcohols: a controllable enzymatic strategy via light-driven NAD(P)H regeneration.  NEW JOURNAL OF CHEMISTRY,  46  (13): (6274-6282). 
12. Ting Du, Jing Wang, Liang Zhang, ShaoChi Wang, Chengyuan Yang, Linxuan Xie, Zhaoli Liu, Yongsheng Ni, XiangHong Xie, Jing Sun, Wentao Zhang, Jianlong Wang.  (2022)  Missing-linker engineering of Eu (III)-doped UiO-MOF for enhanced detection of heavy metal ions.  CHEMICAL ENGINEERING JOURNAL,  431  (134050). 
13. Lili Chen, Zihan Cheng, Xinyue Peng, Guoqiao Qiu, Li Wang.  (2021)  Eu-Doped MOF-based high-efficiency fluorescent sensor for detecting 2,4-dinitrophenol and 2,4,6-trinitrophenol simultaneously.  Analytical Methods,  14  (1): (44-51). 
14. Guangyao Zhai, Yuanyuan Liu, Yuyin Mao, Honggang Zhang, Lingtong Lin, Yujie Li, Zeyan Wang, Hefeng Cheng, Peng Wang, Zhaoke Zheng, Ying Dai, Baibiao Huang.  (2022)  Improved photocatalytic CO2 and epoxides cycloaddition via the synergistic effect of Lewis acidity and charge separation over Zn modified UiO-bpydc.  APPLIED CATALYSIS B-ENVIRONMENTAL,  301  (120793). 
15. Hu Cong Yi, Jiang Zhong Wei, Huang Cheng Zhi, Li Yuan Fang.  (2021)  Cu2+-modified MOF as laccase-mimicking material for colorimetric determination and discrimination of phenolic compounds with 4-aminoantipyrine.  MICROCHIMICA ACTA,  188  (8): (1-8). 
16. Xin Zhang, Guoming Xie, Dan Gou, Peng Luo, Yuan Yao, Hui Chen.  (2019)  A novel enzyme-free electrochemical biosensor for rapid detection of Pseudomonas aeruginosa based on high catalytic Cu-ZrMOF and conductive Super P.  BIOSENSORS & BIOELECTRONICS,  142  (111486). 
17. Yimeng Song, Donghui Yang, Shengnan Yu, Xinsheng Teng, Ze Chang, Fusheng Pan, Xianhe Bu, Zhongyi Jiang, Baoyi Wang, Sheng Wang, Xingzhong Cao.  (2019)  Hybrid membranes with Cu(II) loaded metal organic frameworks for enhanced desulfurization performance.  SEPARATION AND PURIFICATION TECHNOLOGY,  210  (258). 
18. Pei Xiu, Bai Jinchuan, Li Yaming, Kong Xiangbo.  (2024)  A Fluorescent Nanoplatform Based on Tb3+@tartric Acid-Functionalized UiO-67-bpy: A New Strategy of Synergistic Sensitization and its Highly Sensitive Performance toward the Detection of Nitenpyram.  Journal of Inorganic and Organometallic Polymers and Materials,    (1-11). 
19. Hao-Cheng Wang, Xiao Liu, Jian-Gong Ma, Peng Cheng.  (2024)  Rapid and high-throughput synthesis of diverse MOFs with centrifuge tube grinding strategy.  GREEN CHEMISTRY,  26  (12): (7312-7319). 
20. Shuai Zhao, Haojia Qin, Jie Huang, Qiang Chen, Shangzhong Jin, Pei Liang.  (2024)  Rapid determination of thiram in lake water using Au/Fe3O4 nanoparticles decorated MOF-867 as efficient surface-enhanced Raman scattering substrate.  Journal of Environmental Chemical Engineering,  12  (112777). 
21. Renquan Guan, Xueying Cheng, Weilong Che, Yunning Chen, Zhengkai Wu, Qingkun Shang.  (2024)  Synergistic Regulation of Hydrophobicity and Carrier Transport Based on Bipyridine Derivatives to Enhance the Photocatalytic Performance of Defective TiO2 for Ammonia Synthesis.  ACS Sustainable Chemistry & Engineering,  12  (11): (4587-4597). 
22. Xiaoqing Li, Gui Wang, Dongyang Zhou, Ziwei Lan, Fengling Jiang, Dickon H. L. Ng, Jia Li.  (2025)  Zirconium Metal–Organic Frameworks as Micromotors with Enzyme-like Activity for Glutathione Detection.  INORGANIC CHEMISTRY,  64  (14): (7096-7109). 

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