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(12E,20Z,18S)-8-hydroxyvariabilin , CAS No.E607056, Antagonist of glycine receptor α3 subunit

COA

Grade & Purity:

Moligand™

PubChem CID: 54726845

In stock

Item Number

E607056

Grouped product items
SKU	Size	Availability	Price	Qty
E607056-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,400.90
E607056-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

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glycine receptor α3 subunit Antagonist (4)

Basic Description

Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	ANTAGONIST
Mechanism of action	Antagonist of glycine receptor α3 subunit

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Lipids and lipid-like molecules
  - Class Prenol lipids
    - Subclass Terpene lactones

Kingdom	Organic compounds
Superclass	Lipids and lipid-like molecules
Class	Prenol lipids
Subclass	Terpene lactones
Intermediate Tree Nodes	Not available
Direct Parent	Diterpene lactones
Alternative Parents	Diterpenoids Butenolides Vinylogous acids Tertiary alcohols Heteroaromatic compounds Furans Enol esters Enoate esters Lactones Oxacyclic compounds Monocarboxylic acids and derivatives Enols Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	Diterpene lactone - Diterpenoid - 2-furanone - Dihydrofuran - Enol ester - Furan - Tertiary alcohol - Enoate ester - Alpha,beta-unsaturated carboxylic ester - Vinylogous acid - Heteroaromatic compound - Lactone - Carboxylic acid ester - Monocarboxylic acid or derivatives - Enol - Carboxylic acid derivative - Organoheterocyclic compound - Oxacycle - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Alcohol - Organic oxide - Aromatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as diterpene lactones. These are diterpenoids containing a lactone moiety.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

GLRA1 Tclin Glycine receptor subunit alpha-1 (1 Activities)

Discover Target: GLRA1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GLRA3 Tchem Glycine receptor subunit alpha-3 (2 Activities)

Discover Target: GLRA3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(5Z)-5-[(2S,6E)-13-(furan-3-yl)-10-hydroxy-2,6,10-trimethyltridec-6-en-1-ylidene]-4-hydroxy-3-methyl-2,5-dihydrofuran-2-one
INCHI	InChI=1S/C25H36O5/c1-18(8-5-9-19(2)16-22-23(26)20(3)24(27)30-22)10-6-13-25(4,28)14-7-11-21-12-15-29-17-21/h10,12,15-17,19,26,28H,5-9,11,13-14H2,1-4H3/b18-10+,22-16-/t19-,25?/m0/s1
InChIKey	QFBUNOKEKXMSCV-UYYPKTQPSA-N
Smiles	C/C(=C\CCC(CCCc1cocc1)(O)C)/CCC[C@@H](/C=C/1\OC(=O)C(=C1O)C)C
Isomeric SMILES	CC1=C(/C(=C/[C@@H](C)CCC/C(=C/CCC(C)(CCCC2=COC=C2)O)/C)/OC1=O)O
PubChem CID	54726845

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