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1-Methyladenosine - ≥98%, high purity , CAS No.15763-06-1

2 Citations

COA

Grade & Purity:

≥98%

Cas Number: 15763-06-1
Molecular Weight: 281.27
PubChem CID: 27476

In stock

Item Number

M303015

Grouped product items
SKU	Size	Availability	Price
M303015-10mg	10mg	2	$23.90
M303015-25mg	25mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$49.90
M303015-50mg	50mg	2	$85.90
M303015-100mg	100mg	2	$139.90
M303015-250mg	250mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$299.90
M303015-1g	1g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$899.90

View related series

Cell Cycle (2830) Endogenous Metabolite (959) Hedgehog (25) Lipid metabolism (1912) Metabolite (5307) PPAR (155)

Basic Description

Synonyms	H10051 \| AC-32347 \| Adenosine, N,6-didehydro-1,9-dihydro-1-methyl- \| HY-113081 \| (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-imino-1-methyl-1H-purin-9(6H)-yl)tetrahydrofuran-3,4-diol \| NCGC00163305-01 \| Adenosine, 1-methyl- \| AKOS030241121 \| PD018070 \| Q161643 \|
Specifications & Purity	≥98%
Storage Temp	Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	1-Methyladenosine is an RNA modification that can serve as a tumor marker, with elevated levels in the body associated with cancer development. Following 1-methyladenosine methylation, upregulation of PPARδ expression regulates cholesterol metabolism and activates Hedgehog signaling pathway, driving liver tumorigenesis.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Nucleosides, nucleotides, and analogues
  - Class Purine nucleosides

Kingdom	Organic compounds
Superclass	Nucleosides, nucleotides, and analogues
Class	Purine nucleosides
Subclass	Not available
Intermediate Tree Nodes	Not available
Direct Parent	Purine nucleosides
Alternative Parents	Glycosylamines Pentoses Purines and purine derivatives Pyrimidines and pyrimidine derivatives N-substituted imidazoles Imidolactams Tetrahydrofurans Heteroaromatic compounds Secondary alcohols Oxacyclic compounds Azacyclic compounds Primary alcohols Organopnictogen compounds Organonitrogen compounds Hydrocarbon derivatives
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Purine nucleoside - Glycosyl compound - N-glycosyl compound - Pentose monosaccharide - Imidazopyrimidine - Purine - Monosaccharide - N-substituted imidazole - Imidolactam - Pyrimidine - Heteroaromatic compound - Azole - Imidazole - Tetrahydrofuran - Secondary alcohol - Organoheterocyclic compound - Azacycle - Oxacycle - Primary alcohol - Organopnictogen compound - Organooxygen compound - Organonitrogen compound - Alcohol - Organic oxygen compound - Hydrocarbon derivative - Organic nitrogen compound - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as purine nucleosides. These are compounds comprising a purine base attached to a ribosyl or deoxyribosyl moiety.
External Descriptors	methyladenosine
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

RGS4 Tchem Regulator of G-protein signaling 4 (13867 Activities)

Discover Target: RGS4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	(2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-imino-1-methylpurin-9-yl)oxolane-3,4-diol
INCHI	InChI=1S/C11H15N5O4/c1-15-3-14-10-6(9(15)12)13-4-16(10)11-8(19)7(18)5(2-17)20-11/h3-5,7-8,11-12,17-19H,2H2,1H3/t5-,7-,8-,11-/m1/s1
InChIKey	GFYLSDSUCHVORB-IOSLPCCCSA-N
Smiles	CN1C=NC2=C(C1=N)N=CN2C3C(C(C(O3)CO)O)O
Isomeric SMILES	CN1C=NC2=C(C1=N)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O
Molecular Weight	281.27
Reaxy-Rn	1225433
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1225433&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

22 results found

Lot Number	Certificate Type	Date	Item
H2231739	Certificate of Analysis	Jun 09, 2025	M303015
H2231507	Certificate of Analysis	Jun 09, 2025	M303015
H2231506	Certificate of Analysis	Jun 09, 2025	M303015
E2516669	Certificate of Analysis	May 06, 2025	M303015
E2516670	Certificate of Analysis	May 06, 2025	M303015
E2516689	Certificate of Analysis	May 06, 2025	M303015
E2516690	Certificate of Analysis	May 06, 2025	M303015
E2516691	Certificate of Analysis	May 06, 2025	M303015
E2516722	Certificate of Analysis	May 06, 2025	M303015
J2424718	Certificate of Analysis	Oct 12, 2024	M303015
J2424719	Certificate of Analysis	Oct 12, 2024	M303015
J2424720	Certificate of Analysis	Oct 12, 2024	M303015
J2424715	Certificate of Analysis	Oct 12, 2024	M303015
J2424713	Certificate of Analysis	Oct 12, 2024	M303015
J2424714	Certificate of Analysis	Oct 12, 2024	M303015
J2424727	Certificate of Analysis	Oct 12, 2024	M303015
J2424716	Certificate of Analysis	Oct 12, 2024	M303015
J2424717	Certificate of Analysis	Oct 12, 2024	M303015
C2303184	Certificate of Analysis	Jun 08, 2022	M303015
H2231508	Certificate of Analysis	Jun 08, 2022	M303015
H2231503	Certificate of Analysis	Jun 08, 2022	M303015
H2231504	Certificate of Analysis	Jun 08, 2022	M303015

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Chemical and Physical Properties

Solubility	DMSO (Slightly), Water (Slightly, Sonicated)
Sensitivity	light & Moisture sensitive
Molecular Weight	281.270 g/mol
XLogP3	-1.000
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	2
Exact Mass	281.112 Da
Monoisotopic Mass	281.112 Da
Topological Polar Surface Area	127.000 Å²
Heavy Atom Count	20
Formal Charge	0
Complexity	433.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	4
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Mengzhe Guo, Liyan Zhang, Yan Du, Wencheng Du, Dantong Liu, Cheng Guo, Yuanjiang Pan, Daoquan Tang. (2018) Enrichment and Quantitative Determination of 5-(Hydroxymethyl)-2′-deoxycytidine, 5-(Formyl)-2′-deoxycytidine, and 5-(Carboxyl)-2′-deoxycytidine in Human Urine of Breast Cancer Patients by Magnetic Hyper-Cross-Linked Microporous Polymers Based on Polyionic Liquid. ANALYTICAL CHEMISTRY, 90 (6): (3906–3913).
2. Dan-Qian Chen,Gang Cao,Hua Chen,Dan Liu,Wei Su,Xiao-Yong Yu,Nosratola D Vaziri,Xiu-Hua Liu,Xu Bai,Li Zhang,Ying-Yong Zhao. (2017-03-28) Gene and protein expressions and metabolomics exhibit activated redox signaling and wnt/β-catenin pathway are associated with metabolite dysfunction in patients with chronic kidney disease.. Redox biology, 12 (505-521).

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