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1,4-Dithioerythritol - for molecular biology,≥99%, high purity , CAS No.6892-68-8

5 Citations

COA

Grade & Purity:

for molecular biology

≥99%

Cas Number: 6892-68-8
Molecular Weight: 154.25
Beilstein Registry Number: 1719756
EC Number: 229-998-8
MDL number: MFCD00063750
PubChem CID: 439352

In stock

Item Number

D105711

Grouped product items
SKU	Size	Availability	Price
D105711-1g	1g	2	$20.90
D105711-5g	5g	3	$80.90
D105711-25g	25g	3	$363.90
D105711-100g	100g	2	$1,308.90

Reducing agent for maintaining sulfhydryl groups in the reduced state.

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Biochemical Assay Reagents (928)

Basic Description

Synonyms	ERYTHRO-1,4,-DIMERCAPTO-2,3-BUTANEDIOL \| R4SVL81GQI \| D1320 \| HY-15916 \| (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL \| D89833 \| 1,4-Dithioerythritol \| EINECS 229-998-8 \| VHJLVAABSRFDPM-ZXZARUISSA-N \| (2R,3S)-1,4-dimercaptobutane-2,3-diol \| DTU \| 3-01-00-02359
Specifications & Purity	for molecular biology, ≥99%
Biochemical and Physiological Mechanisms	Reducing agent for maintaining sulfhydryl groups in the reduced state. Protective agent for thiol groups and strong reducing agent that is capable of reducing disulfide bonds.
Storage Temp	Store at 2-8°C,Argon charged
Shipped In	Wet ice This product requires cold chain shipping. Ground and other economy services are not available.
Grade	for molecular biology
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Dithioerythritol is an epimer of dithiothreitol and an erythro isomer of 2,3-dihydroxy-1,4- dithiolbutane. The compound is a protective agent for thiol groups and strong reducing agent that is capable of reducing disulfide bonds. A useful reagent for maintaining sulfhydryl groups in the reduced state

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic oxygen compounds
  - Class Organooxygen compounds
    - Subclass Alcohols and polyols
      - Level5 Polyols
        Level6 1,2-diols

Kingdom	Organic compounds
Superclass	Organic oxygen compounds
Class	Organooxygen compounds
Subclass	Alcohols and polyols
Intermediate Tree Nodes	Polyols
Direct Parent	1,2-diols
Alternative Parents	Secondary alcohols Alkylthiols Hydrocarbon derivatives
Molecular Framework	Aliphatic acyclic compounds
Substituents	Secondary alcohol - 1,2-diol - Alkylthiol - Hydrocarbon derivative - Organosulfur compound - Aliphatic acyclic compound
Description	This compound belongs to the class of organic compounds known as 1,2-diols. These are polyols containing an alcohol group at two adjacent positions.
External Descriptors	1,4-dimercaptobutane-2,3-diol
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	(2R,3S)-1,4-bis(sulfanyl)butane-2,3-diol
INCHI	InChI=1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4+
InChIKey	VHJLVAABSRFDPM-ZXZARUISSA-N
Smiles	C(C(C(CS)O)O)S
Isomeric SMILES	C([C@H]([C@H](CS)O)O)S
WGK Germany	3
RTECS	KF2410000
Molecular Weight	154.25
Beilstein	1719756
Reaxy-Rn	9483598
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=9483598&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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7 results found

Lot Number	Certificate Type	Date	Item
C2507047	Certificate of Analysis	Mar 19, 2025	D105711
L2215068	Certificate of Analysis	Sep 11, 2024	D105711
L2215114	Certificate of Analysis	Sep 11, 2024	D105711
L2215052	Certificate of Analysis	Sep 11, 2024	D105711
L2215081	Certificate of Analysis	Sep 11, 2024	D105711
E2118058	Certificate of Analysis	Feb 13, 2023	D105711
H1822073	Certificate of Analysis	Apr 26, 2022	D105711

Chemical and Physical Properties

Solubility	Soluble in water (50 mg/ml), and methanol.
Sensitivity	Moisture sensitive;Heat sensitive;Air sensitive
Melt Point(°C)	82-86°C
Molecular Weight	154.300 g/mol
XLogP3	-0.400
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Exact Mass	154.012 Da
Monoisotopic Mass	154.012 Da
Topological Polar Surface Area	42.500 Å²
Heavy Atom Count	8
Formal Charge	0
Complexity	52.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Alternative Products

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Jie Wang, Shanshan Huang, Kangle Yan, Jihua Shi, Shuo Shi, Yu Jin, Liang Yuan. (2023) Sustainable macromolecular antioxidants from eugenol with synergistically enhanced storage stability for active PVA packaging. REACTIVE & FUNCTIONAL POLYMERS, 191 (105671).
2. Hongzhi Yang, Fengqin Yin, Yeling Mo, Kaixuan Huo, Kun Zhang, Hui Cao, Min Yuan, Tai Ye, Chunyan Luo, Fei Xu. (2023) An ion imprinted electrochemical sensor based on flower-like gold nanoparticles for the detection of trace arsenic(III) ions in water and food samples. ELECTROANALYSIS, 35 (8): (e202200513).
3. Rui Zhao, Xiufeng Cao, Xinxin Li, Tao Li, Hong Zhang, Xiaowei Cui, Zhaojie Cui. (2023) Ecological toxicity of Cd, Pb, Zn, Hg and regulation mechanism in Solanum nigrum L.. CHEMOSPHERE, 313 (137447).
4. Zhihong Yin, Shuangxi Li, Dan Hu, Zhuo Li, Ruoyu Chu, Chenchen Liu, Xinzhu Li, Jiangjun Hu, Liandong Zhu. (2022) Performance evaluation of different chitosan-clay composite materials for efficient harvesting of Chlorella vulgaris and impacts on downstream bioproduct processing and water reusability. CHEMICAL ENGINEERING JOURNAL, 430 (132892).
5. Pengchong Wang, Yan Yan, Ying Sun, Rui Zhang, Chuanchuan Huo, Lu Li, Ke Wang, Yalin Dong, Jianfeng Xing. (2019) Bioreducible and acid-labile polydiethylenetriamines with sequential degradability for efficient transgelin-2 siRNA delivery. Journal of Materials Chemistry B, 7 (44): (6994-7005).

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