Selective focal adhesion kinase (FAK) autophosphorylation inhibitor (IC 50 = 1 μM). No significant activity at other kinases including EGFR, PDGFR and IGF-RI. Increases cell detachment and inhibits cell adhesion in cancer cells. Anticancer agent.
Température de stockage
Room temperature
Expédié en
Normal
Grade
Moligand™
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description
1,2,4,5-Benzenetetraminetetrahydrochloride is widely used as a novel source of carbon and nitrogen insynthesizing benzimidazole-linked polymers and carbon dot nanomaterials.
Application：
1,2,4,5-Benzenetetramine tetrahydrochloride can be used as a precursor in the synthesis of: A pyrene-based benzimidazole-linked polymer by the co-condensation with 1,3,6,8-tetrakis(4-formylphenyl)pyrene in dimethylformamide. Triazine-based benzimidazole-linked polymers for highly selective CO2 capture. Nitrogen-doped carbon dots (NCDs) by simple hydrothermal method, applicable as a highly selective fluorescent probe for sensing Mg2+ ions in an aqueous solution. Red-emitting carbon dots via the solvothermal method.
This compound belongs to the class of organic compounds known as aniline and substituted anilines. These are organic compounds containing an aminobenzene moiety.
External Descriptors
Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
5 Citations
A2514532
