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17α-Hydroxypregnenolone - 95%, high purity , CAS No.387-79-1

COA

Grade & Purity:

Moligand™

≥95%

Cas Number: 387-79-1
Molecular Weight: 332.48
EC Number: 206-862-6
PubChem CID: 22796600

In stock

Item Number

H340055

Grouped product items
SKU	Size	Availability	Price
H340055-25mg	25mg	1	$41.90
H340055-100mg	100mg	1	$114.90
H340055-250mg	250mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$258.90

a C21 steroid and prohormone in the formation of DHEA

View related series

Endogenous Metabolite (959) inhibitor (73) Metabolic Enzyme/Protease (4860) Metabolite (5307)

Basic Description

Synonyms	NSC 63853 \| A-Hydroxypregnenolone \| 1-((8R,9S,10R,13S,14S,17R)-3,17-dihydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethanone \| SCHEMBL138937 \| 1-[(3S,8R,9S,10R,13S,17R)-3,17-dihydroxy-10,13-dim
Specifications & Purity	Moligand™, ≥95%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Grade	Moligand™
Product Description	17a-Hydroxypregnenolone is a pregnane steroid. It is a prohormone in the formation of dehydroepiandrosterone (DHEA).

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Lipids and lipid-like molecules
  - Class Steroids and steroid derivatives
    - Subclass Vitamin D and derivatives

Kingdom	Organic compounds
Superclass	Lipids and lipid-like molecules
Class	Steroids and steroid derivatives
Subclass	Vitamin D and derivatives
Intermediate Tree Nodes	Not available
Direct Parent	Vitamin D and derivatives
Alternative Parents	Triterpenoids Gluco/mineralocorticoids, progestogins and derivatives 20-oxosteroids 3-hydroxy delta-5-steroids 17-hydroxysteroids Delta-5-steroids Acyloins Tertiary alcohols Alpha-hydroxy ketones Secondary alcohols Cyclic alcohols and derivatives Organic oxides Hydrocarbon derivatives
Molecular Framework	Aliphatic homopolycyclic compounds
Substituents	Polycyclic triterpenoid - Triterpenoid - Progestogin-skeleton - Pregnane-skeleton - 20-oxosteroid - 17-hydroxysteroid - Oxosteroid - Hydroxysteroid - 3-hydroxysteroid - 3-hydroxy-delta-5-steroid - Delta-5-steroid - Acyloin - Tertiary alcohol - Cyclic alcohol - Alpha-hydroxy ketone - Secondary alcohol - Ketone - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Alcohol - Aliphatic homopolycyclic compound
Description	This compound belongs to the class of organic compounds known as vitamin d and derivatives. These are compounds containing a secosteroid backbone, usually secoergostane or secocholestane.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

SHBG Tchem Sex hormone-binding globulin (0 Activities)

Discover Target: SHBG

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	1-[(8R,9S,10R,13S,14S,17R)-3,17-dihydroxy-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl]ethanone
INCHI	InChI=1S/C21H32O3/c1-13(22)21(24)11-8-18-16-5-4-14-12-15(23)6-9-19(14,2)17(16)7-10-20(18,21)3/h4,15-18,23-24H,5-12H2,1-3H3/t15?,16-,17+,18+,19+,20+,21+/m1/s1
InChIKey	JERGUCIJOXJXHF-QUPIPBJSSA-N
Smiles	CC(=O)C1(CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C)O
Isomeric SMILES	CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CCC(C4)O)C)C)O
WGK Germany	3
RTECS	TU5548000
Molecular Weight	332.48
Reaxy-Rn	3407754
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3407754&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot Number	Certificate Type	Date	Item
G2418621	Certificate of Analysis	Jul 12, 2024	H340055
G2418622	Certificate of Analysis	Jul 12, 2024	H340055
G2418623	Certificate of Analysis	Jul 12, 2024	H340055
A2514181	Certificate of Analysis	Jul 12, 2024	H340055
A2425053	Certificate of Analysis	Jan 13, 2024	H340055
A2425054	Certificate of Analysis	Jan 13, 2024	H340055
A2425055	Certificate of Analysis	Jan 13, 2024	H340055
A2425056	Certificate of Analysis	Jan 13, 2024	H340055
A2425057	Certificate of Analysis	Jan 13, 2024	H340055
E2414157	Certificate of Analysis	Jan 13, 2024	H340055

Chemical and Physical Properties

Solubility	DMF: 0.5mg/mL,DMF:PBS (7.2) (1:1.5): 0.4mg/mL
Molecular Weight	332.500 g/mol
XLogP3	3.100
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	1
Exact Mass	332.235 Da
Monoisotopic Mass	332.235 Da
Topological Polar Surface Area	57.500 Å²
Heavy Atom Count	24
Formal Charge	0
Complexity	596.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	6
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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