VOMITOXIN 15-ACETATE | Deoxynivalenol 15-Acetate | 15-Acetyl-deoxynivalenol 100 microg/mL in Acetonitrile | 15-acetyl-DON | 15-O-Acetyl-4-deoxynivalenol from Fusarium graminearum | 3.ALPHA.,7.ALPHA.)-15-(ACETYLOXY)-12,13-EPOXY-3,7-DIHYDROXYTRICHOTHEC-9-EN
Specifications & Purity
≥98%
Biochemical and Physiological Mechanisms
Type B trichothecene mycotoxin. Deoxynivalenol and 3-Acetyldeoxynivalenol analog. Protein synthesis inhibitor. Binds to rRNA. Induces TNF-α, IL-1β, IL-6, CXCL-2, CCL-2 and CCL-7 mRNA expression. Shows emetic effects in vivo. Oral
Storage Temp
Protected from light,Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description
15-Acetyl-Deoxynivalenol is a a type B trichothecene mycotoxin. A type B trichothecene mycotoxin.
This compound belongs to the class of organic compounds known as trichothecenes. These are sesquiterpene mycotoxins structurally characterized by the presence of an epoxide ring and a benzopyran derivative with a variant number of hydroxyl, acetyl, or other substituents. The most important structural features causing the biological activities of trichothecenes are the 12,13-epoxy ring, the presence of hydroxyl or acetyl groups at appropriate positions on the trichothecene nucleus and the structure and position of the side-chain.
External Descriptors
Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
G2305400